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Recent deep learning methods for fMRI-based diagnosis have achieved promising accuracy by modeling functional connectivity networks. However, standard approaches often struggle with noisy interactions, and conventional post-hoc attribution…

Machine Learning · Computer Science 2026-02-25 Kunyu Zhang , Yanwu Yang , Jing Zhang , Xiangjie Shi , Shujian Yu

Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Ayushi Raj Bhatt , Rajkumar Vaghashiya , Meghna Kulkarni , Dr Prakash Kamaraj

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

Medical image analysis is a vibrant research area that offers doctors and medical practitioners invaluable insight and the ability to accurately diagnose and monitor disease. Machine learning provides an additional boost for this area.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Athanasios Vlontzos , Daniel Rueckert , Bernhard Kainz

End-to-end deep learning models fed with multi-band galaxy images are powerful data-driven tools used to estimate galaxy physical properties in the absence of spectroscopy. However, due to a lack of interpretability and the associational…

Instrumentation and Methods for Astrophysics · Physics 2025-11-26 Wei Zhang , Qiufan Lin , Yuan-Sen Ting , Shupei Chen , Hengxin Ruan , Song Li , Yifan Wang

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

The development of computational pathology lies in the consensus that pathological characteristics of tumors are significant guidance for cancer diagnostics. Most existing research focuses on the inner-contextual information within each WSI…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Jun Shi , Tong Shu , Zhiguo Jiang , Wei Wang , Haibo Wu , Yushan Zheng

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yiran Song , Yikai Zhang , Shuang Zhou , Guojun Xiong , Xiaofeng Yang , Nian Wang , Fenglong Ma , Rui Zhang , Mingquan Lin

Although image restoration has advanced significantly, most existing methods target only a single type of degradation. In real-world scenarios, images often contain multiple degradations simultaneously, such as rain, noise, and haze,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Hu Gao , Xiaoning Lei , Xichen Xu , Depeng Dang , Lizhuang Ma

In this paper, an innovative microwave imaging (MI) approach for breast tumor diagnosis is proposed that employs a differential formulation of the inverse scattering problem (ISP) at hand to exploit arbitrary-fidelity priors on the…

Signal Processing · Electrical Eng. & Systems 2024-01-08 Francesco Zardi , Luca Tosi , Marco Salucci , Andrea Massa

Current multimodal fusion approaches in computational oncology primarily focus on integrating multi-gigapixel histology whole slide images (WSIs) with genomic or transcriptomic data, demonstrating improved survival prediction. We…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Manahil Raza , Ayesha Azam , Talha Qaiser , Nasir Rajpoot

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Imaging mass spectrometry (IMS) has transformed proteomics by providing an avenue for collecting spatially distributed molecular data. Mass spectrometry data acquired with matrix assisted laser desorption ionization (MALDI) IMS consist of…

Applications · Statistics 2016-02-05 Lyron J. Winderbaum , Inge Koch , Ove J. R. Gustafsson , Stephan Meding , Peter Hoffmann

Predicting traits from images lacking visual cues is challenging, as algorithms are designed to capture visually correlated ground truth. This problem is critical in biomedical sciences, and their solution can improve the efficacy of…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Shivam Kumar , Samrat Chatterjee

Artificial intelligence holds great promise in medical imaging, especially histopathological imaging. However, artificial intelligence algorithms cannot fully explain the thought processes during decision-making. This situation has brought…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Tuncay Yiğit , Nilgün Şengöz , Özlem Özmen , Jude Hemanth , Ali Hakan Işık

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

Glioblastoma, IDH-wildtype (GBM-IDHwt) is the most common malignant brain tumor. While histomorphology is a crucial component of GBM-IDHwt diagnosis, it is not further considered for prognosis. Here, we present an explainable artificial…

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah

Susceptibility tensor imaging (STI) is an emerging magnetic resonance imaging technique that characterizes the anisotropic tissue magnetic susceptibility with a second-order tensor model. STI has the potential to provide information for…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Zhenghan Fang , Kuo-Wei Lai , Peter van Zijl , Xu Li , Jeremias Sulam
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