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This paper presents the results of an experimental study of graph partitioning. We describe a new heuristic technique, path optimization, and its application to two variations of graph partitioning: the max_cut problem and the…

Combinatorics · Mathematics 2016-09-06 Jonathan Berry , Mark Goldberg

In this paper, we explore the graph partitioning problem, a pivotal combina-torial optimization challenge with extensive applications in various fields such as science, technology, and business. Recognized as an NP-hard prob-lem, graph…

Machine Learning · Computer Science 2023-12-13 Vivek Chaudhary

Many standard structural quantities, such as order parameters and correlation functions, exist for common condensed matter systems, such as spherical and rod-like particles. However, these structural quantities are often insufficient for…

Soft Condensed Matter · Physics 2012-01-18 Aaron S. Keys , Christopher R. Iacovella , Sharon C. Glotzer

The classical image segmentation algorithm based on local adaptive threshold can effectively segment images with uneven illumination, but with the increase of the image data, the real-time problem gradually emerges. In this paper, a quantum…

Quantum Physics · Physics 2024-05-14 Lu Wang , Wenjie Liu

Graphical models are ubiquitous tools to describe the interdependence between variables measured simultaneously such as large-scale gene or protein expression data. Gaussian graphical models (GGMs) are well-established tools for…

Methodology · Statistics 2020-01-09 Nilabja Guha , Veera Baladandayuthapani , Bani K. Mallick

Accurate prediction of protein active-site structures remains a central challenge in structural biology, particularly for short and flexible peptide fragments where conventional and simulation-based methods often fail. Here, we present a…

Efficient sampling from a classical Gibbs distribution is an important computational problem with applications ranging from statistical physics over Monte Carlo and optimization algorithms to machine learning. We introduce a family of…

Quantum Physics · Physics 2021-09-08 Dominik S. Wild , Dries Sels , Hannes Pichler , Cristian Zanoci , Mikhail D. Lukin

Partitioning a graph into blocks of roughly equal weight while cutting only few edges is a fundamental problem in computer science with numerous practical applications. While shared-memory parallel partitioners have recently matured to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-06 Peter Sanders , Daniel Seemaier

Graphical models are useful tools for describing structured high-dimensional probability distributions. Development of efficient algorithms for generating unbiased and independent samples from graphical models remains an active research…

Quantum Physics · Physics 2026-04-02 Nico Piatkowski , Christa Zoufal

In this work, we present the first implementation of the face-centered cubic (FCC) lattice model for protein structure prediction with a quantum algorithm. Our motivation to encode the FCC lattice stems from our observation that the FCC…

We develop a theory of aggregation using statistical mechanical methods. An example of a complicated aggregation system with several levels of structures is peptide/protein self-assembly. The problem of protein aggregation is important for…

Biomolecules · Quantitative Biology 2023-07-19 John S. Schreck , Jian-Min Yuan

A comparative classification scheme provides a good basis for several approaches to understand proteins, including prediction of relations between their structure and biological function. But it remains a challenge to combine a…

Biomolecules · Quantitative Biology 2015-05-20 Shuangwei Hu , Andrei Krokhotin , Antti J. Niemi , Xubiao Peng

Large scale numerical experiments are commonplace today in theoretical physics. The high performance algorithms described herein are the most compact, efficient methods known for representing and analyzing systems modeled well by sets or…

General Relativity and Quantum Cosmology · Physics 2018-05-14 William J. Cunningham

Sampling technique has become one of the recent research focuses in the graph-related fields. Most of the existing graph sampling algorithms tend to sample the high degree or low degree nodes in the complex networks because of the…

Social and Information Networks · Computer Science 2018-02-02 Junpeng Zhu , Hui Li , Mei Chen , Zhenyu Dai , Ming Zhu

Quantum neural networks are expected to be a promising application in near-term quantum computing, but face challenges such as vanishing gradients during optimization and limited expressibility by a limited number of qubits and shallow…

Quantum Physics · Physics 2026-04-06 Yoshiaki Kawase

Quantum annealers offer an efficient way to compute high quality solutions of NP-hard problems when expressed in a QUBO (quadratic unconstrained binary optimization) or an Ising form. This is done by mapping a problem onto the physical…

Quantum Physics · Physics 2022-04-26 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

An important objective for analyzing real-world graphs is to achieve scalable performance on large, streaming graphs. A challenging and relevant example is the graph partition problem. As a combinatorial problem, graph partition is NP-hard,…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-11-10 Edward Kao , Vijay Gadepally , Michael Hurley , Michael Jones , Jeremy Kepner , Sanjeev Mohindra , Paul Monticciolo , Albert Reuther , Siddharth Samsi , William Song , Diane Staheli , Steven Smith

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

We compare different analytical and numerical methods for studying the partitions of a finite system into fragments. We propose a new numerical method of exploring the partition space by generating the Markov chains of partitions based on…

Mathematical Physics · Physics 2009-10-31 A. S. Botvina , A. D. Jackson , I. N. Mishustin

Hypergraph partitioning is a fundamental optimization problem with applications in data management and other domains involving higher-order relations. In this paper, we study balanced hypergraph partitioning from the perspective of quantum…

Social and Information Networks · Computer Science 2026-05-05 Yiran Li , Y. Batuhan Yilmaz , Michael Silver , Zachary Vernec , Hans-Arno Jacobsen