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The advent of high-throughput sequencing technologies has made data from DNA material readily available, leading to a surge of microbiome-related research establishing links between markers of microbiome health and specific outcomes.…

Methodology · Statistics 2018-06-19 Susheela P. Singh , Ana-Maria Staicu , Robert R. Dunn , Noah Fierer , Brian J. Reich

Many studies have been performed to characterize the dynamics and stability of the microbiome across a range of environmental contexts [Costello et al., 2012, Faust et al., 2015]. For example, it is often of interest to identify time…

Applications · Statistics 2017-12-04 Kris Sankaran , Susan P. Holmes

Despite major environmental and genetic differences, microbial metabolic networks are known to generate consistent physiological outcomes across vastly different organisms. This remarkable robustness suggests that, at least in bacteria,…

Molecular Networks · Quantitative Biology 2022-05-24 Anna Paola Muntoni , Alfredo Braunstein , Andrea Pagnani , Daniele De Martino , Andrea De Martino

A simulation approach to the stochastic growth of bacterial towers is presented, in which a non-uniform and finite nutrient supply essentially determines the emerging structure through elementary chemotaxis. The method is based on cellular…

Populations and Evolution · Quantitative Biology 2009-11-10 J. O. Indekeu , C. V. Giuraniuc

The prediction of crop yields internationally is a crucial objective in agricultural research. Thus, this study implements 6 regression models (Linear, Tree, Gradient Descent, Gradient Boosting, K Nearest Neighbors, and Random Forest) to…

Biochars are an exciting class of environmental materials with a wide range of applications, including carbon storage and sequestration, soil enhancement, and pollution remediation. However, the limited knowledge of their molecular…

Materials Science · Physics 2024-04-09 Audrey Ngambia , Ondřej Mašek , Valentina Erastova

The influence of the microstructure of a polycrystalline material on its macroscopic deformation response is still one of the major problems in materials engineering. For materials characterized by elastic-plastic deformation responses,…

Materials Science · Physics 2022-02-07 Jan N. Fuhg , Lloyd van Wees , Mark Obstalecki , Paul Shade , Nikolaos Bouklas , Matthew Kasemer

Marine microorganisms often reach high swimming speeds, either to take advantage of evanescent nutrient patches or to beat Brownian forces. Since this implies that a sizable part of their energetic budget must be allocated to motion, it is…

Biological Physics · Physics 2015-06-16 Mario E. Di Salvo , C. A. Condat

Fluorescent and luminescent gene reporters allow us to dynamically quantify changes in molecular species concentration over time on the single cell level. The mathematical modeling of their interaction through multivariate dynamical models…

Quantitative Methods · Quantitative Biology 2009-07-07 Michal Komorowski , Barbel Finkenstadt , Claire V. Harper , David A. Rand

As the impending consequences of climate change loom over the Earth, it has become vital for researchers to understand the role microorganisms play in this process. In this paper, we examine how environmental factors, including moisture…

Populations and Evolution · Quantitative Biology 2023-11-30 John Blackwelder , Steven DiSilvio , Anthony Ozerov

This is the second paper of a series which aims at quantifying the uncertainties in chemical evolution model predictions related to the underlying model assumptions. Specifically, it deals with the uncertainties due to the choice of the…

Astrophysics of Galaxies · Physics 2015-05-19 D. Romano , A. I. Karakas , M. Tosi , F. Matteucci

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

Mechanical stresses stemming from environmental factors are a key determinant of cellular behavior and physiology. Yet, the role of self-induced biomechanical stresses in growing bacterial colonies has remained largely unexplored. Here, we…

Soft Condensed Matter · Physics 2023-11-27 René Wittmann , G. H. Philipp Nguyen , Hartmut Löwen , Fabian J. Schwarzendahl , Anupam Sengupta

Correlations between planetary and stellar properties, particularly age, can provide insight on planetary formation and evolution processes. However, the underlying source of such trends can be unclear, and measurement uncertainties and…

Earth and Planetary Astrophysics · Physics 2022-03-30 Emily D. Safsten , Rebekah I. Dawson

Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have…

Computation · Statistics 2018-03-13 Richard J. Boys , Holly F. Ainsworth , Colin S. Gillespie

A macroscopic theory for describing cellular states during steady-growth is presented, which is based on the consistency between cellular growth and molecular replication, as well as the robustness of phenotypes against perturbations.…

Populations and Evolution · Quantitative Biology 2021-02-08 Kunihiko Kaneko , Chikara Furusawa

One of the major characteristics of living organisms is metabolic rate, which is the amount of energy produced per unit of time. When the mass of organisms increases, the metabolic rate also increases (usually as a power function of mass),…

Other Quantitative Biology · Quantitative Biology 2024-12-02 Yuri K. Shestopaloff

We present a framework for the computation of effective stellar yields that accounts for a mixed population of binary and single stars under an adjustable mix of binary evolution settings: the binary fraction, the accretion efficiencies of…

Solar and Stellar Astrophysics · Physics 2025-09-17 Alex Kemp , Tejpreet Kaur

Effective plant growth and yield prediction is an essential task for greenhouse growers and for agriculture in general. Developing models which can effectively model growth and yield can help growers improve the environmental control for…

Machine Learning · Computer Science 2019-07-03 Bashar Alhnaity , Simon Pearson , Georgios Leontidis , Stefanos Kollias

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates