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Recent advances in agentic AI have enabled increasingly autonomous workflows, but existing systems still face substantial challenges in achieving reliable deployment in real-world scientific research. In this work, we present a safe,…

Artificial Intelligence · Computer Science 2026-04-16 Qibin Liu , Julia Gonski

Modern large-scale scientific discovery requires multidisciplinary collaboration across diverse computing facilities, including High Performance Computing (HPC) machines and the Edge-to-Cloud continuum. Integrated data analysis plays a…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-21 Renan Souza , Tyler J. Skluzacek , Sean R. Wilkinson , Maxim Ziatdinov , Rafael Ferreira da Silva

Most education and workplace learning takes place in classroom contexts far removed from laboratories or field sites with special arrangements for scientific research. But digital online resources provide a novel opportunity for large scale…

Computers and Society · Computer Science 2015-02-17 Joseph Jay Williams , Juho Kim , Brian C. Keegan

The connect-fill-run workflow paradigm, widely adopted in mature software engineering, accelerates collaborative development. However, computational chemistry, computational materials science, and computational biology face persistent…

Chemical Physics · Physics 2025-08-12 Jianan Wang , Wenbo Guo , Xin Yue , Minjie Xu , Yueqiang Zheng , Jingxiang Dong , Jiarui Hu , Jian Xia , Chuixiong Wu

The intelligent Distributed Dispatch and Scheduling (iDDS) service is a versatile workflow orchestration system designed for large-scale, distributed scientific computing. iDDS extends traditional workload and data management by integrating…

The last five years have seen the rapid rise in popularity of what we term internet distributed applications (IDAs). These are internet applications with which many users interact simultaneously. IDAs range from P2P file-sharing…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-06-15 Mark Anthony McLaughlin

Rosetta is a science platform for resource-intensive, interactive data analysis which runs user tasks as software containers. It is built on top of a novel architecture based on framing user tasks as microservices - independent and…

Instrumentation and Methods for Astrophysics · Physics 2022-09-07 Stefano Alberto Russo , Sara Bertocco , Claudio Gheller , Giuliano Taffoni

Aneka is a platform for deploying Clouds developing applications on top of it. It provides a runtime environment and a set of APIs that allow developers to build .NET applications that leverage their computation on either public or private…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-07-28 Christian Vecchiola , Xingchen Chu , Rajkumar Buyya

Keeping track of scientific challenges, advances and emerging directions is a fundamental part of research. However, researchers face a flood of papers that hinders discovery of important knowledge. In biomedicine, this directly impacts…

Many existing scientific workflows require High Performance Computing environments to produce results in a timely manner. These workflows have several software library components and use different environments, making the deployment and…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-26 Liliane Kunstmann , Débora Pina , Daniel de Oliveira , Marta Mattoso

Scientists rely on simulations to study natural phenomena. Trusting the simulation results is vital to develop sciences in any field. One approach to build trust is to ensure the reproducibility and traceability of the simulations through…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-21 Paula Olaya , Jay Lofstead , Michela Taufer

Interactive systems are commonly prototyped as web applications. This approach enables studies with functional prototypes on a large scale. However, setting up these studies can be complex due to implementing experiment procedures,…

Human-Computer Interaction · Computer Science 2025-05-20 Florian Lehmann , Daniel Buschek

In the last few years, contributions of the general public in scientific projects has increased due to the advancement of communication and computing technologies. Internet played an important role in connecting scientists and volunteers…

Computers and Society · Computer Science 2017-08-01 Poonam Yadav , Jeremy Cohen , John Darlington

Environmental science is often fragmented: data is collected using mismatched formats and conventions, and models are misaligned and run in isolation. Cloud computing offers a lot of potential in the way of resolving such issues by…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-08-08 Yehia Elkhatib , Gordon S. Blair , Bholanathsingh Surajbali

High-performance computing platforms such as supercomputers have traditionally been designed to meet the compute demands of scientific applications. Consequently, they have been architected as producers and not consumers of data. The Apache…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-02-02 Andre Luckow , Ioannis Paraskevakos , George Chantzialexiou , Shantenu Jha

In a new effort to make our research transparent and reproducible by others, we developed a workflow to run and share computational studies on the public cloud Microsoft Azure. It uses Docker containers to create an image of the application…

Computational Engineering, Finance, and Science · Computer Science 2020-07-24 Olivier Mesnard , Lorena A. Barba

This paper aims to create a transition path from file-based IO to streaming-based workflows for scientific applications in an HPC environment. By using the openPMP-api, traditional workflows limited by filesystem bottlenecks can be overcome…

Increasingly, scientific discovery requires sophisticated and scalable workflows. Workflows have become the ``new applications,'' wherein multi-scale computing campaigns comprise multiple and heterogeneous executable tasks. In particular,…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-26 Shantenu Jha , Vincent R. Pascuzzi , Matteo Turilli

The availability of tera-byte scale experiment data calls for AI driven approaches which automatically discover scientific models from data. Nonetheless, significant challenges present in AI-driven scientific discovery: (i) The annotation…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Md Nasim , Anter El-Azab , Xinghang Zhang , Yexiang Xue

Although Cloud Computing promises to lower IT costs and increase users' productivity in everyday life, the unattractive aspect of this new technology is that the user no longer owns all the devices which process personal data. To lower…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-10-28 Michael Eggert , Roger Häußling , Martin Henze , Lars Hermerschmidt , René Hummen , Daniel Kerpen , Antonio Navarro Pérez , Bernhard Rumpe , Dirk Thißen , Klaus Wehrle