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Related papers: Histopathological Stain Transfer using Style Trans…

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In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng

Transfer learning has emerged as a powerful methodology for adapting pre-trained deep neural networks on image recognition tasks to new domains. This process consists of taking a neural network pre-trained on a large feature-rich source…

Machine Learning · Computer Science 2021-04-27 Francisco Utrera , Evan Kravitz , N. Benjamin Erichson , Rajiv Khanna , Michael W. Mahoney

We propose a fast feed-forward network for arbitrary style transfer, which can generate stylized image for previously unseen content and style image pairs. Besides the traditional content and style representation based on deep features and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Zheng Xu , Michael Wilber , Chen Fang , Aaron Hertzmann , Hailin Jin

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Deep learning advances have revolutionized automated digital pathology analysis. However, differences in staining protocols and imaging conditions can introduce significant color variability. In deep learning, such color inconsistency often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Tianyue Xu , Yanlin Wu , Abhai K. Tripathi , Matthew M. Ippolito , Benjamin D. Haeffele

The different stain styles of cytopathological images have a negative effect on the generalization ability of automated image analysis algorithms. This article proposes a new framework that normalizes the stain style for cytopathological…

Image and Video Processing · Electrical Eng. & Systems 2019-09-12 Xihao Chen , Jingya Yu , Li Chen , Shaoqun Zeng , Xiuli Liu , Shenghua Cheng

Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yiqing Shen , Yulin Luo , Dinggang Shen , Jing Ke

Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types of stains are applied to bring contrast to and highlight various desired histological features. However, the…

Medical Physics · Physics 2022-08-18 Xilin Yang , Bijie Bai , Yijie Zhang , Yuzhu Li , Kevin de Haan , Tairan Liu , Aydogan Ozcan

We propose a novel hematoxylin and eosin (H&E) stain normalization method based on a modified U-Net neural network architecture. Unlike previous deep-learning methods that were often based on generative adversarial networks (GANs), we take…

Image and Video Processing · Electrical Eng. & Systems 2022-11-11 Chi-Chen Lee , Po-Tsun Paul Kuo , Chi-Han Peng

While human observers are able to cope with variations in color and appearance of histological stains, digital pathology algorithms commonly require a well-normalized setting to achieve peak performance, especially when a limited amount of…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Daniel Bug , Steffen Schneider , Anne Grote , Eva Oswald , Friedrich Feuerhake , Julia Schüler , Dorit Merhof

Style transfer is the image synthesis task, which applies a style of one image to another while preserving the content. In statistical methods, the adaptive instance normalization (AdaIN) whitens the source images and applies the style of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Dongki Jung , Seunghan Yang , Jaehoon Choi , Changick Kim

Unsupervised and unpaired domain translation using generative adversarial neural networks, and more precisely CycleGAN, is state of the art for the stain translation of histopathology images. It often, however, suffers from the presence of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Nicolas Brieu , Felix J. Segerer , Ansh Kapil , Philipp Wortmann , Guenter Schmidt

Artistic style transfer is an image synthesis problem where the content of an image is reproduced with the style of another. Recent works show that a visually appealing style transfer can be achieved by using the hidden activations of a…

Computer Vision and Pattern Recognition · Computer Science 2016-12-14 Tian Qi Chen , Mark Schmidt

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Purpose: Neural networks have received recent interest for reconstruction of undersampled MR acquisitions. Ideally network performance should be optimized by drawing the training and testing data from the same domain. In practice, however,…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Salman Ul Hassan Dar , Muzaffer Özbey , Ahmet Burak Çatlı , Tolga Çukur

Image-to-image translation (I2I) methods allow the generation of artificial images that share the content of the original image but have a different style. With the advances in Generative Adversarial Networks (GANs)-based methods, I2I…

Image and Video Processing · Electrical Eng. & Systems 2023-04-07 Igor Zingman , Sergio Frayle , Ivan Tankoyeu , Segrey Sukhanov , Fabian Heinemann

Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yash Sharma , Lubaina Ehsan , Sana Syed , Donald E. Brown

Fine-tuning through knowledge transfer from a pre-trained model on a large-scale dataset is a widely spread approach to effectively build models on small-scale datasets. In this work, we show that a recent adversarial attack designed for…

Machine Learning · Computer Science 2021-04-30 Ting-Wu Chin , Cha Zhang , Diana Marculescu

Traditional staining normalization approaches, e.g. Macenko, typically rely on the choice of a single representative reference image, which may not adequately account for the diverse staining patterns of datasets collected in practical…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Desislav Ivanov , Carlo Alberto Barbano , Marco Grangetto

It is commonly recognized that color variations caused by differences in stains is a critical issue for histopathology image analysis. Existing methods adopt color matching, stain separation, stain transfer or the combination of them to…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hai-Li Ye , Da-Han Wang