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Purpose: The segmentation of brain tumors is one of the most active areas of medical image analysis. While current methods perform superhuman on benchmark data sets, their applicability in daily clinical practice has not been evaluated. In…

Image and Video Processing · Electrical Eng. & Systems 2020-12-17 Sabine Müller , Joachim Weickert , Norbert Graf

Energy-transfer efficiency is an important quantity in plasma-wakefield acceleration, especially for applications that demand high average power. Conventionally, the efficiency is measured using an electron spectrometer; an invasive method…

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

Despite significant medical advancements, cancer remains the second leading cause of death, with over 600,000 deaths per year in the US. One emerging field, pathway analysis, is promising but still relies on manually derived wet lab data,…

Machine Learning · Computer Science 2025-09-17 Rishab Parthasarathy , Achintya Bhowmik

The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule. Here we use a stochastic logistic birth death process to define an organ specific and patient specific…

Tissues and Organs · Quantitative Biology 2014-12-11 Theresa Stocks , Thomas Hillen , Jiafen Gong , Martin Burger

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

In this study, we develop consistent estimators for key parameters that govern the dynamics of tumor cell populations when subjected to pharmacological treatments. While these treatments often lead to an initial reduction in the abundance…

Applications · Statistics 2024-03-21 Kevin Leder , Ruping Sun , Zicheng Wang , Xuanming Zhang

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Computational systems and methods are often being used in biological research, including the understanding of cancer and the development of treatments. Simulations of tumor growth and its response to different drugs are of particular…

This research paper investigates the effectiveness of simple linear models versus complex machine learning techniques in breast cancer diagnosis, emphasizing the importance of interpretability and computational efficiency in the medical…

Machine Learning · Computer Science 2023-06-06 Muhammad Arbab Arshad , Sakib Shahriar , Khizar Anjum

In this paper, a reaction-diffusion system modeling injection of a chemotherapeutic drug on the surface of a living tissue during a treatment for cancer patients is studied. The system describes the interaction of the chemotherapeutic drug…

Analysis of PDEs · Mathematics 2024-08-20 Jeff Morgan , Bao Quoc Tang , Hong-Ming Yin

**Background:** Accurate 3D CT scan segmentation of gastric tumors is pivotal for diagnosis and treatment. The challenges lie in the irregular shapes, blurred boundaries of tumors, and the inefficiency of existing methods. **Purpose:** We…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Zifan Chen , Jiazheng Li , Jie Zhao , Yiting Liu , Hongfeng Li , Bin Dong , Lei Tang , Li Zhang

This paper introduces a computational approach to identify performance constraints in the time-domain, offering a way to design systems in pulse operation. This work presents a comprehensive application of convex optimization to determine…

Information Theory · Computer Science 2025-09-09 Jakub Liska , Lukas Jelinek , Miloslav Capek

Due to the increasing workload of pathologists, the need for automation to support diagnostic tasks and quantitative biomarker evaluation is becoming more and more apparent. Foundation models have the potential to improve generalizability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Till Nicke , Jan Raphael Schaefer , Henning Hoefener , Friedrich Feuerhake , Dorit Merhof , Fabian Kiessling , Johannes Lotz

A method for the optimisation and advanced studies of a laser-plasma electron injector is presented, based on a truncated ionisation injection scheme for high quality beam production. The SMILEI code is used with laser envelope…

A novel and highly efficient computational framework for reconstructing binary-type images suitable for models of various complexity seen in diverse biomedical applications is developed and validated. Efficiency in computational speed and…

Optimization and Control · Mathematics 2024-02-09 Paul R. Arbic , Vladislav Bukshtynov

The performance of image classification methodsheavily relies on the high-quality annotations, which are noteasily affordable, particularly for medical data. To alleviate thislimitation, in this study, we propose a weakly supervised…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Maedeh Sadat Fasihi , Wasfy B. Mikhael

Survival prognosis is crucial for medical informatics. Practitioners often confront small-sized clinical data, especially cancer patient cases, which can be insufficient to induce useful patterns for survival predictions. This study deals…

Machine Learning · Computer Science 2025-01-23 Yonghao Zhao , Changtao Li , Chi Shu , Qingbin Wu , Hong Li , Chuan Xu , Tianrui Li , Ziqiang Wang , Zhipeng Luo , Yazhou He

Accurate segmentation of prostate tumours from PET images presents a formidable challenge in medical image analysis. Despite considerable work and improvement in delineating organs from CT and MR modalities, the existing standards do not…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Shrajan Bhandary , Dejan Kuhn , Zahra Babaiee , Tobias Fechter , Simon K. B. Spohn , Constantinos Zamboglou , Anca-Ligia Grosu , Radu Grosu

The application of heat treatments on 1.3 GHz TESLA type cavities in ultra-high vacuum at 250{\deg}C to 350{\deg}C is called medium temperature or mid-T heat treatment. In various laboratories such treatments on superconducting radio…

Accelerator Physics · Physics 2024-07-18 L. Steder , C. Bate , K. Kasprzak , D. Reschke , L. Trelle , H. Weise , M. Wiencek