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Transport of fast electron in overdense plasmas is of key importance in high energy density physics. However, it is challenging to diagnose the fast electron transport in experiments. In this article, we study coherent transition radiation…

Tissues are fractal due to its self-similar structure, and the fractal dimension change with the abnormalities such as in disease like cancer. The optical imaging of thin slices of tissue using transmission microscopy can produce an…

Biological Physics · Physics 2020-12-29 Liam Elkington , Prakash Adhikari , Prabhakar Pradhan

Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…

Quantitative Methods · Quantitative Biology 2020-08-20 SeyedMehdi Abtahi , Mojtaba Sharifi

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

The limits of TDF (time, dose, and fractionation) and linear quadratic models have been known for a long time. Medical physicists and physicians are required to provide fast and reliable interpretations regarding the delivered doses or any…

Computational Engineering, Finance, and Science · Computer Science 2013-08-28 Cyril Voyant , Daniel Julian , Rudy Roustit , Katia Biffi , Celine Lantieri Marcovici

Purpose: To develop a fast and precise method for searching rectangular regions in brain tumor images. Methods: The authors propose a new method for searching rectangular tumor regions in brain MR images. The proposed method consisted of a…

Image and Video Processing · Electrical Eng. & Systems 2026-01-08 Hidenori Takeshima , Shuki Maruyama

We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…

Medical Physics · Physics 2021-08-11 Samuele Cavinato , Timo Felser , Marco Fusella , Marta Paiusco , Simone Montangero

The primary objective of phase I oncology studies is to establish the safety profile of a new treatment and determine the maximum tolerated dose (MTD). This is motivated by the development of cytotoxic agents based on the underlying…

Applications · Statistics 2023-02-10 Yiding Zhang , Zhixing Xu , Hui Quan , Ji Lin

The advent of ultra-high dose rate irradiation, known as FLASH radiation therapy, has shown promising potential in reducing toxicity while maintaining tumor control. However, the clinical translation of these benefits necessitates efficient…

Medical Physics · Physics 2024-09-19 Viktor Wase , Oscar Widenfalk , Rasmus Nilsson , Claes Fälth , Albin Fredriksson

In this paper, we propose a system to detect brain tumor in 3D MRI brain scans of Flair modality. It performs 2 functions: (a) predicting gray-level and locational distributions of the pixels in the tumor regions and (b) generating tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-03-20 Yanming Sun , Chunyan Wang

The aim is to create a method for accurately estimating the duration of post-cancer treatment, particularly focused on chemotherapy, to optimize patient care and recovery. This initiative seeks to improve the effectiveness of cancer…

Computers and Society · Computer Science 2025-04-24 Joyee Chakraborty , Mazahrul Islam Tohin , Danbir Rashid , Tanjil Ahmed Tanmoy , Md. Jehadul Islam Mony

A holistic simulation framework is established on magnetic hyperthermia modeling to solve the treatment process of tumor, which is surrounded by a healthy tissue block. The interstitial tissue fluid, MNP distribution, temperature profile,…

Purpose. Patients with advanced cancer may undergo multiple lines of treatment, switching therapies as their disease progresses. Motivated by a study of metastatic prostate cancer, we develop a microsimulation framework to study therapy…

We propose a method to incorporate the intensity information of a target lesion on CT scans in training segmentation and detection networks. We first build an intensity-based lesion probability (ILP) function from an intensity histogram of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-13 Seung Yeon Shin , Thomas C. Shen , Ronald M. Summers

We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…

Medical Physics · Physics 2025-09-19 Yoshiki Kubota , Yosuke Nagata , Manabu Tamura , Akimasa Hirata

Survival prediction plays a crucial role in assisting clinicians with the development of cancer treatment protocols. Recent evidence shows that multimodal data can help in the diagnosis of cancer disease and improve survival prediction.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ruiquan Ge , Xiangyang Hu , Rungen Huang , Gangyong Jia , Yaqi Wang , Renshu Gu , Changmiao Wang , Elazab Ahmed , Linyan Wang , Juan Ye , Ye Li

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

Medical Physics · Physics 2023-07-27 Amir Moslemi , Navid Khaledi

Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…

Medical Physics · Physics 2025-10-09 Vivek Maradia , Nick Yue , Adam Molzahn , Jingqian Wang , Mark Pankuch , Serdar Charyyev , Billy W. Loo

Thermally activated delayed fluorescence (TADF) emitters are essential for next-generation, high-efficiency organic light-emitting diodes (OLEDs), yet their rational design is hampered by the high computational cost of accurate…

Cell-based models provide a helpful approach for simulating complex systems that exhibit adaptive, resilient qualities, such as cancer. Their focus on individual cell interactions makes them a particularly appropriate strategy to study the…

Quantitative Methods · Quantitative Biology 2022-11-30 Juan Uriel Legaria-Peña , Félix Sánchez-Morales , Yuriria Cortés-Poza