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The estimation of causal network architectures in the brain is fundamental for understanding cognitive information processes. However, access to the dynamic processes underlying cognition is limited to indirect measurements of the hidden…
The Circle of Willis (CoW) is a critical network of arteries in the brain, often implicated in cerebrovascular pathologies. Voxel-level segmentation is an important first step toward an automated CoW assessment, but a full quantitative…
Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…
Brain imaging data mapping onto human connectome networks enables the investigation of global brain dynamics, where the brain hubs play an essential role in transferring activity between different brain parts. At this scale, the…
Graph Signal Processing (GSP) is a promising framework to analyze multi-dimensional neuroimaging datasets, while taking into account both the spatial and functional dependencies between brain signals. In the present work, we apply…
Despite the recognized importance of the multi-scale spatio-temporal organization of proteins, most computational tools can only access a limited spectrum of time and spatial scales, thereby ignoring the effects on protein behavior of the…
Processing large complex networks recently attracted considerable interest. Complex graphs are useful in a wide range of applications from technological networks to biological systems like the human brain. Sometimes these networks are…
AThe paper gives a few arguments in favour of the use of chain graphs for description of probabilistic conditional independence structures. Every Bayesian network model can be equivalently introduced by means of a factorization formula with…
Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…
Inter-subject registration of cortical areas is necessary in functional imaging (fMRI) studies for making inferences about equivalent brain function across a population. However, many high-level visual brain areas are defined as peaks of…
Data-driven graph learning models a network by determining the strength of connections between its nodes. The data refers to a graph signal which associates a value with each graph node. Existing graph learning methods either use simplified…
Recent studies proposed the use of Total Correlation to describe functional connectivity among brain regions as a multivariate alternative to conventional pair-wise measures such as correlation or mutual information. In this work we build…
Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…
Our goal in this paper is to leverage the potential of the topological signal processing (TSP) framework for analyzing brain networks. Representing brain data as signals over simplicial complexes allows us to capture higher-order…
Network analysis is rapidly becoming a standard tool for studying functional magnetic resonance imaging (fMRI) data. In this framework, different brain areas are mapped to the nodes of a network, whose links depict functional dependencies…
Learning good quality neural graph embeddings has long been achieved by minimizing the point-wise mutual information (PMI) for co-occurring nodes in simulated random walks. This design choice has been mostly popularized by the direct…
A long standing goal in neuroscience has been to elucidate the functional organization of the brain. Within higher visual cortex, functional accounts have remained relatively coarse, focusing on regions of interest (ROIs) and taking the…
Estimated connectomes by the means of neuroimaging techniques have enriched our knowledge of the organizational properties of the brain leading to the development of network-based clinical diagnostics. Unfortunately, to date, many of those…
The architecture of the human connectome supports efficient communication protocols relying either on distances between brain regions or on the intensities of connections. However, none of these protocols combines information about the two…
We present two related methods for deriving connectivity-based brain atlases from individual connectomes. The proposed methods exploit a previously proposed dense connectivity representation, termed continuous connectivity, by first…