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The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…
Graphs are quickly emerging as a leading abstraction for the representation of data. One important application domain originates from an emerging discipline called "connectomics". Connectomics studies the brain as a graph; vertices…
Our understanding of the structure of the brain and its relationships with human traits is largely determined by how we represent the structural connectome. Standard practice divides the brain into regions of interest (ROIs) and represents…
This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…
In this thesis, we present robust and fully-automated methods for the subdivision of the entire human cerebral cortex based on connectivity information. Our contributions are four-fold: First, we propose a clustering approach to delineate a…
The human braingraph, or connectome is a description of the connections of the brain: the nodes of the graph correspond to small areas of the gray matter, and two nodes are connected by an edge if a diffusion MRI-based workflow finds fibers…
The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…
The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years.…
There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…
In statistical connectomics, the quantitative study of brain networks, estimating the mean of a population of graphs based on a sample is a core problem. Often, this problem is especially difficult because the sample or cohort size is…
Currently, connectomes (e.g., functional or structural brain graphs) can be estimated in humans at $\approx 1~mm^3$ scale using a combination of diffusion weighted magnetic resonance imaging, functional magnetic resonance imaging and…
Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…
The human brain is the most complex object of study we encounter today. Mapping the neuronal-level connections between the more than 80 billion neurons in the brain is a hopeless task for science. By the recent advancement of magnetic…
While it is still not possible to describe the neural-level connections of the human brain, we can map the human connectome with several hundred vertices, by the application of diffusion-MRI based techniques. In these graphs, the nodes…
Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…
High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…
Recent advances in molecular and genetic research have identified a diverse range of brain tumor sub-types, shedding light on differences in their molecular mechanisms, heterogeneity, and origins. The present study performs whole-brain…
Anatomical connectivity between different regions in the brain can be mapped to a network representation, the connectome, where the intensities of the links, the weights, influence its structural resilience and the functional processes it…
In mapping the human structural connectome, we are in a very fortunate situation: one can compute and compare graphs, describing the cerebral connections between the very same, anatomically identified small regions of the gray matter among…
Current connectivity diagrams of human brain image data are either overly complex or overly simplistic. In this work we introduce simple yet accurate interactive visual representations of multiple brain image structures and the connectivity…