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In causal inference, whether through randomized controlled trials or observational studies, access to both treated and control units is essential for estimating the effect of a treatment on an outcome of interest. When treatment assignment…

This study introduces an integrated framework for predictive causal inference designed to overcome limitations inherent in conventional single model approaches. Specifically, we combine a Hidden Markov Model (HMM) for spatial health state…

Methodology · Statistics 2025-10-31 Byunghee Lee , Hye Yeon Sin , Joonsung Kang

The scarcity of class-labeled data is a ubiquitous bottleneck in many machine learning problems. While abundant unlabeled data typically exist and provide a potential solution, it is highly challenging to exploit them. In this paper, we…

Machine Learning · Computer Science 2025-07-25 Bing Yu , Ke Sun , He Wang , Zhouchen Lin , Zhanxing Zhu

Learning from positive and unlabeled data (PU learning) is actively researched machine learning task. The goal is to train a binary classification model based on a training dataset containing part of positives which are labeled, and…

Machine Learning · Statistics 2023-12-29 Wojciech Rejchel , Paweł Teisseyre , Jan Mielniczuk

Node classification on graphs is an important research problem with many applications. Real-world graph data sets may not be balanced and accurate as assumed by most existing works. A challenging setting is positive-unlabeled (PU) node…

Machine Learning · Computer Science 2023-10-23 Hansi Yang , Yongqi Zhang , Quanming Yao , James Kwok

Rich Electronic Health Records (EHR), have created opportunities to improve clinical processes using machine learning methods. Prediction of the same patient events at different time horizons can have very different applications and…

Machine Learning · Computer Science 2023-03-07 Hao Liu , Muhan Zhang , Zehao Dong , Lecheng Kong , Yixin Chen , Bradley Fritz , Dacheng Tao , Christopher King

Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep…

Machine Learning · Computer Science 2018-07-02 Veera Raghavendra Chikka , Kamalakar Karlapalem

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

Artificial Intelligence · Computer Science 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Disease name recognition and normalization, which is generally called biomedical entity linking, is a fundamental process in biomedical text mining. Recently, neural joint learning of both tasks has been proposed to utilize the mutual…

Computation and Language · Computer Science 2021-04-22 Shogo Ujiie , Hayate Iso , Shuntaro Yada , Shoko Wakamiya , Eiji Aramaki

Positive Unlabeled (PU) learning is widely used in many applications, where a binary classifier is trained on the datasets consisting of only positive and unlabeled samples. In this paper, we improve PU learning over state-of-the-art from…

Machine Learning · Computer Science 2020-04-22 Liwei Jiang , Dan Li , Qisheng Wang , Shuai Wang , Songtao Wang

In the industrial practice of machine learning and statistical modeling, practitioners often work under the assumption of accessible, static, labeled data for evaluation and training. However, this assumption often deviates from reality,…

Machine Learning · Computer Science 2024-10-14 Kevin Slote , Elaine Lee

Representation learning models for graphs are a successful family of techniques that project nodes into feature spaces that can be exploited by other machine learning algorithms. Since many real-world networks are inherently dynamic, with…

Machine Learning · Computer Science 2020-06-26 Simone Piaggesi , André Panisson

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Positive-unlabeled learning (PU learning) in hyperspectral remote sensing imagery (HSI) is aimed at learning a binary classifier from positive and unlabeled data, which has broad prospects in various earth vision applications. However, when…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Hengwei Zhao , Xinyu Wang , Jingtao Li , Yanfei Zhong

Link prediction on graphs has applications spanning from recommender systems to drug discovery. Temporal link prediction (TLP) refers to predicting future links in a temporally evolving graph and adds additional complexity related to the…

Machine Learning · Computer Science 2025-04-18 Ayan Chatterjee , Barbara Ikica , Babak Ravandi , John Palowitch

While Positive-Unlabeled (PU) learning is vital in many real-world scenarios, its application to graph data still remains under-explored. We unveil that a critical challenge for PU learning on graph lies on the edge heterophily, which…

Machine Learning · Computer Science 2024-06-04 Yuhao Wu , Jiangchao Yao , Bo Han , Lina Yao , Tongliang Liu

Electronic health records (EHRs) contain patients' heterogeneous data that are collected from medical providers involved in the patient's care, including medical notes, clinical events, laboratory test results, symptoms, and diagnoses. In…

Artificial Intelligence · Computer Science 2024-11-12 Shuai Niu , Yunya Song , Qing Yin , Yike Guo , Xian Yang

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

Machine Learning · Computer Science 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

Frontier large language models generate clinically accurate outputs, but their citations are often fabricated. We term this the Provenance Gap. We tested five frontier LLMs across 36 clinician-validated scenarios for three rare…

Planning for a wide range of real-world tasks necessitates to know and write all constraints. However, instances exist where these constraints are either unknown or challenging to specify accurately. A possible solution is to infer the…

Machine Learning · Computer Science 2025-01-17 Baiyu Peng , Aude Billard