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Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

In neuroimaging studies, the human cortex is commonly modeled as a sphere to preserve the topological structure of the cortical surface. Cortical neuroimaging measures hence can be modeled in spherical representation. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

The neonatal cortical surface is known to be affected by preterm birth, and the subsequent changes to cortical organisation have been associated with poorer neurodevelopmental outcomes. Deep Generative models have the potential to lead to…

Neurons and Cognition · Quantitative Biology 2022-06-23 Abdulah Fawaz , Logan Z. Williams , A. David Edwards , Emma Robinson

Cortical surface analysis has gained increased prominence, given its potential implications for neurological and developmental disorders. Traditional vision diffusion models, while effective in generating natural images, present limitations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Zhenshan Xie , Simon Dahan , Logan Z. J. Williams , M. Jorge Cardoso , Emma C. Robinson

We present cortical surface parcellation using spherical deep convolutional neural networks. Traditional multi-atlas cortical surface parcellation requires inter-subject surface registration using geometric features with high processing…

Confirming Alzheimer's disease (AD) typically relies on positron emission tomography (PET), which remains costly and invasive, motivating the use of structural MRI-based prescreening. Deep learning on non-Euclidean manifolds, particularly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Geonwoo Baek , Ikbeom Jang

The study of neurodegenerative diseases relies on the reconstruction and analysis of the brain cortex from magnetic resonance imaging (MRI). Traditional frameworks for this task like FreeSurfer demand lengthy runtimes, while its accelerated…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Rodrigo Santa Cruz , Leo Lebrat , Pierrick Bourgeat , Clinton Fookes , Jurgen Fripp , Olivier Salvado

State-of-the-art methods for quantifying wear in cylinder liners of large internal combustion engines require disassembly and cutting of the liner. This is followed by laboratory-based high-resolution microscopic surface depth measurement…

The conventional CNN, widely used for two-dimensional images, however, is not directly applicable to non-regular geometric surface, such as a cortical thickness. We propose Geometric CNN (gCNN) that deals with data representation over a…

Neural and Evolutionary Computing · Computer Science 2017-08-03 Si-Baek Seong , Chongwon Pae , Hae-Jeong Park

Automated surface segmentation is important and challenging in many medical image analysis applications. Recent deep learning based methods have been developed for various object segmentation tasks. Most of them are a classification based…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Leixin Zhou , Xiaodong Wu

Accurate cortical surface reconstruction from magnetic resonance imaging (MRI) data is crucial for reliable neuroanatomical analyses. Current methods have to contend with complex cortical geometries, strict topological requirements, and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Kaveh Moradkhani , R Jarrett Rushmore , Sylvain Bouix

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Real cortical tissue curves and folds according to experimental data. However, our current simulations only use unfolded cortical layers. This project extends the cortical slice model in order to be able to specify arbitrary curvatures to…

Neurons and Cognition · Quantitative Biology 2014-05-15 Jintao Long , Richard Tomsett , Marcus Kaiser

The detection of heterogeneous mental disorders based on brain readouts remains challenging due to the complexity of symptoms and the absence of reliable biomarkers. This paper introduces CAM (Cortical Anomaly Detection through Masked Image…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Hao-Chun Yang , Ole Andreassen , Lars Tjelta Westlye , Andre F. Marquand , Christian F. Beckmann , Thomas Wolfers

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

Spinal cord segmentation is clinically relevant and is notably used to compute spinal cord cross-sectional area (CSA) for the diagnosis and monitoring of cord compression or neurodegenerative diseases such as multiple sclerosis. While…

To achieve fast, robust, and accurate reconstruction of the human cortical surfaces from 3D magnetic resonance images (MRIs), we develop a novel deep learning-based framework, referred to as SurfNN, to reconstruct simultaneously both inner…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Hao Zheng , Hongming Li , Yong Fan