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The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…

From interacting cellular components to networks of neurons and neural systems, interconnected units comprise a fundamental organizing principle of the nervous system. Understanding how their patterns of connections and interactions give…

Neurons and Cognition · Quantitative Biology 2018-08-01 Danielle S. Bassett , Perry Zurn , Joshua I. Gold

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

Network science has been applied widely to study brain network organization, especially at the meso-scale, where nodes represent brain areas and edges reflect interareal connectivity inferred from imaging or tract-tracing data. While this…

Neurons and Cognition · Quantitative Biology 2025-08-26 Richard Betzel , Caio Seguin , Maria Grazia Puxeddu

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

Neurons and Cognition · Quantitative Biology 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent…

Neurons and Cognition · Quantitative Biology 2016-12-26 Danielle S. Bassett , Ankit N. Khambhati , Scott T. Grafton

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

For constructing neuronal network models computational neuroscientists have access to wide-ranging anatomical data that nevertheless tend to cover only a fraction of the parameters to be determined. Finding and interpreting the most…

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

Recent advances in network science, applied to \textit{in vivo} brain recordings, have paved the way for better understanding of the structure and function of the brain. However, despite its obvious usefulness in neuroscience, traditional…

Neurons and Cognition · Quantitative Biology 2025-02-03 Vesna Vuksanovic

Endowing brain anatomy, dynamics, and function with a network structure is becoming standard in neuroscience. In its simplest form, a network is a collection of units and relationships between them. The pattern of relations among the units…

Neurons and Cognition · Quantitative Biology 2025-07-22 David Papo , Javier M. Buldú

Although social neuroscience is concerned with understanding how the brain interacts with its social environment, prevailing research in the field has primarily considered the human brain in isolation, deprived of its rich social context.…

Social and Information Networks · Computer Science 2020-02-13 Elisa C. Baek , Mason A. Porter , Carolyn Parkinson

The field of neuroscience is facing an unprecedented expanse in the volume and diversity of available data. Traditionally, network models have provided key insights into the structure and function of the brain. With the advent of big data…

Neurons and Cognition · Quantitative Biology 2018-02-14 Michael Vaiana , Sarah Muldoon

Connectomics is a field of neuroscience that analyzes neuronal connections. A connectome is a complete map of a neuronal system, comprising all neuronal connections between its structures. The term "connectome" is close to the word "genome"…

Networks of interconnected nodes have long played a key role in Cognitive Science, from artificial neural net- works to spreading activation models of semantic mem- ory. Recently, however, a new Network Science has been developed, providing…

Understanding brain connectivity in a network-theoretic context has shown much promise in recent years. This type of analysis identifies brain organisational principles, bringing a new perspective to neuroscience. At the same time, large…

Neural and Evolutionary Computing · Computer Science 2016-11-28 Sarah Parisot , Jonathan Passerat-Palmbach , Markus D. Schirmer , Boris Gutman

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Network neuroscience represents the brain as a collection of regions and inter-regional connections. Given its ability to formalize systems-level models, network neuroscience has generated unique explanations of neural function and…

Neurons and Cognition · Quantitative Biology 2019-11-13 Maxwell A. Bertolero , Danielle S. Bassett

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

Human learning is a complex phenomenon that requires adaptive processes across a range of temporal and spacial scales. While our understanding of those processes at single scales has increased exponentially over the last few years, a…

Neurons and Cognition · Quantitative Biology 2016-09-08 Marcelo G. Mattar , Danielle S. Bassett
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