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The ongoing COVID-19 pandemic is challenging every part of society. From a scientific point of view the first major task is to predict the dynamics of the pandemic, allowing governments to allocate proper resources and measures to fight it,…

Populations and Evolution · Quantitative Biology 2020-09-29 Heinrich Stolz , Dirk Semkat , Peter Grünwald

At the onset of the Covid-19 pandemic, a number of non-pharmaceutical interventions have been implemented in order to reduce transmission, thus leading to multiple phases of transmission. The disease reproduction number $R_t$, a way of…

Applications · Statistics 2023-05-03 Petros Barmpounakis , Nikolaos Demiris

The evolution of the COVID-19 epidemic has been accompanied by accumulating evidence on the underlying epidemiological parameters. Hence there is potential for models providing mid-term forecasts of the epidemic trajectory using such…

Applications · Statistics 2020-11-10 Peter Congdon

By the end of July 2020, the COVID-19 pandemic had infected more than seventeen million people and had spread to almost all countries worldwide. In response, many countries all over the world have used different methods to reduce the…

Physics and Society · Physics 2020-08-21 Hilla De-Leon , Francesco Pederiva

We propose an SEIR-type meta-population model to simulate and monitor the Covid-19 epidemic evolution. The basic model consists of seven compartments, namely susceptible (S), exposed (E), three infective classes, recovered (R), and deceased…

Populations and Evolution · Quantitative Biology 2020-11-18 Vinicius V. L. Albani , Roberto M. Velho , Jorge P. Zubelli

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

In the absence of other tools, monitoring the effects of protective measures, including social distancing and forecasting the outcome of outbreaks is of immense interest. Real-time data is noisy and very often hampered by systematic errors…

Populations and Evolution · Quantitative Biology 2020-08-11 Gabor Vattay

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Classical epidemiological models assume homogeneous populations. There have been important extensions to model heterogeneous populations, when the identity of the sub-populations is known, such as age group or geographical location. Here,…

Machine Learning · Computer Science 2023-02-10 Roberto Vega , Zehra Shah , Pouria Ramazi , Russell Greiner

I use a very simple deterministic model for the spread of Covid-19 in a large population. Using this to compare the relative decay of the number of deaths per day between different regions in Italy, Spain and England, each applying in…

Populations and Evolution · Quantitative Biology 2020-05-26 Robert S Thorne

The impact of mitigation or control measures on an epidemics can be estimated by fitting the parameters of a compartmental model to empirical data, and running the model forward with modified parameters that account for a specific measure.…

Populations and Evolution · Quantitative Biology 2020-04-10 Jacopo Grilli , Matteo Marsili , Guido Sanguinetti

This paper considers a stochastic SIR (susceptible$\to$infective$\to$removed) epidemic model in which individuals may make infectious contacts in two ways, both within `households' (which for ease of exposition are assumed to have equal…

Probability · Mathematics 2015-03-13 Frank Ball , David Sirl , Pieter Trapman

Some basic facts that enable or constrain efforts to "flatten the curve" by non-pharmaceutical interventions (NPI) are summarized and placed in the current context of the COVID-19 epidemic. Analytical formulas are presented for a simple…

Populations and Evolution · Quantitative Biology 2020-04-14 Michael Nikolaou

Many models of epidemic spread have a common qualitative structure. The numbers of infected individuals during the initial stages of an epidemic can be well approximated by a branching process, after which the proportion of individuals that…

Probability · Mathematics 2013-01-16 A. D. Barbour , Gesine Reinert

We have established a novel mathematical model that considers various aspects of the spreading of the virus, including, the transmission based on being in the latent period, environment to human transmission, governmental decisions, and…

Quantitative Methods · Quantitative Biology 2020-08-31 Kamran Soltani , Ghader Rezazadeh

In this paper we analyze the effects of commuting and social inequalities for the epidemic development of the novel coronavirus (COVID-19). With this aim we consider a SEIRD (susceptible, exposed, infected, recovered and dead by disease)…

Populations and Evolution · Quantitative Biology 2020-08-18 João A. M. Gondim , Thiago Yukio Tanaka

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

In a given country, the cumulative death toll of the first wave of the COVID-19 epidemic follows a sigmoid curve as a function of time. In most cases, the curve is well described by the Gompertz function, which is characterized by two…

Populations and Evolution · Quantitative Biology 2020-08-07 Kristoffer Rypdal , Martin Rypdal

Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

Populations and Evolution · Quantitative Biology 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

We study the problem of a policymaker who aims at taming the spread of an epidemic while minimizing its associated social costs. The main feature of our model lies in the fact that the disease's transmission rate is a diffusive stochastic…

Optimization and Control · Mathematics 2020-11-04 Salvatore Federico , Giorgio Ferrari