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This paper describes how realistic neuromorphic networks can have their connectivity fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the two-dimensional…

Disordered Systems and Neural Networks · Physics 2007-05-23 Luciano da Fontoura Costa , Marconi Soares Barbosa

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

Neurons and Cognition · Quantitative Biology 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity. Using a modified resting-state paradigm to drive subjects' attention, we provide…

Neurons and Cognition · Quantitative Biology 2012-11-21 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Ramón Leiguarda , Mariano Sigman

Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

Applications · Statistics 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

Electrical brain stimulation is currently being investigated as a therapy for neurological disease. However, opportunities to optimize such therapies are challenged by the fact that the beneficial impact of focal stimulation on both…

Recent studies have been using graph theoretical approaches to model complex networks (such as social, infrastructural or biological networks), and how their hardwired circuitry relates to their dynamic evolution in time. Understanding how…

Neurons and Cognition · Quantitative Biology 2015-07-17 Anca Radulescu

Network architecture forms a critical constraint on neuronal function. Here we examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal…

Neurons and Cognition · Quantitative Biology 2016-08-02 Laura Wiles , Shi Gu , Fabio Pasqualetti , Danielle S. Bassett , David F. Meaney

Autism Spectrum Disorder (ASD) is characterized by an altered phenotype in social interaction and communication. Additionally, autism typically manifests differently in females as opposed to males: a phenomenon that has likely led to…

Neurons and Cognition · Quantitative Biology 2024-05-08 Michelle McCleod , Sean Borneman , Evie Malaia

The neuronal circuit that controls obsessive and compulsive behaviors involves a complex network of brain regions (some with known involvement in reward processing). Among these are cortical regions, the striatum and the thalamus (which…

Neurons and Cognition · Quantitative Biology 2015-12-17 Anca Radulescu , Rachel Marra

Several studies have used structural correlation networks, derived from anatomical covariance of brain regions, to analyze neurologic changes associated with multiple sclerosis, schizophrenia and breast cancer [1][2]. Graph-theoretical…

Quantitative Methods · Quantitative Biology 2019-04-25 Muhammad Usman Sadiq , Diana Svaldi , Trey Shenk , Evan Breedlove , Victoria Poole , Greg Tamer , Kausar Abbas , Thomas Talavage

Controllability of complex networks arises in many technological problems involving social, financial, road, communication, and smart grid networks. In many practical situations, the underlying topology might change randomly with time, due…

Systems and Control · Computer Science 2020-01-08 Fernando Gama , Elvin Isufi , Alejandro Ribeiro , Geert Leus

Volitional memory control supports adaptive cognition by enabling intentional suppression of goal-irrelevant, interfering memories and recall of goal-relevant memories. Neural mechanisms of suppression and recall have been studied largely…

Neurons and Cognition · Quantitative Biology 2026-04-14 Shruti Kinger , Mrinmoy Chakrabarty

In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

Neurons and Cognition · Quantitative Biology 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Controlling complex networks is of paramount importance in science and engineering. Despite the recent development of structural-controllability theory, we continue to lack a framework to control undirected complex networks, especially…

Physics and Society · Physics 2013-10-23 Zhengzhong Yuan , Chen Zhao , Zengru Di , Wen-Xu Wang , Ying-Cheng Lai

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

Neurons and Cognition · Quantitative Biology 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Brain disorders are an umbrella term for a group of neurological and psychiatric conditions that have a major effect on thinking, feeling, and acting. These conditions encompass a wide range of conditions. The illnesses in question pose…

Neurons and Cognition · Quantitative Biology 2025-11-11 Aniruddha Saha , Soujanya Hazra , Sanjay Ghosh

The segregated regions of the mammalian cerebral cortex and thalamus form an extensive and complex network, whose structure and function are still only incompletely understood. The present article describes an application of the concepts of…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luciano da Fontoura Costa , Olaf Sporns

Understanding brain dynamics and functions critically depends on knowledge of the network connectivity among neurons. However, the complexity of brain structural connectivity, coupled with continuous modifications driven by synaptic…

Neurons and Cognition · Quantitative Biology 2025-07-04 Kai Chen , Mingzhang Wang , Songting Li , Douglas Zhou

The brain's structural and functional systems, protein-protein interaction, and gene networks are examples of biological systems that share some features of complex networks, such as highly connected nodes, modularity, and small-world…

Autism spectrum disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a robust, objective, and efficient diagnostic.…

Neurons and Cognition · Quantitative Biology 2024-03-04 Annie Adhikary
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