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Electronic health records (EHRs) include simple features like patient age together with more complex data like care history that are informative but not easily represented as individual features. To better harness such data, we developed an…

Artificial Intelligence · Computer Science 2023-02-14 Jacqueline K. Kueper , Jennifer Rayner , Daniel J. Lizotte

The integration of clinical data offers significant potential for the development of personalized medicine. However, its use is severely restricted by the General Data Protection Regulation (GDPR), especially for small cohorts with rare…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-30 Simon Süwer , Mai Khanh Mai , Christoph Klein , Nicola Götzenberger , Denis Dalić , Andreas Maier , Jan Baumbach

Background: Electronic health records (EHRs) enable machine learning for diagnosis, prognosis, and clinical decision support. However, EHR standards vary by country and hospital, making records often incompatible. This limits large-scale…

Information Retrieval · Computer Science 2026-03-27 Jiawei Zhao , Md Shamim Ahmed , Nicolai Dinh Khang Truong , Verena Schuster , Rudolf Mayer , Richard Röttger

The link between in vitro hERG ion channel inhibition and subsequent in vivo QT interval prolongation, a critical risk factor for the development of arrythmias such as Torsade de Pointes, is so well established that in vitro hERG activity…

Machine Learning · Computer Science 2024-08-08 Gregory W. Kyro , Matthew T. Martin , Eric D. Watt , Victor S. Batista

We developed an explainable artificial intelligence (AI) early warning score (xAI-EWS) system for early detection of acute critical illness. While maintaining a high predictive performance, our system explains to the clinician on which…

Background: Electronic Health Records (EHRs) contain rich information of patients' health history, which usually include both structured and unstructured data. There have been many studies focusing on distilling valuable information from…

Machine Learning · Computer Science 2021-11-10 Ziyi Liu , Jiaqi Zhang , Yongshuai Hou , Xinran Zhang , Ge Li , Yang Xiang

A promising application of AI to healthcare is the retrieval of information from electronic health records (EHRs), e.g. to aid clinicians in finding relevant information for a consultation or to recruit suitable patients for a study. This…

Computation and Language · Computer Science 2020-11-02 Claudia Schulz , Josh Levy-Kramer , Camille Van Assel , Miklos Kepes , Nils Hammerla

The potential presented by Artificial Intelligence (AI) for healthcare has long been recognised by the technical community. More recently, this potential has been recognised by policymakers, resulting in considerable public and private…

Artificial Intelligence · Computer Science 2021-04-15 Jessica Morley , Caroline Morton , Kassandra Karpathakis , Mariarosaria Taddeo , Luciano Floridi

Personal Health Records (PHR) emerge as an alternative to integrate patient's health information to give a global view of patients' status. However, integration is not a trivial feature when dealing with a variety electronic health systems…

Computers and Society · Computer Science 2016-09-14 Jesús Romero , Pablo López , José Luis Vázquez Noguera , Cristian Cappo , Diego P. Pinto-Roa , Cynthia Villalba

In the context of collaborative AI research and development projects, it would be ideal to have self-contained encapsulated algorithms that can be easily shared between different parties, executed and validated on data at different sites,…

Software Engineering · Computer Science 2025-09-12 Hans Meine , Yongli Mou , Guido Prause , Horst Hahn

The proliferation of Large Language Models (LLMs) has led to a burgeoning ecosystem of specialized, domain-specific models. While this rapid growth accelerates innovation, it has simultaneously created significant challenges in model…

Software Engineering · Computer Science 2026-04-16 Pengyue Yang , Haolin Jin , Qingwen Zeng , Jiawen Wen , Harry Rao , Huaming Chen

Clinical prediction from structured electronic health records (EHRs) is challenging due to high dimensionality, heterogeneity, class imbalance, and distribution shift. While tabular in-context learning (TICL) and retrieval-augmented methods…

Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a…

Computers and Society · Computer Science 2017-11-20 Anand Avati , Kenneth Jung , Stephanie Harman , Lance Downing , Andrew Ng , Nigam H. Shah

Question Answering (QA) systems on patient-related data can assist both clinicians and patients. They can, for example, assist clinicians in decision-making and enable patients to have a better understanding of their medical history.…

Machine Learning · Computer Science 2023-11-09 Jayetri Bardhan , Kirk Roberts , Daisy Zhe Wang

Electronic Health Record (EHR) data encompass diverse modalities -- text, images, and medical codes -- that are vital for clinical decision-making. To process these complex data, multimodal AI (MAI) has emerged as a powerful approach for…

Machine Learning · Computer Science 2026-03-03 Nikkie Hooman , Zhongjie Wu , Eric C. Larson , Mehak Gupta

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

When most patients visit physicians in a clinic or a hospital, they are asked about their medical history and related medical tests' results which might not exist or might simply have been lost over time. In emergency situations, many…

Computers and Society · Computer Science 2016-05-12 Nael A. H AbuOun , Ayman Abdel-Hamid , Mohamad Abou El-Nasr

The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…

With the advancements in computer technology, there is a rapid development of intelligent systems to understand the complex relationships in data to make predictions and classifications. Artificail Intelligence based framework is rapidly…

Machine Learning · Computer Science 2021-07-30 G Jignesh Chowdary , Suganya G , Premalatha M , Asnath Victy Phamila Y , Karunamurthy K

Predicting long-term loan defaults is hard because borrower behavior often changes and data distributions shift over time. This paper presents HYDRA-EI, a hybrid ensemble incremental learning framework. It uses several stages of feature…

Machine Learning · Computer Science 2025-10-10 Jiajing Wang
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