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In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

Neurons and Cognition · Quantitative Biology 2019-03-29 Peter Helfer , Thomas R. Shultz

Place cells in the rat hippocampus play a key role in creating the animal's internal representation of the world. During active navigation, these cells spike only in discrete locations, together encoding a map of the environment.…

Neurons and Cognition · Quantitative Biology 2016-03-22 Yuri Dabaghian

Most models of neurons incorporate a capacitor to account for the marked capacitive behavior exhibited by the cell membrane. However, such capacitance is widely considered constant, thereby neglecting the possible effects of time-dependent…

Neurons and Cognition · Quantitative Biology 2025-12-29 Matías Courdurier , Leonel E. Medina , Esteban Paduro

Causal ordering of key events in the cell cycle is essential for proper functioning of an organism. Yet, it remains a mystery how a specific temporal program of events is maintained despite ineluctable stochasticity in the biochemical…

Molecular Networks · Quantitative Biology 2017-03-30 Farshid Jafarpour , Michael Vennettilli , Srividya Iyer-Biswas

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Working memory requires the brain to maintain information from the recent past to guide ongoing behavior. Neurons can contribute to this capacity by slowly integrating their inputs over time, creating persistent activity that outlasts the…

Neurons and Cognition · Quantitative Biology 2025-11-20 Nicoas Zucchet , Qianqian Feng , Axel Laborieux , Friedemann Zenke , Walter Senn , João Sacramento

Certain biological neurons demonstrate a remarkable capability to optimally compress the history of sensory inputs while being maximally informative about the future. In this work, we investigate if the same can be said of artificial…

Machine Learning · Computer Science 2020-02-12 Zhe Dong , Deniz Oktay , Ben Poole , Alexander A. Alemi

Animals exploit time to survive in the world. Temporal information is required for higher-level cognitive abilities such as planning, decision making, communication, and effective cooperation. Since time is an inseparable part of cognition,…

Artificial Intelligence · Computer Science 2020-12-29 Hamit Basgol , Inci Ayhan , Emre Ugur

Memory replay may be key to learning in biological brains, which manage to learn new tasks continually without catastrophically interfering with previous knowledge. On the other hand, artificial neural networks suffer from catastrophic…

Machine Learning · Computer Science 2022-01-06 Haitz Sáez de Ocáriz Borde

Memory is a complex phenomenon that involves several distinct mechanisms. These mechanisms operate at different spatial and temporal levels. This chapter focuses on the theoretical framework and the mathematical models that have been…

Neurons and Cognition · Quantitative Biology 2021-12-22 Stefano Fusi

The vast majority of natural sensory data is temporally redundant. Video frames or audio samples which are sampled at nearby points in time tend to have similar values. Typically, deep learning algorithms take no advantage of this…

Neural and Evolutionary Computing · Computer Science 2017-06-14 Peter O'Connor , Efstratios Gavves , Max Welling

Space is represented in the mammalian brain by the activity of hippocampal place cells as well as in their spike-timing correlations. Here we propose a theory how this temporal code is transformed to spatial firing rate patterns via…

Neurons and Cognition · Quantitative Biology 2017-08-02 Mauro M. Monsalve-Mercado , Christian Leibold

Because organisms are able to sense its passage, it is perhaps tempting to treat time as a sensory modality, akin to vision or audition. Indeed, certain features of sensory estimation, such as Weber's law, apply to timing and sensation…

Neurons and Cognition · Quantitative Biology 2025-04-01 Caroline Haimerl , Filipe S. Rodrigues , Joseph J. Paton

We consider the general problem of modeling temporal data with long-range dependencies, wherein new observations are fully or partially predictable based on temporally-distant, past observations. A sufficiently powerful temporal model…

Reasoning about time is of fundamental importance. Many facts are time-dependent. For example, athletes change teams from time to time, and different government officials are elected periodically. Previous time-dependent question answering…

Computation and Language · Computer Science 2023-06-28 Qingyu Tan , Hwee Tou Ng , Lidong Bing

We propose a new self-organizing mechanism behind the emergence of memory in which temporal sequences of stimuli are transformed into spatial activity patterns. In particular, the memory emerges despite the absence of temporal correlations…

Disordered Systems and Neural Networks · Physics 2009-11-07 Konstantin Klemm , Preben Alstrom

In this work we present a novel recurrent neural network architecture designed to model systems characterized by multiple characteristic timescales in their dynamics. The proposed network is composed by several recurrent groups of neurons…

Neural and Evolutionary Computing · Computer Science 2017-01-19 Filippo Maria Bianchi , Michael Kampffmeyer , Enrico Maiorino , Robert Jenssen

We present a comprehensive, novel framework for understanding how the neocortex, including the thalamocortical loops through the deep layers, can support a temporal context representation in the service of predictive learning. Many have…

Neurons and Cognition · Quantitative Biology 2014-07-15 Randall C. O'Reilly , Dean Wyatte , John Rohrlich

The brain is very often viewed as a network, be it at small scale made of cells, mostly neurons, or at larger scale made of neuronal assemblies. Here we introduce a conjecture, in the spirit of a philosophical though experiment, which…

Neurons and Cognition · Quantitative Biology 2025-12-24 Julien Lagarde

Tasks in which rewards depend upon past information not available in the current observation set can only be solved by agents that are equipped with short-term memory. Usual choices for memory modules include trainable recurrent hidden…

Machine Learning · Computer Science 2024-12-18 Kevin McKee