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Over the last ten years, developments in whole-brain microscopy now allow for high-resolution imaging of intact brains of small rodents such as mice. These complex images contain a wealth of information, but many neuroscience laboratories…

Neurons and Cognition · Quantitative Biology 2021-02-24 Adam L Tyson , Troy W Margrie

Deep learning models have become the dominant method for medical image segmentation. However, they often struggle to be generalisable to unknown tasks involving new anatomical structures, labels, or shapes. In these cases, the model needs…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Jing Xu

The medical image analysis field has traditionally been focused on the development of organ-, and disease-specific methods. Recently, the interest in the development of more 20 comprehensive computational anatomical models has grown,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Juan J. Cerrolaza , Mirella Lopez-Picazo , Ludovic Humbert , Yoshinobu Sato , Daniel Rueckert , Miguel Angel Gonzalez Ballester , Marius George Linguraru

Large-scale medical imaging datasets have accelerated deep learning (DL) for medical image analysis. However, the large scale of these datasets poses a challenge for researchers, resulting in increased storage and bandwidth requirements for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Pranav Kulkarni , Adway Kanhere , Eliot Siegel , Paul H. Yi , Vishwa S. Parekh

Bio image analysis has recently become one keystone of biological research but biologists tend to get lost in a plethora of available software and the way to adjust available tools to their own image analysis problem. We present BIII,…

Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Data augmentation is one of the most effective techniques to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability in medical image analysis, it is frequently underutilized. This…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Adam Tupper , Christian Gagné

Automated brain tumor segmentation methods have become well-established and reached performance levels offering clear clinical utility. These methods typically rely on four input magnetic resonance imaging (MRI) modalities: T1-weighted…

Modern data collection in many data paradigms, including bioinformatics, often incorporates multiple traits derived from different data types (i.e. platforms). We call this data multi-block, multi-view, or multi-omics data. The emergent…

Methodology · Statistics 2024-01-18 Jack B. Prothero , Meilei Jiang , Jan Hannig , Quoc Tran-Dinh , Andrew Ackerman , J. S. Marron

Accurate segmentation of anatomical structures and abnormalities in medical images is crucial for computer-aided diagnosis and analysis. While deep learning techniques excel at this task, their computational demands pose challenges.…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Hamid Alinejad-Rokny , Arcot Sowmya , Imran Razzak

While computer vision has proven valuable for medical image segmentation, its application faces challenges such as limited dataset sizes and the complexity of effectively leveraging unlabeled images. To address these challenges, we present…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Zhaoshan Liua , Qiujie Lv , Chau Hung Lee , Lei Shen

To build a robust and practical content-based image retrieval (CBIR) system that is applicable to a clinical brain MRI database, we propose a new framework -- Disease-oriented image embedding with pseudo-scanner standardization (DI-PSS) --…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Hayato Arai , Yuto Onga , Kumpei Ikuta , Yusuke Chayama , Hitoshi Iyatomi , Kenichi Oishi

A traditional database systems is organized around a single data model that determines how data can be organized, stored and manipulated. But the vision of this paper is to develop new principles and techniques to manage multiple data…

Databases · Computer Science 2016-12-26 Jiaheng Lu , Zhen Hua Liu , Pengfei Xu , Chao Zhang

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

Brain-computer interfaces (BCIs) are enabling a range of new possibilities and routes for augmenting human capability. Here, we propose BCIs as a route towards forms of computation, i.e. computational imaging, that blend the brain with…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Gao Wang , Daniele Faccio

Brain tumor segmentation intends to delineate tumor tissues from healthy brain tissues. The tumor tissues include necrosis, peritumoral edema, and active tumor. In contrast, healthy brain tissues include white matter, gray matter, and…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Snehal Rajput , Mehul S Raval

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Huimin Cheng , Xiaowei Yu , Shushan Wu , Luyang Fang , Chao Cao , Jing Zhang , Tianming Liu , Dajiang Zhu , Wenxuan Zhong , Ping Ma

The past decade has witnessed order of magnitude increases in computing power, data storage capacity and network speed, giving birth to applications which may handle large data volumes of increased complexity, distributed over the Internet.…

Databases · Computer Science 2007-05-23 F Estrella , C del Frate , T Hauer , R McClatchey , M Odeh , D Rogulin , S R Amendolia , D Schottlander , T Solomonides , R Warren

The integration of deep learning in medical imaging has shown great promise for enhancing diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to the inherent…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Yixin Chen , Lin Gao , Yajuan Gao , Rui Wang , Jingge Lian , Xiangxi Meng , Yanhua Duan , Leiying Chai , Hongbin Han , Zhaoping Cheng , Zhaoheng Xie

In this paper we will focus on the potential and on the challenges associated with the development of an integrated brain and spinal cord modelling framework for processing MR neuroimaging data. The aim of the work is to explore how a…

Computer Vision and Pattern Recognition · Computer Science 2017-07-06 Claudia Blaiotta , Patrick Freund , M. Jorge Cardoso , John Ashburner