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Purpose: Multiple Coulomb scattering (MCS) poses a challenge in proton CT (pCT) image reconstruction. The assumption of straight paths is replaced with Bayesian models of the most likely path (MLP). Current MLP-based pCT reconstruction…

Medical Physics · Physics 2020-02-10 Mark Brooke , Scott Penfold

This is a review paper on some of the physics, modeling, and iterative algorithms in proton computed tomography (pCT) image reconstruction. The primary challenge in pCT image reconstruction lies in the degraded spatial resolution resulting…

Medical Physics · Physics 2015-10-30 Scott Penfold , Yair Censor

Particle track reconstruction is the most computationally intensive process in nuclear physics experiments. Traditional algorithms use a combinatorial approach that exhaustively tests track measurements ("hits") to identify those that form…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Polykarpos Thomadakis , Angelos Angelopoulos , Gagik Gavalian , Nikos Chrisochoides

Three-dimensional particle reconstruction with limited two-dimensional projections is an under-determined inverse problem that the exact solution is often difficult to be obtained. In general, approximate solutions can be obtained by…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Qi Gao , Shaowu Pan , Hongping Wang , Runjie Wei , Jinjun Wang

Proton radiography is a technique extensively used to resolve magnetic field structures in high energy density plasmas, revealing a whole variety of interesting phenomena such as magnetic reconnection and collisionless shocks found in…

Deep neural networks (DNN) have achieved remarkable success in various fields, including computer vision and natural language processing. However, training an effective DNN model still poses challenges. This paper aims to propose a method…

Machine Learning · Computer Science 2024-07-03 Hejie Ying , Mengmeng Song , Yaohong Tang , Shungen Xiao , Zimin Xiao

We propose a physics-guided neural network (PGNN) framework for constructing nucleon-nucleon inverse potentials based on inverse scattering theory. The framework integrates the Phase Function Method (PFM) with a two-stage supervised…

Nuclear Theory · Physics 2025-09-03 Ayushi Awasthi , Anil Khachi , M. R. Ganesh Kumar , O. S. K. S. Sastri

Machine learning (ML) is revolutionizing protein structural analysis, including an important subproblem of predicting protein residue contact maps, i.e., which amino-acid residues are in close spatial proximity given the amino-acid sequence…

Quantitative Methods · Quantitative Biology 2022-12-23 Kuang Liu , Rajiv K. Kalia , Xinlian Liu , Aiichiro Nakano , Ken-ichi Nomura , Priya Vashishta , Rafael Zamora-Resendizc

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

In this paper, we explore a novel method for tomographic image reconstruction in the field of SPECT imaging. Deep Learning methodologies and more specifically deep convolutional neural networks (CNN) are employed in the new reconstruction…

Machine Learning · Computer Science 2020-10-20 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Very deep Convolutional Neural Networks (CNNs) have greatly improved the performance on various image restoration tasks. However, this comes at a price of increasing computational burden, hence limiting their practical usages. We observe…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Ke Yu , Xintao Wang , Chao Dong , Xiaoou Tang , Chen Change Loy

We propose a modified normalized direct linear transform (DLT) algorithm for solving the perspective-n-point (PnP) problem with much better behavior than the conventional DLT. The modification consists of analytically weighting the…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Sébastien Henry , John A. Christian

Malignant pleural mesothelioma (MPM) is the most common form of mesothelioma. To assess response to treatment, tumor measurements are acquired and evaluated based on a patient's longitudinal computed tomography (CT) scans. Tumor volume,…

Proton Computed Tomography (CT) is a prototype imaging modality for the reconstruction of the Relative Stopping Power of a patient, for more accurate calculations of the dose distributions in proton therapy dose planning. The measurements…

Although deeper and larger neural networks have achieved better performance, the complex network structure and increasing computational cost cannot meet the demands of many resource-constrained applications. Existing methods usually choose…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Yingcheng Su , Shunfeng Zhou , Yichao Wu , Tian Su , Ding Liang , Jiaheng Liu , Dixin Zheng , Yingxu Wang , Junjie Yan , Xiaolin Hu

This article presents a physics-informed deep learning method for the quantitative estimation of the spatial coordinates of gamma interactions within a monolithic scintillator, with a focus on Positron Emission Tomography (PET) imaging. A…

Understanding the mechanisms underlying crystal formation is crucial. For most systems, crystallization typically goes through a nucleation process that involves dynamics that happen at short time and length scales. Due to this, molecular…

Statistical Mechanics · Physics 2025-11-04 Steven W. Hall , Porhouy Minh , Sapna Sarupria

Objective. Proton beams enable localized dose delivery. Accurate range estimation is essential, but planning still relies on X-ray CT, which introduces uncertainty in stopping power and range. Proton CT measures water equivalent thickness…

Medical Physics · Physics 2025-09-15 Atiq Ur Rahman , Chun-Chieh Wang , Shu-Wei Wu , Tsi-Chian Chao , I-Chun Cho

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Probabilistic power flow (PPF) plays a critical role in power system analysis. However, the high computational burden makes it challenging for the practical implementation of PPF. This paper proposes a model-based deep learning approach to…

Signal Processing · Electrical Eng. & Systems 2019-09-17 Yan Yang , Zhifang Yang , Juan Yu , Baosen Zhang
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