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Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…

In order to model an epidemic, different approaches can be adopted. Mainly, the deterministic approach and the stochastic one. Recently, a large amount of literature has been published using the two approaches. The aim of this paper is to…

Populations and Evolution · Quantitative Biology 2023-01-30 Mohamed Mehdaoui

Objectives: With accurate estimates of expected safety results, clinical trials could be better designed and monitored. We evaluated methods for predicting serious adverse event (SAE) results in clinical trials using information only from…

Computation and Language · Computer Science 2025-08-12 Qixuan Hu , Xumou Zhang , Jinman Kim , Florence Bourgeois , Adam G. Dunn

Objective: Machine learning algorithms are now widely used in predicting acute events for clinical applications. While most of such prediction applications are developed to predict the risk of a particular acute event at one hospital, few…

Immediately following a disaster event, such as an earthquake, estimates of the damage extent play a key role in informing the coordination of response and recovery efforts. We develop a novel impact estimation tool that leverages a…

Applications · Statistics 2025-01-15 Max Anderson Loake , Hamish Patten , David Steinsaltz

Purpose: Pulmonary embolism (PE) is a significant cause of mortality in the United States. The objective of this study is to implement deep learning (DL) models using Computed Tomography Pulmonary Angiography (CTPA), clinical data, and PE…

Rapidly advancing artificial intelligence (AI) systems introduce novel, uncertain, and potentially catastrophic risks. Managing these risks requires a mature risk-management infrastructure whose cornerstone is rigorous risk modeling. We…

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

In this paper a method is introduced, to visualize bifurcated stent grafts in CT-Data. The aim is to improve therapy planning for minimal invasive treatment of abdominal aortic aneurysms (AAA). Due to precise measurement of the abdominal…

Graphics · Computer Science 2016-02-09 Jan Egger , Stefan Großkopf , Bernd Freisleben

Aerodynamic optimization is ubiquitous in the design of most engineering systems interacting with fluids. A common approach is to optimize a performance function defined by a choice of an aerodynamic model, e.g., turbulence RANS model, and…

Optimization and Control · Mathematics 2021-05-04 Lluís Jofre , Alireza Doostan

We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling…

Logic in Computer Science · Computer Science 2011-11-10 Pietro Liò , Emanuela Merelli , Nicola Paoletti

Clinical decisions are often guided by clinical prediction models or diagnostic tests. Decision curve analysis (DCA) combines classical assessment of predictive performance with the consequences of using these strategies for clinical…

Methodology · Statistics 2023-08-07 Giuliano N. F. Cruz , Keegan Korthauer

How do we know if two systems - biological or artificial - process information in a similar way? Similarity measures such as linear regression, Centered Kernel Alignment (CKA), Normalized Bures Similarity (NBS), and angular Procrustes…

Neurons and Cognition · Quantitative Biology 2024-12-31 Nathan Cloos , Moufan Li , Markus Siegel , Scott L. Brincat , Earl K. Miller , Guangyu Robert Yang , Christopher J. Cueva

A commonly adopted approach to carry out detection tasks in medical imaging is to rely on an initial segmentation. However, this approach strongly depends on voxel-wise annotations which are repetitive and time-consuming to draw for medical…

BACKGROUND AND PURPOSE: Cerebral aneurysm is one of the most common cerebrovascular diseases, and SAH caused by its rupture has a very high mortality and disability rate. Existing automatic segmentation methods based on DLMs with TOF-MRA…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Meng Chen , Chen Geng , Dongdong Wang , Jiajun Zhang , Ruoyu Di , Fengmei Li , Zhiyong Zhou , Sirong Piao , Yuxin Li , Yaikang Dai

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and…

Patients resuscitated from cardiac arrest (CA) face a high risk of neurological disability and death, however pragmatic methods are lacking for accurate and reliable prognostication. The aim of this study was to build computational models…

Human error remains a dominant risk driver in safety-critical sectors such as nuclear power, aviation, and healthcare, where seemingly minor mistakes can cascade into catastrophic outcomes. Although decades of research have produced a rich…

Human-Computer Interaction · Computer Science 2025-07-02 Xingyu Xiao , Hongxu Zhu , Jingang Liang , Jiejuan Tong , Haitao Wang

In the complex realm of cognitive disorders, Alzheimer's disease (AD) and vascular dementia (VaD) are the two most prevalent dementia types, presenting entangled symptoms yet requiring distinct treatment approaches. The crux of effective…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Salma Hassan , Dawlat Akaila , Maryam Arjemandi , Vijay Papineni , Mohammad Yaqub
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