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Endovascular coil embolization is one of the primary treatment techniques for cerebral aneurysms. Although it is a well established and minimally invasive method, it bears the risk of sub-optimal coil placement which can lead to incomplete…

Computational Engineering, Finance, and Science · Computer Science 2024-02-06 Fabian Holzberger , Markus Muhr , Barbara Wohlmuth

Abdominal aortic aneurysms (AAAs) are progressive focal dilatations of the abdominal aorta. AAAs may rupture, with a survival rate of only 20\%. Current clinical guidelines recommend elective surgical repair when the maximum AAA diameter…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Dieuwertje Alblas , Patryk Rygiel , Julian Suk , Kaj O. Kappe , Marieke Hofman , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink

Purpose: To develop an open-source nnU-Net-based AI model for combined detection and segmentation of unruptured intracranial aneurysms (UICA) in 3D TOF-MRI, and compare models trained on datasets with aneurysm-like differential diagnoses.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Ashraya K. Indrakanti , Jakob Wasserthal , Martin Segeroth , Shan Yang , Victor Schulze-Zachau , Joshy Cyriac , Michael Bach , Marios Psychogios , Matthias A. Mutke

Abdominal aortic aneurysm (AAA) is a vascular disease in which a section of the aorta enlarges, weakening its walls and potentially rupturing the vessel. Abdominal ultrasound has been utilized for diagnostics, but due to its limited image…

Image and Video Processing · Electrical Eng. & Systems 2022-08-12 Yordanka Velikova , Walter Simson , Mehrdad Salehi , Mohammad Farid Azampour , Philipp Paprottka , Nassir Navab

Intracranial aneurysms (IAs), characterized by unpredictable growth and risk of rupture, are a major cause of stroke and can lead to life-threatening hemorrhages with high mortality and long-term disability. With aging populations, the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Marten J. Finck , Niklas C. Koser , Sarker M. Mahfuz , Tameem Jahangir , Jon E. Wilhelm , Daniel Behme , Naomi Larsen , Wojtek Palubicki , Sylvia Saalfeld , Sören Pirk

Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Patryk Rygiel , Julian Suk , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink

Clinical decisions for unruptured intracranial aneurysms depend on detecting growth on follow-up magnetic resonance angiography (MRA). Growth is typically judged from manual 2D diameters on few slices, which vary across clinicians and…

Intracranial aneurysms are a commonly occurring and life-threatening condition, affecting approximately 3.2% of the general population. Consequently, detecting these aneurysms plays a crucial role in their management. Lesion detection…

Computer Vision and Pattern Recognition · Computer Science 2023-05-24 Maysam Orouskhani , Negar Firoozeh , Shaojun Xia , Mahmud Mossa-Basha , Chengcheng Zhu

Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Erin Rainville , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Intracranial aneurysms are common nowadays and how to detect them intelligently is of great significance in digital health. While most existing deep learning research focused on medical images in a supervised way, we introduce an…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Di Shao , Xuequan Lu , Xiao Liu

In CT angiography, the accurate segmentation of abdominal aortic aneurysms (AAAs) is difficult due to large anatomical variability, low-contrast vessel boundaries, and the close proximity of organs whose intensities resemble vascular…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Osamah Sufyan , Martin Brückmann , Ralph Wickenhöfer , Babette Dellen , Uwe Jaekel

Brain aneurysm detection in Time-Of-Flight Magnetic Resonance Angiography (TOF-MRA) has undergone drastic improvements with the advent of Deep Learning (DL). However, performances of supervised DL models heavily rely on the quantity of…

Background: For the clinical adoption of stress-based rupture risk estimation in abdominal aortic aneurysms (AAAs), a fully automated pipeline, from clinical imaging to biomechanical stress computation, is essential. To this end, we…

Cerebral aneurysm rupture, leading to subarachnoid hemorrhage with a high mortality rate, disproportionately affects younger populations, resulting in a significant loss of productive life years. A significant proportion of these deaths is…

Computational Engineering, Finance, and Science · Computer Science 2025-07-17 Mostafa Jamshidian , Benjamin Zwick , Arosha S Dissanayake , Adam Wittek , Timothy J Phillips , Stephen Honeybul , Graeme J Hankey , Karol Miller

Purpose: To develop CADIA, a supervised deep learning model based on a region proposal network coupled with a false-positive reduction module for the detection and localization of intracranial aneurysms (IA) from computed tomography…

Image and Video Processing · Electrical Eng. & Systems 2021-12-16 Dufan Wu , Daniel Montes , Ziheng Duan , Yangsibo Huang , Javier M. Romero , Ramon Gilberto Gonzalez , Quanzheng Li

The development and progression of abdominal aortic aneurysms (AAA) are related to complex flow patterns and wall-shear-driven mechanobiological stimuli, yet the quantitative relationship between aneurysmal geometry and hemodynamics remains…

During intracranial aneurysm (IA) treatment with Diverters (FDs), the device/parent artery diameters ratio may influence the ability of the device to induce aneurysm healing response. Oversized FDs are safer to deploy but may not induce…

Enodvascular coils treat intracranial aneurysms (IAs) by causing them to occlude by thrombosis. Ideally, coiled IAs eventually occlude in the long-term. However, 20.8% are found incompletely occluded at treatment follow-up. Computer…

Endovascular treatment of cerebral aneurysms aims to achieve functional occlusion and isolation of the aneurysm sac from bloodflow. In clinical practice, treatment success is assessed primarily through digital subtraction angiography (DSA),…

Computational Engineering, Finance, and Science · Computer Science 2026-05-06 Fabian Holzberger , Struan Hume , Markus Muhr , Malebogo Ngoepe , Barbara Wohlmuth

Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Ashutosh Jadhav , Satyananda Kashyap , Hakan Bulu , Ronak Dholakia , Amon Y. Liu , Tanveer Syeda-Mahmood , William R. Patterson , Hussain Rangwala , Mehdi Moradi