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A major challenge in medical image analysis is the automated detection of biomarkers from neuroimaging data. Traditional approaches, often based on image registration, are limited in capturing the high variability of cortical organisation…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Dániel Unyi , Bálint Gyires-Tóth

Mapping the connectome of the human brain using structural or functional connectivity has become one of the most pervasive paradigms for neuroimaging analysis. Recently, Graph Neural Networks (GNNs) motivated from geometric deep learning…

Neurons and Cognition · Quantitative Biology 2022-11-30 Hejie Cui , Wei Dai , Yanqiao Zhu , Xuan Kan , Antonio Aodong Chen Gu , Joshua Lukemire , Liang Zhan , Lifang He , Ying Guo , Carl Yang

Neuronavigation is widely used in biomedical research and interventions to guide the precise placement of instruments around the head to support procedures such as transcranial magnetic stimulation. Traditional systems, however, rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Ziye Xie , Oded Schlesinger , Raj Kundu , Jessica Y. Choi , Pablo Iturralde , Dennis A. Turner , Stefan M. Goetz , Guillermo Sapiro , Angel V. Peterchev , J. Matias Di Martino

The neuronal networks in the mammals cortex are characterized by the coexistence of hierarchy, modularity, short and long range interactions, spatial correlations, and topographical connections. Particularly interesting, the latter type of…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa , Luis Diambra

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

The connectional brain template (CBT) captures the shared traits across all individuals of a given population of brain connectomes, thereby acting as a fingerprint. Estimating a CBT from a population where brain graphs are derived from…

Neurons and Cognition · Quantitative Biology 2022-09-28 Ece Cinar , Sinem Elif Haseki , Alaa Bessadok , Islem Rekik

Currently, connectomes (e.g., functional or structural brain graphs) can be estimated in humans at $\approx 1~mm^3$ scale using a combination of diffusion weighted magnetic resonance imaging, functional magnetic resonance imaging and…

Neuromechanics aims to understand the link between an animal's neural activity and its physical behaviors. Recent advances in experimental and machine learning techniques enable simultaneous recordings of neural and locomotion dynamics over…

Biological Physics · Physics 2026-05-06 Alexander E. Cohen , Jörn Dunkel

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

Recent progress in diffusion MRI and tractography algorithms as well as the launch of the Human Connectome Project (HCP) have provided brain research with an abundance of structural connectivity data. In this work, we describe and evaluate…

Neurons and Cognition · Quantitative Biology 2016-06-02 Kamal Shadi , Saideh Bakhshi , David A. Gutman , Helen S. Mayberg , Constantine Dovrolis

Understanding the mechanisms of neural communication in large-scale brain networks remains a major goal in neuroscience. We investigated whether navigation is a parsimonious routing model for connectomics. Navigating a network involves…

Neurons and Cognition · Quantitative Biology 2018-06-05 Caio Seguin , Martijn P. van den Heuvel , Andrew Zalesky

Brain interfaces are cyber-physical systems that aim to harvest information from the (physical) brain through sensing mechanisms, extract information about the underlying processes, and decide/actuate accordingly. Nonetheless, the brain…

Neurons and Cognition · Quantitative Biology 2018-03-29 Gaurav Gupta , Sergio Pequito , Paul Bogdan

High-resolution neural datasets enable foundation models for the next generation of brain-computer interfaces and neurological treatments. The community requires rigorous benchmarks to discriminate between competing modeling approaches, yet…

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

Neuroimaging studies, such as the Human Connectome Project (HCP), often collect multi-faceted and multi-block data to study the complex human brain. However, these data are often analyzed in a pairwise fashion, which can hinder our…

Neurons and Cognition · Quantitative Biology 2024-09-02 Andrew Ackerman , Zhengwu Zhang , Jan Hannig , Jack Prothero , J. S. Marron

A key element of the European Union's Human Brain Project (HBP) and other large-scale brain research projects is simulation of large-scale model networks of neurons. Here we argue why such simulations will likely be indispensable for…

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

Quantitative Methods · Quantitative Biology 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

Efficient brain simulation is a scientific grand challenge, a parallel/distributed coding challenge and a source of requirements and suggestions for future computing architectures. Indeed, the human brain includes about 10^15 synapses and…

We propose a new framework, called Hierarchical Multi-resolution Mesh Networks (HMMNs), which establishes a set of brain networks at multiple time resolutions of fMRI signal to represent the underlying cognitive process. The suggested…

Neural and Evolutionary Computing · Computer Science 2017-01-13 Itir Onal Ertugrul , Mete Ozay , Fatos Tunay Yarman Vural

The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett
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