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In this work, we develop a theory of light transmission through a Zero-Mode Waveguide (ZMW) containing a single atom. It is shown that the presence of a single atom inside the ZMW can lead to either a significant enhancement or suppression…

Quantum Physics · Physics 2025-09-01 Vasily Klimov

We fabricated hybrid metal-dielectric nanoantennas and measured their optical response at three different wavelengths. The nanostructure is fabricated on a bilayer film formed by the sequential deposition of silicon and gold on a…

Single molecule detection provides detailed information about molecular structures and functions, but it generally requires the presence of a fluorescent marker which can interfere with the activity of the target molecule or complicate the…

Zero-mode waveguide (ZMW) nanoapertures are widely used to monitor single molecules beyond the range accessible to normal microscopes. However, several aspects of the ZMW influence on the photophysics of fluorophores remain inadequately…

Optics · Physics 2022-05-04 Satyajit Patra , Jean-Benoît Claude , Jérôme Wenger

This paper presents the work achieved for the manufacturing and characterization of first single-mode waveguides to be used as modal filters for nulling interferometry in the mid-infrared range [4-20 um]. As very high dynamic range is…

Astrophysics · Physics 2009-11-11 L. Labadie , P. Labeye , P. Kern , I. Schanen , B. Arezki , J. -E. Broquin

Zero-mode waveguides (ZMWs) are confining light into attoliter volumes, enabling single molecule fluorescence experiments at physiological micromolar concentrations. Among the fluorescence spectroscopy techniques that can be enhanced by…

Metals are canonical plasmonic media at infrared and optical wavelengths, allowing one to guide and manipulate light at the nano-scale. A special form of optical waveguiding is afforded by highly anisotropic crystals revealing the opposite…

Single-molecule approaches to biology offer a powerful new vision to elucidate the mechanisms that underpin the functioning of living cells. However, conventional optical single molecule spectroscopy techniques such as F\"orster…

Single nanoparticle tracking using optical microscopy is a powerful technique with many applications in biology, chemistry and material sciences. Despite significant advances, localising objects with nanometric position accuracy in a…

The selective optical detection of individual metallic nanoparticles (NPs) with high spatial and temporal resolution is a challenging endeavour, yet is key to the understanding of their optical response and their exploitation in…

Mesoscale and Nanoscale Physics · Physics 2012-06-05 Francesco Masia , Wolfgang Langbein , Paola Borri

Single molecule F\"orster resonance energy transfer (smFRET) is widely used to monitor conformations and interactions dynamics at the molecular level. However, conventional smFRET measurements are ineffective at donor-acceptor distances…

The quasi-bound electromagnetic modes for the arrays of nanoholes perforated in thin gold film are analyzed both numerically by the rigorous coupled wave analysis (RCWA) method and semi-analytically by the coupled mode method. It is shown…

Optics · Physics 2015-06-10 Munehiro Nishida , Noriyuki Hatakenaka , Yutaka Kadoya

This paper reports the characterization of hollow metallic waveguides (HMW) to be used as single-mode wavefront filters for nulling interferometry in the 6-20 microns range. The measurements presented here were performed using both…

Nanophotonics, the study of light-matter interaction at scales smaller than the wavelength of radiation, has widespread applications in plasmonic waveguiding, topological photonic crystals, super-lensing, solar absorbers, and infrared…

Optics · Physics 2024-09-23 Sathwik Bharadwaj , Zubin Jacob

Zero mode waveguide (ZMW) nanoapertures efficiently confine the light down to the nanometer scale and overcome the diffraction limit in single molecule fluorescence analysis. However, unwanted adhesion of the fluorescent molecules on the…

Chemical Physics · Physics 2020-01-15 Satyajit Patra , Mikhail Baibakov , Jean-Benoît Claude , Jérôme Wenger

Over the last decade, single-molecule optical microscopy has become the gold-standard approach to decipher complex molecular processes in cellular environments. [1-3] Single-molecule fluorescence microscopy has several advantages such as…

Biological Physics · Physics 2017-11-15 Edakkattuparambil Sidharth Shibu , Nadezda Varkentina , Laurent Cognet , Brahim Lounis

Superconducting Nanowire Single-Photon Detectors (SNSPDs) are key building blocks for photonic quantum technologies due to their ability to detect single photons with ultra-high efficiency, low dark counts and fast temporal resolution.…

Detection and characterization of individual nano-scale particles, virions, and pathogens are of paramount importance to human health, homeland security, diagnostic and environmental monitoring[1]. There is a strong demand for…

Optics · Physics 2011-07-06 Lina He , Sahin Kaya Ozdemir , Jiangang Zhu , Woosung Kim , Lan Yang

Current optical detection schemes for single molecules require light absorption, either to produce fluorescence or direct absorption signals. This severely limits the range of molecules that can be detected, because most molecules are…

Chemical Physics · Physics 2012-07-06 Peter Zijlstra , Pedro M. R. Paulo , Michel Orrit

Solid-state nanopores are emerging platforms for single-molecule protein sequencing due to their tolerance to hash physiology environment and compatibility with different electrical and optical detection methods. However, they suffer from…

Applied Physics · Physics 2024-01-05 Yingqi Zhao , Aliaksandr Hubarevich , Jian-An Huang , Francesco De Angelis
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