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The application of natural language processing (NLP) to cancer pathology reports has been focused on detecting cancer cases, largely ignoring precancerous cases. Improving the characterization of precancerous adenomas assists in developing…

Machine Learning · Computer Science 2022-12-13 Yizhen Zhong , Jiajie Xiao , Thomas Vetterli , Mahan Matin , Ellen Loo , Jimmy Lin , Richard Bourgon , Ofer Shapira

Electronic health records (EHR) contain large volumes of unstructured text, requiring the application of Information Extraction (IE) technologies to enable clinical analysis. We present the open-source Medical Concept Annotation Toolkit…

Ontologies are essential for structuring domain knowledge, improving accessibility, sharing, and reuse. However, traditional ontology construction relies on manual annotation and conventional natural language processing (NLP) techniques,…

Artificial Intelligence · Computer Science 2026-02-03 Xuan Liu , Ziyu Li , Mu He , Ziyang Ma , Xiaoxu Wu , Gizem Yilmaz , Yiyuan Xia , Bingbing Li , He Tan , Jerry Ying Hsi Fuh , Wen Feng Lu , Anders E. W. Jarfors , Per Jansson

Biomedical literature is a rapidly expanding field of science and technology. Classification of biomedical texts is an essential part of biomedicine research, especially in the field of biology. This work proposes the fine-tuned DistilBERT,…

Computation and Language · Computer Science 2024-04-23 Ziqing Guo

An automated knowledge modeling algorithm for Cancer Clinical Practice Guidelines (CPGs) extracts the knowledge contained in the CPG documents and transforms it into a programmatically interactable, easy-to-update structured model with…

Computation and Language · Computer Science 2024-08-01 Pralaypati Ta , Bhumika Gupta , Arihant Jain , Sneha Sree C , Keerthi Ram , Mohanasankar Sivaprakasam

Crucial information about the practice of healthcare is recorded only in free-form text, which creates an enormous opportunity for high-impact NLP. However, annotated healthcare datasets tend to be small and expensive to obtain, which…

Computation and Language · Computer Science 2019-04-09 Yifeng Tao , Bruno Godefroy , Guillaume Genthial , Christopher Potts

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Medical information extraction consists of a group of natural language processing (NLP) tasks, which collaboratively convert clinical text to pre-defined structured formats. Current state-of-the-art (SOTA) NLP models are highly integrated…

Computation and Language · Computer Science 2022-03-09 Enwei Zhu , Qilin Sheng , Huanwan Yang , Jinpeng Li

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

This paper studies the automated categorization and extraction of scientific concepts from titles of scientific articles, in order to gain a deeper understanding of their key contributions and facilitate the construction of a generic…

Information Retrieval · Computer Science 2017-11-10 Adit Krishnan , Aravind Sankar , Shi Zhi , Jiawei Han

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Current methods for Black-Box NLP interpretability, like LIME or SHAP, are based on altering the text to interpret by removing words and modeling the Black-Box response. In this paper, we outline limitations of this approach when using…

Computation and Language · Computer Science 2022-08-09 Yves Rychener , Xavier Renard , Djamé Seddah , Pascal Frossard , Marcin Detyniecki

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Pathology reports serve as the definitive record for breast cancer staging, yet their unstructured format impedes large-scale data curation. While Large Language Models (LLMs) offer semantic reasoning, their deployment is often limited by…

Machine Learning · Computer Science 2026-04-16 Jiahao Shao , Anam Nawaz Khan , Christopher Brett , Tom Berg , Xueping Li , Bing Yao

Clinical notes contain unstructured representations of patient histories, including the relationships between medical problems and prescription drugs. To investigate the relationship between cancer drugs and their associated symptom burden,…

Computation and Language · Computer Science 2024-09-09 Yujuan Fu , Giridhar Kaushik Ramachandran , Ahmad Halwani , Bridget T. McInnes , Fei Xia , Kevin Lybarger , Meliha Yetisgen , Özlem Uzuner

The updated recommendations on diagnostic procedures and treatment pathways for a medical condition are documented as graphical flows in Clinical Practice Guidelines (CPGs). For effective use of the CPGs in helping medical professionals in…

Computation and Language · Computer Science 2025-01-27 Bhumika Gupta , Pralaypati Ta , Keerthi Ram , Mohanasankar Sivaprakasam

Natural language processing (NLP) practitioners are leveraging large language models (LLM) to create structured datasets from semi-structured and unstructured data sources such as patents, papers, and theses, without having domain-specific…

Computation and Language · Computer Science 2024-03-26 Jesse Atuhurra , Seiveright Cargill Dujohn , Hidetaka Kamigaito , Hiroyuki Shindo , Taro Watanabe

This work proposes a novel approach to text categorization -- for unknown categories -- in the context of scientific literature, using Natural Language Processing techniques. The study leverages the power of pre-trained language models,…

Computation and Language · Computer Science 2023-09-14 Rosanna Turrisi

Population-based cancer registries depend on pathology reports as their primary diagnostic source, yet manual abstraction is resource-intensive and contributes to delays in cancer data. While transformer-based NLP systems have improved…

Computation and Language · Computer Science 2026-01-05 Jonathan Simkin , Lovedeep Gondara , Zeeshan Rizvi , Gregory Doyle , Jeff Dowden , Dan Bond , Desmond Martin , Raymond Ng
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