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The Precision Medicine Initiative states that treatments for a patient should take into account not only the patient's disease, but his/her specific genetic variation as well. The vast biomedical literature holds the potential for…

Information Retrieval · Computer Science 2019-04-22 Jiaming Qu , Yue Wang

Objective: The generalizability of clinical large language models is usually ignored during the model development process. This study evaluated the generalizability of BERT-based clinical NLP models across different clinical settings…

Computation and Language · Computer Science 2023-03-16 Sicheng Zhou , Nan Wang , Liwei Wang , Ju Sun , Anne Blaes , Hongfang Liu , Rui Zhang

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

While natural language processing (NLP) of unstructured clinical narratives holds the potential for patient care and clinical research, portability of NLP approaches across multiple sites remains a major challenge. This study investigated…

According to the World Health Organization (WHO), cancer is the second leading cause of death globally. Scientific research on different types of cancers grows at an ever-increasing rate, publishing large volumes of research articles every…

Computation and Language · Computer Science 2023-06-27 G. Jeyakodi , Arkadeep Pal , Debapratim Gupta , K. Sarukeswari , V. Amouda

A data-centric approach with Natural Language Processing (NLP) to predict personality types based on the MBTI (an introspective self-assessment questionnaire that indicates different psychological preferences about how people perceive the…

Computation and Language · Computer Science 2021-05-26 Carlos Basto

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

We present a demonstration of the utility of NLP for aiding research into energetic materials and associated systems. The NLP method enables machine understanding of textual data, offering an automated route to knowledge discovery and…

Computation and Language · Computer Science 2024-02-13 Francis G. VanGessel , Efrem Perry , Salil Mohan , Oliver M. Barham , Mark Cavolowsky

More than 200 generic drugs approved by the U.S. Food and Drug Administration for non-cancer indications have shown promise for treating cancer. Due to their long history of safe patient use, low cost, and widespread availability,…

The integration of Large Language Models (LLMs) into biomedical research offers new opportunities for domainspecific reasoning and knowledge representation. However, their performance depends heavily on the semantic quality of training…

Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

Using different sources of information to support automated extracting of relations between biomedical concepts contributes to the development of our understanding of biological systems. The primary comprehensive source of these relations…

Computation and Language · Computer Science 2020-09-21 Diana Sousa , Andre Lamurias , Francisco M. Couto

This work presents our participation in the EvalLLM 2025 challenge on biomedical Named Entity Recognition (NER) and health event extraction in French (few-shot setting). For NER, we propose three approaches combining large language models…

Objective: We aim to develop an open-source natural language processing (NLP) package, SODA (i.e., SOcial DeterminAnts), with pre-trained transformer models to extract social determinants of health (SDoH) for cancer patients, examine the…

The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and…

The objective of this study is to develop natural language processing (NLP) models that can analyze patients' drug reviews and accurately classify their satisfaction levels as positive, neutral, or negative. Such models would reduce the…

Computation and Language · Computer Science 2023-08-09 Yue Ling

Driven by the visions of Data Science, recent years have seen a paradigm shift in Natural Language Processing (NLP). NLP has set the milestone in text processing and proved to be the preferred choice for researchers in the healthcare…

Computers and Society · Computer Science 2020-07-20 Ganga Prasad Basyal , Bhaskar P. Rimal , David Zeng

Objective: The majority of detailed patient information in real-world data (RWD) is only consistently available in free-text clinical documents. Manual curation is expensive and time-consuming. Developing natural language processing (NLP)…

Clinical notes are an essential component of a health record. This paper evaluates how natural language processing (NLP) can be used to identify the risk of acute care use (ACU) in oncology patients, once chemotherapy starts. Risk…

Computation and Language · Computer Science 2023-06-28 Claudio Fanconi , Marieke van Buchem , Tina Hernandez-Boussard

In the past year, there has been a growing trend in applying Large Language Models (LLMs) to the field of medicine, particularly with the advent of advanced language models such as ChatGPT developed by OpenAI. However, there is limited…

Computation and Language · Computer Science 2024-02-27 Fujian Jia , Xin Liu , Lixi Deng , Jiwen Gu , Chunchao Pu , Tunan Bai , Mengjiang Huang , Yuanzhi Lu , Kang Liu