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The clinical and economic burden of cardiovascular diseases (CVDs) poses a global challenge. Growing evidence suggests an early assessment of arterial stiffness can provide insights into the pathogenesis of CVDs. However, it remains…

Medical Physics · Physics 2020-12-07 Guo-Yang Li , Yuxuan Jiang , Yang Zheng , Weiqiang Xu , Zhaoyi Zhang , Yanping Cao

Estimating an individual treatment effect (ITE) is essential to personalized decision making. However, existing methods for estimating the ITE often rely on unconfoundedness, an assumption that is fundamentally untestable with observed…

Methodology · Statistics 2022-07-13 Mingzhang Yin , Claudia Shi , Yixin Wang , David M. Blei

Observations of ion-scale (k_y*rho_i <= 1) density turbulence of relative amplitude dn_e/n_e <= 0.2% are available on the Mega Amp Spherical Tokamak (MAST) using a 2D (8 radial x 4 poloidal channel) imaging Beam Emission Spectroscopy (BES)…

Plasma Physics · Physics 2014-01-08 A R Field , D Dunai , Y-c Ghim , P Hill , B McMillan , C M Roach , S Saarelma , A A Schekochihin , S Zoletnik , the MAST team

Despite the widespread diffusion of nonlinear methods for heart rate variability (HRV) analysis, the presence and the extent to which nonlinear dynamics contribute to short-term HRV is still controversial. This work aims at testing the…

Arterial pulse waves contain clinically useful information: their intensity varies with cardiac performance, their speed (pulse wave velocity; PWV) depends on arterial stiffness and their reflection is affected by conduit artery tone. Here…

Medical Physics · Physics 2022-05-31 Ethan M Rowland , Kai Riemer , Kevin Lichtenstein , Mengxing Tang , Peter Weinberg

An experimental testbed has been constructed to assess the capabilities of Light-Wave Sensing, a promising new vitals monitoring approach. A Light-Wave Sensing apparatus utilizes infrared radiation to contactlessly monitor the subtle…

Medical Physics · Physics 2023-11-08 Brenden Martin , Md Zobaer Islam , Carly Gotcher , Tyler Martinez , Sabit Ekin , John F. O'Hara

Isothermal rebreathing has been proposed as an experimental technique for estimating the alveolar levels of hydrophilic volatile organic compounds (VOCs) in exhaled breath. Using the prototypic test compound acetone we demonstrate that the…

Quantitative Methods · Quantitative Biology 2012-12-11 Julian King , Karl Unterkofler , Gerald Teschl , Susanne Teschl , Pawel Mochalski , Helin Koc , Hartmann Hinterhuber , Anton Amann

We present the Empirical Dust Attenuation (EDA) framework -- a flexible prescription for assigning realistic dust attenuation to simulated galaxies based on their physical properties. We use the EDA to forward model synthetic observations…

Using shear wave elastography, we measure the changes in the wave speed with the stress produced by a striated muscle during isometric voluntary contraction. To isolate the behaviour of an individual muscle from complementary or…

Diagnosing epilepsy is challenging when routine EEGs lack interictal epileptiform discharges (IEDs). Intermittent photic stimulation (IPS) and hyperventilation (HV) can increase diagnostic yield, but their interpretation is subjective. We…

Signal Processing · Electrical Eng. & Systems 2026-05-25 Giacomo Zanardini , Ryan Moesman , Paul van der Kleij , Robert van den Berg , Justin Dauwels

A study of turbulent impurity transport by means of quasilinear and nonlinear gyrokinetic simulations is presented for Wendelstein 7-X (W7-X). The calculations have been carried out with the recently developed gyrokinetic code stella.…

Multiple-breath-washout (MBW) measurements are regarded as a sensitive technique which can reflect the ventilation inhomogeneity of respiratory airways. Typically nitrogen is used as the tracer gas and is washed out by pure oxygen in…

Medical Physics · Physics 2011-11-28 Jau-Yi Wang , Matt Suddards , John Owers-Bradley , Chris Mellor

We introduce iTRIALSPACE, a programmable evaluation framework for controlled assessment of lung CT models. Standard benchmarks are static retrospective collections that entangle lesion size, lobe prevalence, anatomy, and acquisition…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Fakrul Islam Tushar , Umme Hafsa Momy , Joseph Y. Lo , Geoffrey D. Rubin

Non-invasive at-home monitoring of lung and lung airways health enables the early detection and tracking of respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD). Various proposed approaches estimate the…

Signal Processing · Electrical Eng. & Systems 2021-10-12 Maria Nyamukuru , Kofi Odame

In this paper, we provide non-parametric statistical tools to test stationarity of microstructure noise in general hidden Ito semimartingales, and discuss how to measure liquidity risk using high frequency financial data. In particular, we…

Statistical Finance · Quantitative Finance 2019-11-07 Richard Y. Chen , Per A. Mykland

We review recent relativistic hydrodynamic simulations of jets, and their interpretation in terms of the results from linear stability analysis. These studies show that, interpreted naively, the distribution of synchrotron intensity will in…

Astrophysics · Physics 2007-05-23 Philip A. Hughes

We investigate the efficacy of surgical versus non-surgical management for two gastrointestinal conditions, colitis and diverticulitis, using observational data. We deploy an instrumental variable design with surgeons' tendencies to operate…

Applications · Statistics 2020-12-11 Colin B. Fogarty , Kwonsang Lee , Rachel R. Kelz , Luke J. Keele

The immersed boundary (IB) method is a mathematical framework for fluid-structure interaction problems (FSI) that was originally developed to simulate flows around heart valves. Direct comparison of FSI simulations around heart valves…

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

Systems and Control · Electrical Eng. & Systems 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

Sequential trial emulation (STE) is an approach to estimating causal treatment effects by emulating a sequence of target trials from observational data. In STE, inverse probability weighting is commonly utilised to address time-varying…

Methodology · Statistics 2025-07-10 Juliette M. Limozin , Shaun R. Seaman , Li Su