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Heat generated from plasmonic nanoparticles can be utilized in plasmonic photothermal therapy. A combination of near-infrared laser and metallic nanoparticles are compelling for the treatment of brain cancer, due to their efficient…

Brain tissue is a heterogeneous material, constituted by a soft matrix filled with cerebrospinal fluid. The interactions between, and the complexity of each of these components are responsible for the non-linear rate-dependent behaviour…

Quantitative Methods · Quantitative Biology 2021-02-23 Michele Terzano , Andrea Spagnoli , Daniele Dini , Antonio Elia Forte

After the discovery of laser therapy it was realized it has useful application of wound healing and reduce pain, but due to the poor understanding of the mechanism and dose response this technique remained to be controversial for…

Medical Physics · Physics 2016-06-16 Muhammad Zeeshan Khalid

Currently, free flaps and pedicled flaps are assessed for reperfusion in post-operative care using colour, capillary refill, temperature, texture and Doppler signal (if available). While these techniques are effective, they are prone to…

Medical Physics · Physics 2022-04-18 Mark Main , Richard JJ Pilkington , Graham M Gibson , Akhil Kallepalli

The objective of this work is to investigate the coupling of fluid dynamics, heat transfer and mass transfer during the impact and evaporation of droplets on a heated solid substrate. A laser-based thermoreflectance method is used to…

Fluid Dynamics · Physics 2010-10-14 Rajneesh Bhardwaj , Jon P. Longtin , Daniel Attinger

The different active roles of neurons and astrocytes during neuronal activation are associated with the metabolic processes necessary to supply the energy needed for their respective tasks at rest and during neuronal activation. Metabolism,…

Tissues and Organs · Quantitative Biology 2022-11-07 Gideon Idumah , Erkki Somersalo , Daniela Calvetti

Transcranial photobiomodulation is an optical method for non-invasive brain stimulation. The method projects red and near-infrared light through the scalp within 600-1100 nm and low energy within the 1-20 J/cm2 range. Recent studies have…

Numerical Analysis · Mathematics 2022-12-12 Faezeh Ibrahimi , Mehdi Delrobaei

We are investigating the effective heat transfer in complex systems involving porous media and surrounding fluid layers in the context of mathematical homogenization. We differentiate between two fundamentally different cases: Case (a),…

Analysis of PDEs · Mathematics 2024-05-01 Michael Eden , Tom Freudenberg

This paper presents a computational model, based on the Finite Element Method (FEM), that simulates the thermal response of laser-irradiated tissue. This model addresses a gap in the current ecosystem of surgical robot simulators, which…

Heat transfer in the human eyeball, a complex organ, is significantly influenced by various pathophysiological and external parameters. Particularly, heat transfer critically affects fluid behavior within the eye and ocular drug delivery…

Analysis of PDEs · Mathematics 2024-10-14 Thomas Saigre , Christophe Prud'Homme , Marcela Szopos

A bio-heat transfer model for biological tissues in a micro-scale and periodical settings is investigated . It is assumed that the model is a two-component system consisting of solid particles representing tissue cells and interconnected…

Analysis of PDEs · Mathematics 2014-10-28 Abdelhamid Ainouz

Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…

In this paper, a three-dimensional finite element method is developed to simulate the heat distribution in the human eye with different types of tumors to understand the effect of tumors on heat distribution in the human eye. The human eye…

Tissues and Organs · Quantitative Biology 2022-07-20 Aboozar Moradi , Mohammad Reza Yousefi

Recent Brain-Machine Interfaces have shifted towards miniature devices that are constructed from nanoscale components. While these devices can be implanted into the brain, their functionalities can be limited, and will require communication…

Emerging Technologies · Computer Science 2019-11-04 Stefanus Wirdatmadja , Josep Miquel Jornet , Yevgeni Koucheryavy , Sasitharan Balasubramaniam

This paper presents a comprehensive computer simulation of thermal processes in multilayered biological tissues for the analysis of luminance temperature distributions recorded by microwave radiometry. A mathematical model combining the…

Biological Physics · Physics 2025-10-21 Maxim V. Polyakov , Illarion E. Popov

The Blood-Brain Barrier is the gatekeeper of the CNS. It effectively shields the brain from blood-borne harm but simultaneously represents a significant challenge for treating neurological diseases. Altering its permeability enables…

A comprehensive theory is proposed to describe the propagation and absorption of ultra-intense, short laser pulse through the under-dense plasma. The kinetic aspects of plasma are fully incorporated using extensive particle-in-cell (PIC)…

Plasma Physics · Physics 2015-12-01 Jam Yazdanpanah , Elnaz Yazdani , Amir Chakhmachi , Elnaz Khalilzadeh

In many laboratories, conventional bright-field transmission microscopes are available to study the structure and organization principles of fibrous tissue samples, but they usually provide only 2D information. To access the third…

Mathematical modelling of ionic electrodiffusion and water movement is emerging as a powerful avenue of investigation to provide new physiological insight into brain homeostasis. However, in order to provide solid answers and resolve…

Numerical Analysis · Mathematics 2022-01-24 Ada J. Ellingsrud , Nicolas Boullé , Patrick E. Farrell , Marie E. Rognes

Excitable tissue is fundamental to brain function, yet its study is complicated by extreme morphological complexity and the physiological processes governing its dynamics. Consequently, detailed computational modeling of this tissue…

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