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Cancer treatments require personalized approaches based on a patient's clinical condition, medical history, and evidence-based guidelines. The National Comprehensive Cancer Network (NCCN) provides frequently updated, complex guidelines…

Information Retrieval · Computer Science 2025-02-25 Abdul M. Mohammed , Iqtidar Mansoor , Sarah Blythe , Dennis Trujillo

Proton pencil beam scanning (PBS) treatment planning for head & neck (H&N) cancers involves numerous conflicting objectives, requiring iterative objective parameter adjustments to balance multiple clinical goals. We propose a…

Artificial Intelligence · Computer Science 2025-09-16 Qingqing Wang , Liqiang Xiao , Chang Chang

Accurate and realistic simulation of high-dimensional medical images has become an important research area relevant to many AI-enabled healthcare applications. However, current state-of-the-art approaches lack the ability to produce…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Daniele Ravi , Stefano B. Blumberg , Silvia Ingala , Frederik Barkhof , Daniel C. Alexander , Neil P. Oxtoby

Neural network pruning remains essential for deploying deep learning models on resource-constrained devices, yet existing approaches primarily target parameter reduction without directly controlling computational cost. This yields…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Shahrzad Esmat , Mahdi Banisharif , Ali Jannesari

Foundation models face growing compute and memory bottlenecks, hindering deployment on resource-limited platforms. While compression techniques such as pruning and quantization are widely used, most rely on uniform heuristics that ignore…

Machine Learning · Computer Science 2025-09-09 Sadegh Jafari , Aishwarya Sarkar , Mohiuddin Bilwal , Ali Jannesari

Recently, interest in MR-only treatment planning using synthetic CTs (synCTs) has grown rapidly in radiation therapy. However, developing class solutions for medical images that contain atypical anatomy remains a major limitation. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Hajar Emami , Ming Dong , Carri K. Glide-Hurst

Objective: This study aims to uncover the opaque decision-making process of an artificial intelligence (AI) agent for automatic treatment planning. Approach: We examined a previously developed AI agent based on the Actor-Critic with…

Medical Physics · Physics 2025-08-21 Md Mainul Abrar , Xun Jia , Yujie Chi

Deep neural networks (DNNs) are vulnerable to adversarial examples, which are crafted by adding imperceptible perturbations to inputs. Recently different attacks and strategies have been proposed, but how to generate adversarial examples…

Machine Learning · Computer Science 2021-01-13 Tao Bai , Jun Zhao , Jinlin Zhu , Shoudong Han , Jiefeng Chen , Bo Li , Alex Kot

Fontan palliation for univentricular congenital heart disease progresses to hemodynamic failure with complex flow patterns poorly characterized by conventional 2D imaging. Current assessment relies on fluoroscopic angiography, providing…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Prahlad G Menon

Pancreatic ductal adenocarcinoma (PDAC) presents a critical global health challenge, and early detection is crucial for improving the 5-year survival rate. Recent medical imaging and computational algorithm advances offer potential…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Yu Shi , Hannah Tang , Michael Baine , Michael A. Hollingsworth , Huijing Du , Dandan Zheng , Chi Zhang , Hongfeng Yu

Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Ruiwen Xing , Thomas Humphries , Dong Si

Translational brain research using Magnetic Resonance Imaging (MRI) is becoming increasingly popular as animal models are an essential part of scientific studies and more ultra-high-field scanners are becoming available. Some disadvantages…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 André Ferreira , Ricardo Magalhães , Sébastien Mériaux , Victor Alves

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

The synthesis of computed tomography (CT) from magnetic resonance imaging (MRI) and cone-beam CT (CBCT) plays a critical role in clinical treatment planning by enabling accurate anatomical representation in adaptive radiotherapy. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Siyuan Mei , Yan Xia , Fuxin Fan , Andreas Maier

Purpose: 4D MRI with high spatiotemporal resolution is desired for image-guided liver radiotherapy. Acquiring densely sampling k-space data is time-consuming. Accelerated acquisition with sparse samples is desirable but often causes…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Di Xu , Xin Miao , Hengjie Liu , Jessica E. Scholey , Wensha Yang , Mary Feng , Michael Ohliger , Hui Lin , Yi Lao , Yang Yang , Ke Sheng

It is well known that the inverse design of terahertz (THz) multi-resonant graphene metasurfaces by using traditional deep neural networks (DNNs) has limited generalization ability. In this paper, we propose improved Transformer and…

Optics · Physics 2023-07-25 Yangpeng Huang , Naixing Feng , Yijun Cai

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Medical Physics · Physics 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

Objective: To assess the performance of a probabilistic deep learning based algorithm for predicting inter-fraction anatomical changes in head and neck patients. Approach: A probabilistic daily anatomy model for head and neck patients…

Medical Physics · Physics 2024-11-12 Tiberiu Burlacu , Mischa Hoogeman , Danny Lathouwers , Zoltán Perkó

Early detection of intrapartum risks enables timely interventions to prevent or mitigate adverse labor outcomes such as cerebral palsy. However, accurate automated systems to support clinical decision-making during delivery are currently…

Purpose: To develop biophysics-based method for estimating perfusion Q from arterial spin labeling (ASL) images using deep learning. Methods: A 3D U-Net (QTMnet) was trained to estimate perfusion from 4D tracer propagation images. The…

Quantitative Methods · Quantitative Biology 2023-11-20 Renjiu Hu , Qihao Zhang , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang