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The success of deep learning has set new benchmarks for many medical image analysis tasks. However, deep models often fail to generalize in the presence of distribution shifts between training (source) data and test (target) data. One…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Dwarikanath Mahapatra

Bridging the 'reality gap' that separates simulated robotics from experiments on hardware could accelerate robotic research through improved data availability. This paper explores domain randomization, a simple technique for training models…

Robotics · Computer Science 2017-03-22 Josh Tobin , Rachel Fong , Alex Ray , Jonas Schneider , Wojciech Zaremba , Pieter Abbeel

For medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ziqi Zhou , Lei Qi , Xin Yang , Dong Ni , Yinghuan Shi

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

Despite the successes of deep neural networks on many challenging vision tasks, they often fail to generalize to new test domains that are not distributed identically to the training data. The domain adaptation becomes more challenging for…

Computer Vision and Pattern Recognition · Computer Science 2021-03-08 Devavrat Tomar , Manana Lortkipanidze , Guillaume Vray , Behzad Bozorgtabar , Jean-Philippe Thiran

Domain generalizable model is attracting increasing attention in medical image analysis since data is commonly acquired from different institutes with various imaging protocols and scanners. To tackle this challenging domain generalization…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Ran Gu , Jingyang Zhang , Rui Huang , Wenhui Lei , Guotai Wang , Shaoting Zhang

This paper investigates discrepancies in how neural networks learn from different imaging domains, which are commonly overlooked when adopting computer vision techniques from the domain of natural images to other specialized domains such as…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Nicholas Konz , Maciej A. Mazurowski

Automatic segmentation of magnetic resonance (MR) images is crucial for morphological evaluation of the pediatric musculoskeletal system in clinical practice. However, the accuracy and generalization performance of individual segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Arnaud Boutillon , Pierre-Henri Conze , Christelle Pons , Valérie Burdin , Bhushan Borotikar

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Cross-modal MRI segmentation is of great value for computer-aided medical diagnosis, enabling flexible data acquisition and model generalization. However, most existing methods have difficulty in handling local variations in domain shift…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Bingnan Li , Zhitong Gao , Xuming He

Medical image analysis (MedIA) has become an essential tool in medicine and healthcare, aiding in disease diagnosis, prognosis, and treatment planning, and recent successes in deep learning (DL) have made significant contributions to its…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Jee Seok Yoon , Kwanseok Oh , Yooseung Shin , Maciej A. Mazurowski , Heung-Il Suk

Domain generalization (DG) strives to address distribution shifts across diverse environments to enhance model's generalizability. Current DG approaches are confined to acquiring robust representations with continuous features, specifically…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Shaocong Long , Qianyu Zhou , Xikun Jiang , Chenhao Ying , Lizhuang Ma , Yuan Luo

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

Magnetic Resonance Imaging (MRI) is widely used in routine clinical diagnosis and treatment. However, variations in MRI acquisition protocols result in different appearances of normal and diseased tissue in the images. Convolutional neural…

Model calibration measures the agreement between the predicted probability estimates and the true correctness likelihood. Proper model calibration is vital for high-risk applications. Unfortunately, modern deep neural networks are poorly…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Skylar E. Stolte , Kyle Volle , Aprinda Indahlastari , Alejandro Albizu , Adam J. Woods , Kevin Brink , Matthew Hale , Ruogu Fang

Deep learning-based methods deliver state-of-the-art performance for solving inverse problems that arise in computational imaging. These methods can be broadly divided into two groups: (1) learn a network to map measurements to the signal…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Nebiyou Yismaw , Ulugbek S. Kamilov , M. Salman Asif

The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Serban Stan , Mohammad Rostami

Deep neural networks have achieved impressive performance in a wide variety of medical imaging tasks. However, these models often fail on data not used during training, such as data originating from a different medical centre. How to…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Joona Pohjonen , Carolin Stürenberg , Atte Föhr , Reija Randen-Brady , Lassi Luomala , Jouni Lohi , Esa Pitkänen , Antti Rannikko , Tuomas Mirtti

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge