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Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

Recent works have shown that quantum computers can polynomially speed up certain SAT-solving algorithms even when the number of available qubits is significantly smaller than the number of variables. Here we generalise this approach. We…

Quantum Physics · Physics 2020-02-19 Yimin Ge , Vedran Dunjko

With the advances in customized hardware for quantum annealing and digital/CMOS Annealing, Quadratic Unconstrained Binary Optimization (QUBO) models have received growing attention in the optimization literature. Motivated by an existing…

Quantum Physics · Physics 2024-04-05 Oksana Pichugina , Yingcong Tan , Christopher Beck

Ising Machines are emerging hardware architectures that efficiently solve NP-Hard combinatorial optimization problems. Generally, combinatorial problems are transformed into quadratic unconstrained binary optimization (QUBO) form, but this…

Hardware Architecture · Computer Science 2025-09-12 Chirag Garg , Sayeef Salahuddin

We present a quantum-inspired tensor network algorithm for solving tridiagonal Quadratic Unconstrained Binary Optimization (QUBO) problems and quadratic unconstrained discrete optimization (QUDO) problems. We also solve the more general…

Multi-Agent Path Finding (MAPF) remains a fundamental challenge in robotics, where classical centralized approaches exhibit exponential growth in joint-state complexity as the number of agents increases. This paper investigates Quadratic…

Robotics · Computer Science 2026-02-17 Javier González Villasmil

We introduce parity quantum optimization with the aim of solving optimization problems consisting of arbitrary $k$-body interactions and side conditions using planar quantum chip architectures. The method introduces a decomposition of the…

Quadratic unconstrained binary optimization (QUBO) solvers can be applied to design an optimal structure to avoid resonance. QUBO algorithms that work on a classical or quantum device have succeeded in some industrial applications. However,…

Mesoscale and Nanoscale Physics · Physics 2022-09-29 Tadayoshi Matsumori , Masato Taki , Tadashi Kadowaki

A major obstacle for quantum optimizers is the reformulation of constraints as a quadratic unconstrained binary optimization (QUBO). Current QUBO translators exaggerate the weight $M$ of the penalty terms. Classically known as the "Big-$M$"…

We introduce a novel quadratic unconstrained binary optimization (QUBO) formulation for a classical problem in electrical engineering -- the optimal reconfiguration of distribution grids. For a given graph representing the grid…

Quantum Physics · Physics 2023-01-31 Filipe F. C. Silva , Pedro M. S. Carvalho , Luis A. F. M. Ferreira , Yasser Omar

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. This paper proposes hybrid models and methods that…

Quantum Physics · Physics 2019-11-12 Akshay Ajagekar , Travis Humble , Fengqi You

Encoding combinatorial optimization problems into physically meaningful Hamiltonians with tractable energy landscapes forms the foundation of quantum optimization. Numerous works have studied such efficient encodings for the class of…

Quantum Physics · Physics 2026-02-12 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

Recent studies suggest that gradient-based methods applied to relaxed box-constrained Quadratic Unconstrained Binary Optimization (QUBO) formulations can outperform classical heuristics in some large-scale regimes, often relying on heavy…

Discrete Mathematics · Computer Science 2026-05-11 Yongliang Sun , Ismail Alkhouri , Cheng-Han Huang , Alvaro Velasquez , Susmit Jha , Rongrong Wang

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

In this paper, we propose a learning-to-optimize (L2O) framework to accelerate solving parametric mixed-integer quadratic programming (MIQP) problems, with a particular focus on mixed-integer model predictive control (MI-MPC) applications.…

Systems and Control · Electrical Eng. & Systems 2026-05-14 Viet-Anh Le , Mu Xie , Rahul Mangharam

We present QUBO.jl, an end-to-end Julia package for working with QUBO (Quadratic Unconstrained Binary Optimization) instances. This tool aims to convert a broad range of JuMP problems for straightforward application in many physics and…

Optimization and Control · Mathematics 2023-09-04 Pedro Maciel Xavier , Pedro Ripper , Tiago Andrade , Joaquim Dias Garcia , Nelson Maculan , David E. Bernal Neira

The Quantum Approximate Optimization Algorithm (QAOA) requires considered optimization problems to be translated into a compatible format. A popular transformation step in this pipeline involves the quadratization of higher-order binary…

Quantum Physics · Physics 2025-11-26 Damian Rovara , Lukas Burgholzer , Robert Wille

The Benders' decomposition algorithm is a technique in mathematical programming for complex mixed-integer linear programming (MILP) problems with a particular block structure. The strategy of Benders' decomposition can be described as a…

Optimization and Control · Mathematics 2021-12-16 Zhongqi Zhao , Lei Fan , Zhu Han

We present a hybrid classical-quantum framework based on the Frank-Wolfe algorithm, Q-FW, for solving quadratic, linearly-constrained, binary optimization problems on quantum annealers (QA). The computational premise of quantum computers…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Alp Yurtsever , Tolga Birdal , Vladislav Golyanik

Quadratic unconstrained binary optimization problems (QUBOs) are intensively discussed in the realm of quantum computing and polynomial optimization. We provide a vast experimental study of semidefinite programming (SDP) relaxations of…

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