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A major challenge in computed tomography (CT) is how to minimize patient radiation exposure without compromising image quality and diagnostic performance. The use of deep convolutional (Conv) neural networks for noise reduction in Low-Dose…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Chenyu You , Linfeng Yang , Yi Zhang , Ge Wang

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

Image denoising aims to remove noise while preserving structural details and perceptual realism, yet distortion-driven methods often produce over-smoothed reconstructions, especially under strong noise and distribution shift. This paper…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Nam Nguyen , Thinh Nguyen , Bella Bose

CT scans are the standard-of-care for many clinical ailments, and are needed for treatments like external beam radiotherapy. Unfortunately, CT scanners are rare in low and mid-resource settings due to their costs. Planar X-ray radiography…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Yiran Sun , Tucker Netherton , Laurence Court , Ashok Veeraraghavan , Guha Balakrishnan

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Computed Tomography is one of the efficient and vital modalities of non-destructive techniques (NDT). Various factors influence the CT reconstruction result, including limited projection data, detector electronics optimization, background…

Image and Video Processing · Electrical Eng. & Systems 2022-05-31 Kajal Kumari , Mayank Goswami

Spectral computed tomography (CT) has a great superiority in lesion detection, tissue characterization and material decomposition. To further extend its potential clinical applications, in this work, we propose an improved tensor dictionary…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Weiwen Wu , Yanbo Zhang , Qian Wang , Fenglin Liu , Peijun Chen , Hengyong Yu

Spectral computed tomography based on a photon-counting detector (PCD) attracts more and more attentions since it has the capability to provide more accurate identification and quantitative analysis for biomedical materials. The limited…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Xiaodong Guo , Longhui Li , Dingyue Chang , Peng He , Peng Feng , Hengyong Yu , Weiwen Wu

Deep learning models have significantly improved the visual quality and accuracy on compressive sensing recovery. In this paper, we propose an algorithm for signal reconstruction from compressed measurements with image priors captured by a…

Machine Learning · Computer Science 2020-03-20 Shaojie Xu , Sihan Zeng , Justin Romberg

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Recently, generative diffusion priors have made huge strides as inverse problem solvers, including the ability to be adapted for inference on out-of-distribution data. Concurrently, implicit neural representations (INRs) have emerged as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qiaoqiao Ding , Yuesong Nan , Hao Gao , Hui Ji

In coronary CT angiography, a series of CT images are taken at different levels of radiation dose during the examination. Although this reduces the total radiation dose, the image quality during the low-dose phases is significantly…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Eunhee Kang , Hyun Jung Koo , Dong Hyun Yang , Joon Bum Seo , Jong Chul Ye

Since 2016, deep learning (DL) has advanced tomographic imaging with remarkable successes, especially in low-dose computed tomography (LDCT) imaging. Despite being driven by big data, the LDCT denoising and pure end-to-end reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Wenjun Xia , Hongming Shan , Ge Wang , Yi Zhang

Total-variation (TV)-based Computed Tomography (CT) image reconstruction has shown experimentally to be capable of producing accurate reconstructions from sparse-view data. In particular TV-based reconstruction is very well suited for…

Radiomics is an active area of research focusing on high throughput feature extraction from medical images with a wide array of applications in clinical practice, such as clinical decision support in oncology. However, noise in low dose…

Quantitative Methods · Quantitative Biology 2021-09-07 Junhua Chen , Inigo Bermejo , Andre Dekker , Leonard Wee

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

This paper proposes a new framework to regularize the highly ill-posed and non-linear phase retrieval problem through deep generative priors using simple gradient descent algorithm. We experimentally show effectiveness of proposed algorithm…

Machine Learning · Computer Science 2018-08-20 Fahad Shamshad , Ali Ahmed

Limited-angle X-ray tomography reconstruction is an ill-conditioned inverse problem in general. Especially when the projection angles are limited and the measurements are taken in a photon-limited condition, reconstructions from classical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Zhen Guo , Jung Ki Song , George Barbastathis , Michael E. Glinsky , Courtenay T. Vaughan , Kurt W. Larson , Bradley K. Alpert , Zachary H. Levine

Image reconstruction in Multispectral Computed Tomography (MSCT) requires solving a challenging nonlinear inverse problem, commonly tackled via iterative optimization algorithms. Existing methods necessitate computing the derivative of the…

Numerical Analysis · Mathematics 2024-02-20 Thomas Prohaszka , Lukas Neumann , Markus Haltmeier