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Background: Mutations in KMT2B are a recognized cause of early-onset complex dystonia, with deep brain stimulation (DBS) of the internal globus pallidus (GPi-DBS) being an effective treatment. However, gait impairment, particularly freezing…
Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…
Parkinson's Disease (PD) is a slowly evolving neuro-logical disease that affects about 1% of the population above 60 years old, causing symptoms that are subtle at first, but whose intensity increases as the disease progresses. Automated…
Gait analysis is crucial for the diagnosis and monitoring of movement disorders like Parkinson's Disease. While computer vision models have shown potential for objectively evaluating parkinsonian gait, their effectiveness is limited by…
Parkinsons Disease is a neurological disorder and prevalent in elderly people. Traditional ways to diagnose the disease rely on in-person subjective clinical evaluations on the quality of a set of activity tests. The high-resolution…
Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…
Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…
Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…
Parkinsons disease, PD, is a chronic condition that affects motor skills and includes symptoms like tremors and rigidity. The current diagnostic procedure uses patient assessments to evaluate symptoms and sometimes a magnetic resonance…
Wearable technology for the automatic detection of gait events has recently gained growing interest, enabling advanced analyses that were previously limited to specialist centres and equipment (e.g., instrumented walkway). In this study, we…
Parkinson's disease ranks as the second most prevalent neurodegenerative disorder globally. This research aims to develop a system leveraging Mixed Reality capabilities for tracking and assessing eye movements. In this paper, we present a…
Gait encodes rich biometric and behavioural information, yet leveraging the manner of walking to infer psychological traits remains a challenging and underexplored problem. We introduce a hierarchical Multi-Stage Mixture of Movement Experts…
Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…
Frailty is a condition in aging medicine characterized by diminished physiological reserve and increased vulnerability to stressors. However, frailty assessment remains subjective, heterogeneous, and difficult to scale in clinical practice.…
Video-based gait analysis has become a promising approach for assessing motor impairment in children with cerebral palsy (CP). However, existing methods usually rely on either pose sequences or handcrafted gait features alone, making it…
Scoliosis is a spinal curvature disorder that is difficult to detect early and can compress the chest cavity, impacting respiratory function and cardiac health. Especially for adolescents, delayed detection and treatment result in worsening…
Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…
In this work we develop a new method of diagnosing the nervous system diseases and a new approach in studying human gait dynamics with the help of the theory of discrete non-Markov random processes. The stratification of the phase clouds…
Gait is increasingly recognized as a vital sign, yet current approaches treat it as a symptom of specific pathologies rather than a systemic biomarker. We developed a gait foundation model for 3D skeletal motion from 3,414 deeply phenotyped…
Forensic gait analysis can aid the investigation of crimes through comparing features of gait captured in video footage. Modelling the probative value of gait evidence requires an understanding of the variation of features of gait between…