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Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Aqib Nazir Mir , Iqra Nissar , Mumtaz Ahmed , Sarfaraz Masood , Danish Raza Rizvi

Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…

Medical Physics · Physics 2021-11-25 Simoni Mishra

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Nabil Daiyan , Md Rakibul Haque

The speech of people with Parkinson's Disease (PD) has been shown to hold important clues about the presence and progression of the disease. We investigate the factors based on which humans experts make judgments of the presence of disease…

The use of smartphone and wearable sensing technology for objective, non-invasive and remote clinimetric testing of symptoms has considerable potential. However, the clinimetric accuracy achievable with such technology is highly reliant on…

Signal Processing · Electrical Eng. & Systems 2017-11-27 Reham Badawy , Yordan P. Raykov , Max A. Little

Parkinsons disease, the fastest growing neurodegenerative disorder globally, has seen a 50 percent increase in cases within just two years. As speech, memory, and motor symptoms worsen over time, early diagnosis is crucial for preserving…

Quantitative Methods · Quantitative Biology 2024-12-02 Diya Vatsavai , Anya Iyer , Ashwin A. Nair

We present a web-based framework to screen for Parkinson's disease (PD) by allowing users to perform neurological tests in their homes. Our web framework guides the users to complete three tasks involving speech, facial expression, and…

Human-Computer Interaction · Computer Science 2023-11-22 Md Saiful Islam , Sangwu Lee , Abdelrahman Abdelkader , Sooyong Park , Ehsan Hoque

Parkinson's disease (PD) is one of the most common neurodegenerative disorder. PD telemonitoring emerges as a novel assessment modality enabling self-administered at-home tests of Unified Parkinson's Disease Rating Scale (UPDRS) scores,…

Machine Learning · Computer Science 2025-10-03 Ziming Tang , Chengbin Hou , Tianyu Zhang , Bangxu Tian , Jinbao Wang , Hairong Lv

Parkinson's disease (PD) is debilitating, progressive, and clinically marked by motor symptoms. As the second most common neurodegenerative disease in the world, it affects over 10 million lives globally. Existing diagnoses methods have…

Machine Learning · Computer Science 2021-11-30 Riya Tyagi , Tanish Tyagi , Ming Wang , Lujin Zhang

In this paper, we introduce a novel approach for diagnosis of Parkinson's Disease (PD) based on deep Echo State Networks (ESNs). The identification of PD is performed by analyzing the whole time-series collected from a tablet device during…

Machine Learning · Computer Science 2018-02-20 Claudio Gallicchio , Alessio Micheli , Luca Pedrelli

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Objective measurements of motor signs are of vital importance for diagnosing, monitoring and developing disease modifying…

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…

Neurons and Cognition · Quantitative Biology 2026-04-01 Siyuan Du , Siyi Li , Shuwei Bai , Ang Li , Haolin Li , Mingqing Xiao , Yang Pan , Dongsheng Li , Weidi Xie , Yanfeng Wang , Ya Zhang , Chencheng Zhang , Jiangchao Yao

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

Quantitative Methods · Quantitative Biology 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

In this work we propose a new biophysical computational model of brain regions relevant to Parkinson's Disease based on local field potential data collected from the brain of marmoset monkeys. Parkinson's disease is a neurodegenerative…

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

Machine Learning · Computer Science 2024-06-12 Ashwin Ram

Severity assessment of Parkinson's disease (PD) using wearable sensors offers an effective, objective basis for clinical management. However, general-purpose time series models often lack pathological specificity in feature extraction,…

Machine Learning · Computer Science 2025-10-14 Weiming Zhao , Xulong Wang , Jun Qi , Yun Yang , Po Yang

Parkinson's disease (PD) is a slowly progressive, debilitating neurodegenerative disease which causes motor symptoms including gait dysfunction. Motor fluctuations are alterations between periods with a positive response to levodopa therapy…

Signal Processing · Electrical Eng. & Systems 2023-08-07 Ferdian Jovan , Catherine Morgan , Ryan McConville , Emma L. Tonkin , Ian Craddock , Alan Whone

Parkinson's Disease (PD) is associated with gait movement disorders, such as bradykinesia, stiffness, tremors and postural instability, caused by progressive dopamine deficiency. Today, some approaches have implemented learning…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Edgar Rangel , Fabio Martinez

Limited accessibility to neurological care leads to underdiagnosed Parkinson's Disease (PD), preventing early intervention. Existing AI-based PD detection methods primarily focus on unimodal analysis of motor or speech tasks, overlooking…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Md Saiful Islam , Tariq Adnan , Jan Freyberg , Sangwu Lee , Abdelrahman Abdelkader , Meghan Pawlik , Cathe Schwartz , Karen Jaffe , Ruth B. Schneider , E Ray Dorsey , Ehsan Hoque
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