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Deep learning has been successfully applied to recognizing both natural images and medical images. However, there remains a gap in recognizing 3D neuroimaging data, especially for psychiatric diseases such as schizophrenia and depression…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Mengjiao Hu , Xudong Jiang , Kang Sim , Juan Helen Zhou , Cuntai Guan

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Gene expression represents a fundamental interface between genes and environment in the development and ongoing plasticity of the human organism. Individual differences in gene expression are likely to underpin much of human diversity,…

Genomics · Quantitative Biology 2019-05-31 Akram Yazdani , Raul Mendez Giraldez , Ahmad Samiei

One notable method for recording brainwaves to identify neurological problems is electroencephalography (hereafter EEG). A trained neuro physician can learn more about how the brain functions through the use of EEGs. However conventionally,…

Neurons and Cognition · Quantitative Biology 2024-02-26 Hari Prasad SV

Machine learning models have been successfully employed in the diagnosis of Schizophrenia disease. The impact of classification models and the feature selection techniques on the diagnosis of Schizophrenia have not been evaluated. Here, we…

Machine Learning · Computer Science 2022-07-05 M. Tanveer , Jatin Jangir , M. A. Ganaie , Iman Beheshti , M. Tabish , Nikunj Chhabra

This study investigates the speech articulatory coordination in schizophrenia subjects exhibiting strong positive symptoms (e.g. hallucinations and delusions), using two distinct channel-delay correlation methods. We show that the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-18 Yashish M. Siriwardena , Chris Kitchen , Deanna L. Kelly , Carol Espy-Wilson

Schizophrenia is a globally prevalent psychiatric disorder that severely impairs daily life. Schizophrenia is caused by dopamine imbalances in the fronto-striatal pathways of the brain, which influences fine motor control in the cerebellum.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Rafael Castro , Ishaan Patel , Tarun Patanjali , Priya Iyer

Deep reinforcement learning (DRL) algorithms have the potential to provide new insights into psychiatric disorders. Here we create a DRL model of schizophrenia: a complex psychotic disorder characterized by anhedonia, avoidance, temporal…

Neurons and Cognition · Quantitative Biology 2025-10-30 Xena Al-Hejji , Santina Duarte , Jose Guillermo Gomez Castro , Edgar Bermudez Contreras , Eric Chalmers

This paper proposes \textit{layer fusion} - a model compression technique that discovers which weights to combine and then fuses weights of similar fully-connected, convolutional and attention layers. Layer fusion can significantly reduce…

Machine Learning · Computer Science 2020-07-30 James O' Neill , Greg Ver Steeg , Aram Galstyan

The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

Neuroimaging studies based on magnetic resonance imaging (MRI) typically employ rigorous forms of preprocessing. Images are spatially normalized to a standard template using linear and non-linear transformations. Thus, one can assume that a…

Computer Vision and Pattern Recognition · Computer Science 2019-11-15 Fabian Eitel , Jan Philipp Albrecht , Friedemann Paul , Kerstin Ritter

Convolutional neural networks (CNNs) have had great success in many real-world applications and have also been used to model visual processing in the brain. However, these networks are quite brittle - small changes in the input image can…

Neurons and Cognition · Quantitative Biology 2018-10-30 Brian Hu , Stefan Mihalas

Functional connectivity plays an essential role in modern neuroscience. The modality sheds light on the brain's functional and structural aspects, including mechanisms behind multiple pathologies. One such pathology is schizophrenia which…

Neurons and Cognition · Quantitative Biology 2022-06-07 Maksim Zhdanov , Saskia Steinmann , Nico Hoffmann

Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic…

Convolutional Neural Networks (CNN) increase depth by stacking convolutional layers, and deeper network models perform better in image recognition. Empirical research shows that simply stacking convolutional layers does not make the network…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Rui-Yang Ju , Jen-Shiun Chiang , Chih-Chia Chen , Yu-Shian Lin

Shallow supervised 1-hidden layer neural networks have a number of favorable properties that make them easier to interpret, analyze, and optimize than their deep counterparts, but lack their representational power. Here we use 1-hidden…

Machine Learning · Computer Science 2019-04-24 Eugene Belilovsky , Michael Eickenberg , Edouard Oyallon

The coincidence similarity index, based on a combination of the Jaccard and overlap similarity indices, has noticeable properties in comparing and classifying data, including enhanced selectivity and sensitivity, intrinsic normalization,…

Neural and Evolutionary Computing · Computer Science 2023-08-29 Alexandre Benatti , Luciano da Fontoura Costa

We analyze recurrent neural networks with diagonal hidden-to-hidden weight matrices, trained with gradient descent in the supervised learning setting, and prove that gradient descent can achieve optimality \emph{without} massive…

Machine Learning · Computer Science 2024-10-11 Semih Cayci , Atilla Eryilmaz

The literature manifests that schizophrenia is associated with alterations in brain network connectivity. We investigate whether large-scale Extended Granger Causality (lsXGC) can capture such alterations using resting-state fMRI data. Our…

Neurons and Cognition · Quantitative Biology 2021-01-27 Axel Wismüller , M. Ali Vosoughi

In a hybrid neural network, the expensive convolutional layers are replaced by a non-trainable fixed transform with a great reduction in parameters. In previous works, good results were obtained by replacing the convolutions with wavelets.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Manny Ko , Ujjawal K. Panchal , Héctor Andrade-Loarca , Andres Mendez-Vazquez