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Self-adaptive software systems are often structured into an adaptation engine that manages an adaptable software by operating on a runtime model that represents the architecture of the software (model-based architectural self-adaptation).…

Software Engineering · Computer Science 2018-04-04 Thomas Vogel

Model-driven development is a pragmatic approach to software development that embraces domain-specific languages (DSLs), where models correspond to DSL programs. A distinguishing feature of model-driven development is that clients of a…

Software Engineering · Computer Science 2017-04-03 Sebastian Erdweg , Klaus Ostermann

The paper describes problem-oriented approach to software development. The approach is a part of the original integrated methodology of enterprise Internet-based software design and implementation. All aspects of software development, from…

Software Engineering · Computer Science 2007-05-23 Sergey V. Zykov

Artificial intelligence (AI) has the potential to transform healthcare by supporting more accurate diagnoses and personalized treatments. However, its adoption in practice remains constrained by fragmented data sources, strict privacy…

Software Engineering · Computer Science 2026-02-16 Mira Raheem , Amal Elgammal , Michael Papazoglou , Bernd Krämer , Neamat El-Tazi

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

The application of large language models (LLMs) in healthcare has gained significant attention due to their ability to process complex medical data and provide insights for clinical decision-making. These models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Amna Khalid , Ayma Khalid , Umar Khalid

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

This report documents the development and evaluation of domain-specific language models for neurology. Initially focused on building a bespoke model, the project adapted to rapid advances in open-source and commercial medical LLMs, shifting…

Computation and Language · Computer Science 2025-06-09 Henry Watkins

With the growing interest in quantum computing, the emergence of quantum supremacy has marked a pivotal milestone in the field. As a result, numerous quantum programming languages (QPLs) have been introduced to support the development of…

Software Engineering · Computer Science 2025-10-21 Xiaoyu Guo , Shinobu Saito , Jianjun Zhao

Today, software-intensive systems are increasingly being developed in a globally distributed way. However, besides its benefit, global development also bears a set of risks and problems. One critical factor for successful project management…

Software Engineering · Computer Science 2013-12-12 Ansgar Lamersdorf , Jürgen Münch , Dieter Rombach

Electronic medical records (EMR) contain longitudinal information about patients that can be used to analyze outcomes. Typically, studies on EMR data have worked with established variables that have already been acknowledged to be…

Machine Learning · Computer Science 2017-11-30 Prithwish Chakraborty , Vishrawas Gopalakrishnan , Sharon M. H. Alford , Faisal Farooq

The imbalance between the supply and demand of healthcare resources is a global challenge, which is particularly severe in developing countries. Governments and academic communities have made various efforts to increase healthcare supply…

Computers and Society · Computer Science 2023-06-02 Yi Yu , Shengyue Yao , Kexin Wang , Yan Chen , Fei-Yue Wang , Yilun Lin

The widespread adoption of Electronic Health Record (EHR) systems in healthcare institutes has generated vast amounts of medical data, offering significant opportunities for improving healthcare services through deep learning techniques.…

Machine Learning · Computer Science 2024-01-23 Suhan Cui , Jiaqi Wang , Yuan Zhong , Han Liu , Ting Wang , Fenglong Ma

Software systems development nowadays has moved towards dynamic composition of services that run on distributed infrastructures aligned with continuous changes in the system requirements. Consequently, software developers need to tailor…

Software Engineering · Computer Science 2020-05-12 Mahdi Fahmideh , Mohsen Sharifi , Fereidoon Shams , Hasan Haghighi

In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Christoph Fürböck , Paul Weiser , Branko Mitic , Philipp Seeböck , Thomas Helbich , Georg Langs

Electronic Health Records (EHRs) contain rich temporal dynamics that conventional encoding approaches fail to adequately capture. While Large Language Models (LLMs) show promise for EHR modeling, they struggle to reason about sequential…

Artificial Intelligence · Computer Science 2025-10-01 Zekai Chen , Arda Pekis , Kevin Brown

Substantial increase in the use of Electronic Health Records (EHRs) has opened new frontiers for predictive healthcare. However, while EHR systems are nearly ubiquitous, they lack a unified code system for representing medical concepts.…

Machine Learning · Computer Science 2022-03-21 Kyunghoon Hur , Jiyoung Lee , Jungwoo Oh , Wesley Price , Young-Hak Kim , Edward Choi

[Context] Systems incorporating Machine Learning (ML) models, often called ML-enabled systems, have become commonplace. However, empirical evidence on how ML-enabled systems are engineered in practice is still limited, especially for…

Building and maintaining production-grade ML-enabled components is a complex endeavor that goes beyond the current approach of academic education, focused on the optimization of ML model performance in the lab. In this paper, we present a…

Software Engineering · Computer Science 2023-09-07 Filippo Lanubile , Silverio Martínez-Fernández , Luigi Quaranta

Development and maintenance of Web application is still a complex and error-prone process. We need integrated techniques and tool support for automated generation of Web systems and a ready prescription for easy maintenance. The MDA…

Software Engineering · Computer Science 2011-09-14 M'hamed Rahmouni