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High-dimensional data are crucial in biomedical research. Integrating such data from multiple studies is a critical process that relies on the choice of advanced statistical models, enhancing statistical power, reproducibility, and…

Applications · Statistics 2025-06-24 Mavis Liang , Blake Hansen , Alejandra Avalos-Pacheco , Roberta De Vito

We propose a theoretical formalism, molecular finite automata (MFA), to describe individual proteins as rule-based computing machines. The MFA formalism provides a framework for modeling individual protein behaviors and systems-level…

Quantitative Methods · Quantitative Biology 2010-09-16 Jin Yang , Xin Meng , William S. Hlavacek

Likelihood-free methods are an essential tool for performing inference for implicit models which can be simulated from, but for which the corresponding likelihood is intractable. However, common likelihood-free methods do not scale well to…

Methodology · Statistics 2022-07-15 Christopher Drovandi , David J Nott , David T Frazier

We revisit the problem of computing submatrices of the Cram\'er-Rao bound (CRB), which lower bounds the variance of any unbiased estimator of a vector parameter $\vth$. We explore iterative methods that avoid direct inversion of the Fisher…

Information Theory · Computer Science 2015-06-04 Paul Tune

Data fusion models based on Coupled Matrix and Tensor Factorizations (CMTF) have been effective tools for joint analysis of data from multiple sources. While the vast majority of CMTF models are based on the strictly multilinear…

Machine Learning · Computer Science 2025-06-17 Carla Schenker , Xiulin Wang , David Horner , Morten A. Rasmussen , Evrim Acar

We present the finite amplitude method (FAM) for superfluid systems. A Hartree-Fock-Bogoliubov code may be transformed into a code of the quasi-particle-random-phase approximation (QRPA) with simple modifications. This technique has…

Nuclear Theory · Physics 2011-08-08 Paolo Avogadro , Takashi Nakatsukasa

The classical universal approximation (UA) theorem for neural networks establishes mild conditions under which a feedforward neural network can approximate a continuous function $f$ with arbitrary accuracy. A recent result shows that neural…

Machine Learning · Computer Science 2026-01-28 Geonho Hwang , Wonyeol Lee , Yeachan Park , Sejun Park , Feras Saad

Accurate auto-formalization of theorem statements is essential for advancing automated discovery and verification of research-level mathematics, yet remains a major bottleneck for LLMs due to hallucinations, semantic mismatches, and their…

Artificial Intelligence · Computer Science 2025-10-07 Hanyu Wang , Ruohan Xie , Yutong Wang , Guoxiong Gao , Xintao Yu , Bin Dong

Boolean matrix factorization (BMF) approximates a given binary input matrix as the product of two smaller binary factors. Unlike binary matrix factorization based on standard arithmetic, BMF employs the Boolean OR and AND operations for the…

Information Retrieval · Computer Science 2025-12-05 Christos Kolomvakis , Thomas Bobille , Arnaud Vandaele , Nicolas Gillis

Rational approximation is a powerful tool to obtain accurate surrogates for nonlinear functions that are easy to evaluate and linearize. The interpolatory adaptive Antoulas--Anderson (AAA) method is one approach to construct such…

Numerical Analysis · Mathematics 2024-06-27 Stefan Güttel , Daniel Kressner , Bart Vandereycken

Federated Learning (FL) coordinates with numerous heterogeneous devices to collaboratively train a shared model while preserving user privacy. Despite its multiple advantages, FL faces new challenges. One challenge arises when devices drop…

Machine Learning · Computer Science 2021-06-09 Xinran Gu , Kaixuan Huang , Jingzhao Zhang , Longbo Huang

The inferential models (IM) framework provides prior-free, frequency-calibrated, posterior probabilistic inference. The key is the use of random sets to predict unobservable auxiliary variables connected to the observable data and unknown…

Statistics Theory · Mathematics 2016-01-26 Ryan Martin , Chuanhai Liu

Algorithms are increasingly used to aid with high-stakes decision making. Yet, their predictive ability frequently exhibits systematic variation across population subgroups. To assess the trade-off between fairness and accuracy using finite…

Econometrics · Economics 2025-06-17 Yiqi Liu , Francesca Molinari

Feedback Alignment (FA) methods are biologically inspired local learning rules for training neural networks with reduced communication between layers. While FA has potential applications in distributed and privacy-aware ML, limitations in…

Machine Learning · Computer Science 2024-06-05 Zachary Robertson , Oluwasanmi Koyejo

Interactive theorem provers (ITPs) require manual formalization, which is labor-intensive and demands expert knowledge. While automated formalization offers a potential solution, it faces two major challenges: model hallucination (e.g.,…

Artificial Intelligence · Computer Science 2026-03-24 Wangyue Lu , Lun Du , Sirui Li , Ke Weng , Haozhe Sun , Hengyu Liu , Minghe Yu , Tiancheng Zhang , Ge Yu

The "Inertial Forward-Backward algorithm" (IFB) is a powerful tool for convex nonsmooth minimization problems, it gives the well known "fast iterative shrinkage-thresholding algorithm " (FISTA), which enjoys $O\left( {\frac{1}{{{k^2}}}}…

Optimization and Control · Mathematics 2022-02-25 Hongwei Liu , Ting Wang , Zexian Liu

Accurate estimation such as cost estimation, quality estimation and risk analysis is a major issue in management. We propose a patent pending soft computing framework to tackle this challenging problem. Our generic framework is independent…

Software Engineering · Computer Science 2015-08-04 Danny Ho , Luiz Fernando Capretz , Xishi Huang , Jing Ren

The prior independent framework for algorithm design considers how well an algorithm that does not know the distribution of its inputs approximates the expected performance of the optimal algorithm for this distribution. This paper gives a…

Computer Science and Game Theory · Computer Science 2021-07-13 Jason Hartline , Aleck Johnsen

Gene expression data matrices often contain missing expression values. In this paper, we describe a new algorithm, named improved fixed rank approximation algorithm (IFRAA), for missing values estimations of the large gene expression data…

Genomics · Quantitative Biology 2007-05-23 Shmuel Friedland , Mostafa Kaveh , Amir Niknejad , Hossein Zare

Good sparse approximations are essential for practical inference in Gaussian Processes as the computational cost of exact methods is prohibitive for large datasets. The Fully Independent Training Conditional (FITC) and the Variational Free…

Machine Learning · Statistics 2017-05-31 Matthias Bauer , Mark van der Wilk , Carl Edward Rasmussen