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Feature selection is essential in the analysis of molecular systems and many other fields, but several uncertainties remain: What is the optimal number of features for a simplified, interpretable model that retains essential information?…

Machine Learning · Computer Science 2025-01-22 Romina Wild , Felix Wodaczek , Vittorio Del Tatto , Bingqing Cheng , Alessandro Laio

Robust local feature representations are essential for spatial intelligence tasks such as robot navigation and augmented reality. Establishing reliable correspondences requires descriptors that provide both high discriminative power and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Haodi Yao , Fenghua He , Ning Hao , Yao Su

Feature selection is important for high-dimensional data analysis and is non-trivial in unsupervised learning problems such as dimensionality reduction and clustering. The goal of unsupervised feature selection is finding a subset of…

Machine Learning · Computer Science 2024-11-26 Ziheng Sun , Chris Ding , Jicong Fan

\textbf{Background}: Identifying differentially methylated regions (DMRs) is a basic task in DNA methylation analysis. However, due to the different strategies adopted, different DMR sets will be predicted on the same dataset, which poses a…

Quantitative Methods · Quantitative Biology 2024-07-16 Wenjin Zhang , Wenlong Jie , Wanxin Cui , Guihua Duan , You zou , Xiaoqing Peng

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Motivation: A considerable number of data mining approaches for biomedical data analysis, including state-of-the-art associative models, require a form of data discretization. Although diverse discretization approaches have been proposed,…

Quantitative Methods · Quantitative Biology 2021-03-09 Leonardo Alexandre , Rafael S. Costa , Rui Henriques

In the rapidly evolving landscape of medical imaging diagnostics, achieving high accuracy while preserving computational efficiency remains a formidable challenge. This work presents \texttt{DeepMediX}, a groundbreaking, resource-efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Kishore Babu Nampalle , Pradeep Singh , Uppala Vivek Narayan , Balasubramanian Raman

Quantitative information on tumor heterogeneity and cell load could assist in designing effective and refined personalized treatment strategies. It was recently shown by us that such information can be inferred from the diffusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Yi Yin , Kai Breuhahn , Hans-Ulrich Kauczor , Oliver Sedlaczek , Irene E. Vignon-Clementel , Dirk Drasdo

This paper introduces a novel framework for dynamic classification in high dimensional spaces, addressing the evolving nature of class distributions over time or other index variables. Traditional discriminant analysis techniques are…

Methodology · Statistics 2025-02-18 Wenbo Ouyang , Ruiyang Wu , Ning Hao , Hao Helen Zhang

Many medical imaging techniques utilize fitting approaches for quantitative parameter estimation and analysis. Common examples are pharmacokinetic modeling in DCE MRI/CT, ADC calculations and IVIM modeling in diffusion-weighted MRI and…

Subgraph matching is a core task in graph analytics, widely used in domains such as biology, finance, and social networks. Existing top-k diversified methods typically focus on maximizing vertex coverage, but often return results in the…

Databases · Computer Science 2025-11-25 Liuyi Chen , Yuchen Hu , Zhengyi Yang , Xu Zhou , Wenjie Zhang , Kenli Li

We present a systematic study on a new task called dichotomous image segmentation (DIS) , which aims to segment highly accurate objects from natural images. To this end, we collected the first large-scale DIS dataset, called DIS5K, which…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Xuebin Qin , Hang Dai , Xiaobin Hu , Deng-Ping Fan , Ling Shao , Luc Van Gool

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

Feature screening approaches are effective in selecting active features from data with ultrahigh dimensionality and increasing complexity; however, the majority of existing feature screening approaches are either restricted to a univariate…

Methodology · Statistics 2023-05-09 Shaofei Zhao , Guifang Fu

In many applications of X-ray computed tomography, an unsupervised segmentation of the reconstructed 3D volumes forms an important step in the image processing chain for further investigation of the digitized object. Therefore, the goal is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-09 Thomas Lang

Aiming at improving performance of visual classification in a cost-effective manner, this paper proposes an incremental semi-supervised learning paradigm called Deep Co-Space (DCS). Unlike many conventional semi-supervised learning methods…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Ziliang Chen , Keze Wang , Xiao Wang , Pai Peng , Ebroul Izquierdo , Liang Lin

Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…

Quantitative Methods · Quantitative Biology 2022-04-26 Zihan Chen , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

Diagnostic imaging has gained prominence as potential biomarkers for early detection and diagnosis in a diverse array of disorders including cancer. However, existing methods routinely face challenges arising from various factors such as…

Unsupervised learning of feature representations is a challenging yet important problem for analyzing a large collection of multimedia data that do not have semantic labels. Recently proposed neural network-based unsupervised learning…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Takahiko Furuya , Ryutarou Ohbuchi

Clustering is a fundamental unsupervised learning approach. Many clustering algorithms -- such as $k$-means -- rely on the euclidean distance as a similarity measure, which is often not the most relevant metric for high dimensional data…

Machine Learning · Computer Science 2019-10-22 Aude Genevay , Gabriel Dulac-Arnold , Jean-Philippe Vert
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