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In chronic liver disease, liver fibrosis develops as excessive deposition of extracellular matrix macromolecules, predominantly collagens, progressively form fibrous scars that disrupt the hepatic architecture, and fibrosis, iron, and fat…
Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…
Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…
The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…
Breast ultrasound (US) is an effective imaging modality for breast cancer detection and diagnosis. US computer-aided diagnosis (CAD) systems have been developed for decades and have employed either conventional hand-crafted features or…
Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…
AIM To analyse the performance of a deep-learning (DL) algorithm currently deployed as diagnostic decision support software in two NHS Trusts used to identify normal chest x-rays in active clinical pathways. MATERIALS AND METHODS A DL…
Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…
Computer-aided diagnosis (CAD) technology can assist clinicians in evaluating liver lesions and intervening with treatment in time. Although CAD technology has advanced in recent years, the application scope of existing datasets remains…
Heart disease is the leading cause of death worldwide. Currently, 33% of cases are misdiagnosed, and approximately half of myocardial infarctions occur in people who are not predicted to be at risk. The use of Artificial Intelligence could…
Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…
We present a focal liver lesion detection model leveraged by custom-designed multi-phase computed tomography (CT) volumes, which reflects real-world clinical lesion detection practice using a Single Shot MultiBox Detector (SSD). We show…
The UK Biobank Imaging Study has acquired medical scans of more than 40,000 volunteer participants. The resulting wealth of anatomical information has been made available for research, together with extensive metadata including measurements…
Unsupervised pathology detection can be implemented by training a model on healthy data only and measuring the deviation from the training set upon inference, for example with CNN-based feature extraction and one-class classifiers, or…
We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion…
Fibrotic Lung Disease (FLD) is a severe condition marked by lung stiffening and scarring, leading to respiratory decline. High-resolution computed tomography (HRCT) is critical for diagnosing and monitoring FLD; however, fibrosis appears as…
In recent years, data-driven machine learning (ML) methods have revolutionized the computer vision community by providing novel efficient solutions to many unsolved (medical) image analysis problems. However, due to the increasing privacy…
Visualizing disease-induced scarring and fibrosis in the heart on cardiac magnetic resonance (CMR) imaging with contrast enhancement (LGE) is paramount in characterizing disease progression and quantifying pathophysiological substrates of…
The need for CT scan analysis is growing for pre-diagnosis and therapy of abdominal organs. Automatic organ segmentation of abdominal CT scan can help radiologists analyze the scans faster and segment organ images with fewer errors.…
Head Non-contrast computed tomography (NCCT) scan remain the preferred primary imaging modality due to their widespread availability and speed. However, the current standard for manual annotations of abnormal brain tissue on head NCCT scans…