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Deep learning assisted digital pathology has the potential to impact clinical practice in significant ways. In recent studies, deep neural network (DNN) enabled analysis outperforms human pathologists. Increasing sizes and complexity of the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Haowen Zhou , Steven , Lin , Mark Watson , Cory T. Bernadt , Oumeng Zhang , Ramaswamy Govindan , Richard J. Cote , Changhuei Yang

The segmentation of liver lesions is crucial for detection, diagnosis and monitoring progression of liver cancer. However, design of accurate automated methods remains challenging due to high noise in CT scans, low contrast between liver…

Computer Vision and Pattern Recognition · Computer Science 2017-04-11 Jana Lipková , Markus Rempfler , Patrick Christ , John Lowengrub , Bjoern H. Menze

The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2023-11-10 Jiawen Li , Yunqian Huang , Sheng Song , Hongbo Chen , Junni Shi , Duo Xu , Haibin Zhang , Man Chen , Rui Zheng

Focal liver lesions (FLL) are common clinical findings during physical examination. Early diagnosis and intervention of liver malignancies are crucial to improving patient survival. Although the current 3D segmentation paradigm can…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Jiacheng Hao , Xiaoming Zhang , Wei Liu , Xiaoli Yin , Yuan Gao , Chunli Li , Ling Zhang , Le Lu , Yu Shi , Xu Han , Ke Yan

Understanding the progression of cancer is crucial for defining treatments for patients. The objective of this study is to automate the detection of metastatic liver disease from free-style computed tomography (CT) radiology reports. Our…

Machine Learning · Computer Science 2023-10-31 Maede Ashofteh Barabadi , Xiaodan Zhu , Wai Yip Chan , Amber L. Simpson , Richard K. G. Do

Purpose Segmentation of the liver from abdominal computed tomography (CT) image is an essential step in some computer assisted clinical interventions, such as surgery planning for living donor liver transplant (LDLT), radiotherapy and…

Computer Vision and Pattern Recognition · Computer Science 2016-05-11 Fang Lu , Fa Wu , Peijun Hu , Zhiyi Peng , Dexing Kong

We present an automatic method for joint liver lesion segmentation and classification using a hierarchical fine-tuning framework. Our dataset is small, containing 332 2-D CT examinations with lesion annotated into 3 lesion types: cysts,…

Image and Video Processing · Electrical Eng. & Systems 2019-08-01 Michal Heker , Avi Ben-Cohen , Hayit Greenspan

Liver steatosis is known as the abnormal accumulation of lipids within cells. An accurate quantification of steatosis area within the liver histopathological microscopy images plays an important role in liver disease diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Xiaoyuan Guo , Fusheng Wang , George Teodorou , Alton B. Farris , Jun Kong

Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

Training data is the key component in designing algorithms for medical image analysis and in many cases it is the main bottleneck in achieving good results. Recent progress in image generation has enabled the training of neural network…

Computer Vision and Pattern Recognition · Computer Science 2018-11-02 Avi Ben-Cohen , Roey Mechrez , Noa Yedidia , Hayit Greenspan

Staging of liver fibrosis is important in the diagnosis and treatment planning of patients suffering from liver diseases. Current deep learning-based methods using abdominal magnetic resonance imaging (MRI) usually take a sub-region of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Zheyao Gao , Yuanye Liu , Fuping Wu , NanNan Shi , Yuxin Shi , Xiahai Zhuang

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

Medical Physics · Physics 2025-11-06 Yaqi Li , Justin D. Weigand , Charles Puelz , Mette S. Olufsen , Alyssa Taylor-LaPole

Objectives: To develop and evaluate a radiomics machine learning model for detecting liver fibrosis on CT of the liver. Methods: For this retrospective, single-centre study, radiomic features were extracted from Regions of Interest (ROIs)…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Jay J. Yoo , Khashayar Namdar , Sean Carey , Sandra E. Fischer , Chris McIntosh , Farzad Khalvati , Patrik Rogalla

Objectives: to propose a fully-automatic computer-aided diagnosis (CAD) solution for liver lesion characterization, with uncertainty estimation. Methods: we enrolled 400 patients who had either liver resection or a biopsy and was diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Peng Wang , Yuhsuan Wu , Bolin Lai , Xiao-Yun Zhou , Le Lu , Wendi Liu , Huabang Zhou , Lingyun Huang , Jing Xiao , Adam P. Harrison , Ningyang Jia , Heping Hu

In this study, a hybrid method based on an Adaptive Neuro-Fuzzy Inference System (ANFIS) and Particle Swarm Optimization (PSO) for diagnosing Liver disorders (ANFIS-PSO) is introduced. This smart diagnosis method deals with a combination of…

Neural and Evolutionary Computing · Computer Science 2019-10-30 Mina Rajabi , Hajar Sadeghizadeh , Zahra Mola-Amini , Niloofar Ahmadyrad

Pediatric liver tumors are one of the most common solid tumors in pediatrics, with differentiation of benign or malignant status and pathological classification critical for clinical treatment. While pathological examination is the gold…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Wanqi Wang , Chun Yang , Jianbo Shao , Yaokai Zhang , Xuehua Peng , Jin Sun , Chao Xiong , Long Lu , Lianting Hu

Graft-versus-host disease (GVHD) is a rare but often fatal complication in liver transplantation, with a very high mortality rate. By harnessing multi-modal deep learning methods to integrate heterogeneous and imbalanced electronic health…

Machine Learning · Computer Science 2025-11-18 Yushan Jiang , Shuteng Niu , Dongjin Song , Yichen Wang , Jingna Feng , Xinyue Hu , Liu Yang , Cui Tao

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects 30-40% of US adults and is the most common chronic liver disease. Although often asymptomatic, progression can lead to cirrhosis. The objective of the…

Machine Learning · Computer Science 2026-04-13 Mary E. An , Paul M. Griffin , Jonathan G. Stine , Balakrishnan S. Ramakrishna , Soundar R. T. Kumara

Histopathology images are gigapixel-sized and include features and information at different resolutions. Collecting annotations in histopathology requires highly specialized pathologists, making it expensive and time-consuming.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Jin Li , Deepta Rajan , Chintan Shah , Dinkar Juyal , Shreya Chakraborty , Chandan Akiti , Filip Kos , Janani Iyer , Anand Sampat , Ali Behrooz