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Identifying similar protein sequences is a core step in many computational biology pipelines such as detection of homologous protein sequences, generation of similarity protein graphs for downstream analysis, functional annotation and gene…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-01 Oguz Selvitopi , Saliya Ekanayake , Giulia Guidi , Georgios Pavlopoulos , Ariful Azad , Aydin Buluc

Increasingly large data series collections are becoming commonplace across many different domains and applications. A key operation in the analysis of data series collections is similarity search, which has attracted lots of attention and…

Databases · Computer Science 2020-06-23 Karima Echihabi , Kostas Zoumpatianos , Themis Palpanas , Houda Benbrahim

Existing systems dealing with the increasing volume of data series cannot guarantee interactive response times, even for fundamental tasks such as similarity search. Therefore, it is necessary to develop analytic approaches that support…

Databases · Computer Science 2022-12-29 Karima Echihabi , Theophanis Tsandilas , Anna Gogolou , Anastasia Bezerianos , Themis Palpanas

The most useful data mining primitives are distance measures. With an effective distance measure, it is possible to perform classification, clustering, anomaly detection, segmentation, etc. For single-event time series Euclidean Distance…

Machine Learning · Computer Science 2022-12-14 Audrey Der , Chin-Chia Michael Yeh , Renjie Wu , Junpeng Wang , Yan Zheng , Zhongfang Zhuang , Liang Wang , Wei Zhang , Eamonn Keogh

At CCS 2015 Naveed et al. presented first attacks on efficiently searchable encryption, such as deterministic and order-preserving encryption. These plaintext guessing attacks have been further improved in subsequent work, e.g. by Grubbs et…

Cryptography and Security · Computer Science 2017-09-28 Florian Kerschbaum , Anselme Tueno

Social media platforms enable users to share diverse types of information, including geolocation data that captures their movement patterns. Such geolocation data can be leveraged to reconstruct the trajectory of a user's visited Points of…

Databases · Computer Science 2024-09-23 Sara Jarrad , Hubert Naacke , Stephane Gancarski

We propose a family of very efficient hierarchical indexing schemes for ungapped, score matrix-based similarity search in large datasets of short (4-12 amino acid) protein fragments. This type of similarity search has importance in both…

Data Structures and Algorithms · Computer Science 2007-09-04 Aleksandar Stojmirovic , Vladimir Pestov

As a key ingredient of the DBMS, index plays an important role in the query optimization and processing. However, it is a non-trivial task to apply existing indexes or design new indexes for new applications, where both data distribution…

Databases · Computer Science 2020-03-05 Sai Wu , Xinyi Yu , Xiaojie Feng , Feifei Li , Wei Cao , Gang Chen

Unsupervised representation learning approaches aim to learn discriminative feature representations from unlabeled data, without the requirement of annotating every sample. Enabling unsupervised representation learning is extremely crucial…

Machine Learning · Computer Science 2023-08-04 Qianwen Meng , Hangwei Qian , Yong Liu , Yonghui Xu , Zhiqi Shen , Lizhen Cui

Computation in a typical Transformer-based large language model (LLM) can be characterized by batch size, hidden dimension, number of layers, and sequence length. Until now, system works for accelerating LLM training have focused on the…

Machine Learning · Computer Science 2023-10-05 Sam Ade Jacobs , Masahiro Tanaka , Chengming Zhang , Minjia Zhang , Shuaiwen Leon Song , Samyam Rajbhandari , Yuxiong He

Similarity search, the task of identifying objects most similar to a given query object under a specific metric, has gathered significant attention due to its practical applications. However, the absence of coordinate information to…

Databases · Computer Science 2024-05-14 Yifan Zhu , Ruiyao Ma , Baihua Zheng , Xiangyu Ke , Lu Chen , Yunjun Gao

In this vision paper, we propose a shift in perspective for improving the effectiveness of similarity search. Rather than focusing solely on enhancing the data quality, particularly machine learning-generated embeddings, we advocate for a…

Databases · Computer Science 2023-08-03 Renzhi Wu , Jingfan Meng , Jie Jeff Xu , Huayi Wang , Kexin Rong

Nearest neighbor searching of large databases in high-dimensional spaces is inherently difficult due to the curse of dimensionality. A flavor of approximation is, therefore, necessary to practically solve the problem of nearest neighbor…

Databases · Computer Science 2018-04-24 Akhil Arora , Sakshi Sinha , Piyush Kumar , Arnab Bhattacharya

This paper proposes a general framework for matching similar subsequences in both time series and string databases. The matching results are pairs of query subsequences and database subsequences. The framework finds all possible pairs of…

Databases · Computer Science 2012-08-02 Haohan Zhu , George Kollios , Vassilis Athitsos

Next-generation sequencing (NGS) technologies have enabled affordable sequencing of billions of short DNA fragments at high throughput, paving the way for population-scale genomics. Genomics data analytics at this scale requires overcoming…

Databases · Computer Science 2019-10-11 Darryl Ho , Jialin Ding , Sanchit Misra , Nesime Tatbul , Vikram Nathan , Vasimuddin Md , Tim Kraska

Finding the most similar subsequences between two multidimensional time series has many applications: e.g. capturing dependency in stock market or discovering coordinated movement of baboons. Considering one pattern occurring in one time…

Machine Learning · Computer Science 2025-05-19 Thanadej Rattanakornphan , Piyanon Charoenpoonpanich , Chainarong Amornbunchornvej

Text indexing is a fundamental and well-studied problem. Classic solutions either replace the original text with a compressed representation, e.g., the FM-index and its variants, or keep it uncompressed but attach some redundancy - an index…

Data Structures and Algorithms · Computer Science 2026-02-05 Lorraine A. K. Ayad , Gabriele Fici , Ragnar Groot Koerkamp , Grigorios Loukides , Rob Patro , Giulio Ermanno Pibiri , Solon P. Pissis

This paper describes a method to efficiently retrieve protein database sequences similar to a query sequence, while allowing for significant numbers of mutations. We call this method SEQR for SEQuence Retrieval. This approach increases the…

Genomics · Quantitative Biology 2018-11-05 David I. Hurwitz , Lianyi Han , Lewis Y. Geer

Significant efforts have been expended in the research and development of a database management system (DBMS) that has a wide range of applications for managing an enormous collection of multisource, heterogeneous, complex, or growing data.…

Databases · Computer Science 2021-04-01 Chunkai Zhang , Zilin Du , Quanjian Dai , Wensheng Gan , Jian Weng , Philip S. Yu

The time series classification literature has expanded rapidly over the last decade, with many new classification approaches published each year. Prior research has mostly focused on improving the accuracy and efficiency of classifiers,…

Machine Learning · Computer Science 2020-06-03 Thach Le Nguyen , Severin Gsponer , Iulia Ilie , Martin O'Reilly , Georgiana Ifrim