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We propose a scalable, cloud-native architecture designed for Transcriptomics Atlas Pipeline, using a resource-intensive STAR aligner and processing tens or hundreds of terabytes of RNA-seq data. We implement the pipeline using AWS cloud…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-11 Piotr Kica , Sabina Lichołai , Michał Orzechowski , Maciej Malawski

Efficient data management is a key component in achieving good performance for scientific workflows in distributed environments. Workflow applications typically communicate data between tasks using files. When tasks are distributed, these…

Instrumentation and Methods for Astrophysics · Physics 2015-03-17 Gideon Juve , Ewa Deelman , Karan Vahi , Gaurang Mehta , Bruce Berriman , Benjamin P. Berman , Phil Maechling

Commercial cloud platforms are a powerful technology for astronomical research. Despite the benefits of cloud computing -- such as on-demand scalability and reduction of systems management overhead -- confusion over how to manage costs…

Instrumentation and Methods for Astrophysics · Physics 2020-12-16 G. Bruce Berriman , William O'Mullane , Arik Mitschang , Ivelina Momcheva

An array of large observational programs using ground-based and space-borne telescopes is planned in the next decade. The forthcoming wide-field sky surveys are expected to deliver a sheer volume of data exceeding an exabyte. Processing the…

Instrumentation and Methods for Astrophysics · Physics 2023-05-26 Kana Moriwaki , Takahiro Nishimichi , Naoki Yoshida

Historically, high energy physics computing has been performed on large purpose-built computing systems. These began as single-site compute facilities, but have evolved into the distributed computing grids used today. Recently, there has…

Homology is a tool in topological data analysis which measures the shape of the data. In many cases, these measurements translate into new insights which are not available by other means. To compute homology, we rely on mathematical…

Quantum Physics · Physics 2016-06-07 Raouf Dridi , Hedayat Alghassi

Scientific computing often requires the availability of a massive number of computers for performing large scale experiments. Traditionally, these needs have been addressed by using high-performance computing solutions and installed…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-15 Christian Vecchiola , Suraj Pandey , Rajkumar Buyya

Big data analytics has gathered immense research attention lately because of its ability to harness useful information from heaps of data. Cloud computing has been adjudged as one of the best infrastructural solutions for implementation of…

Computers and Society · Computer Science 2017-11-15 Samiya Khan , Mansaf Alam

Cloud computing provisions computer resources at a cost-effective way based on demand. Therefore it has become a viable solution for big data analytics and artificial intelligence which have been widely adopted in various domain science.…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-30 Naweiluo Zhou , Florent Dufour , Vinzent Bode , Peter Zinterhof , Nicolay J Hammer , Dieter Kranzlmüller

Commodity cloud computing, as provided by commercial vendors such as Amazon, Google, and Microsoft, has revolutionized computing in many sectors. With the advent of a new class of big data, public access astronomical facility such as LSST,…

Large-scale astronomical image data processing and prediction are essential for astronomers, providing crucial insights into celestial objects, the universe's history, and its evolution. While modern deep learning models offer high…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Mills Staylor , Amirreza Dolatpour Fathkouhi , Md Khairul Islam , Kaleigh O'Hara , Ryan Ghiles Goudjil , Geoffrey Fox , Judy Fox

We present a calibration component for the Murchison Widefield Array All-Sky Virtual Observatory (MWA ASVO) utilising a newly developed PostgreSQL database of calibration solutions. Since its inauguration in 2013, the MWA has recorded over…

The size of astronomical observational data is increasing yearly. For example, while Atacama Large Millimeter/submillimeter Array is expected to generate 200 TB raw data every year, Large Synoptic Survey Telescope is estimated to produce 15…

Instrumentation and Methods for Astrophysics · Physics 2016-11-21 Satoshi Eguchi

High-dimensional astronomical data cubes provide a wealth of spectral and structural information that can be used to study astrophysical and chemical processes. The complexity and sheer size of these datasets pose significant challenges in…

Instrumentation and Methods for Astrophysics · Physics 2025-12-18 Haley N. Scolati , Ryan A. Loomis , Anthony J. Remijan , Kin Long Kelvin Lee

We investigate the capabilities of cloud computing for large-scale,tightly-coupled simulations of biological fluids in complex geometries, traditionally performed in supercomputing centers. We demonstrate scalable and efficient simulations…

Upcoming and future astronomy research facilities will systematically generate terabyte-sized data sets moving astronomy into the Petascale data era. While such facilities will provide astronomers with unprecedented levels of accuracy and…

Instrumentation and Methods for Astrophysics · Physics 2011-11-30 A. H. Hassan , C. J. Fluke , D. G. Barnes

Scientific analyses commonly compose multiple single-process programs into a dataflow. An end-to-end dataflow of single-process programs is known as a many-task application. Typically, tools from the HPC software stack are used to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-03-15 Zhao Zhang , Kyle Barbary , Frank Austin Nothaft , Evan Sparks , Oliver Zahn , Michael J. Franklin , David A. Patterson , Saul Perlmutter

The Cloud has become a principal paradigm of computing in the last ten years, and Computer Science curricula must be updated to reflect that reality. This paper examines simple ways to accomplish curriculum cloudification using Amazon Web…

Computers and Society · Computer Science 2020-02-11 Michael Soltys

Much like on-premises systems, the natural choice for running database analytics workloads in the cloud is to provision a cluster of nodes to run a database instance. However, analytics workloads are often bursty or low volume, leaving…

Databases · Computer Science 2019-11-27 Matthew Perron , Raul Castro Fernandez , David DeWitt , Samuel Madden

Cloud computing has become increasingly popular. Many options of cloud deployments are available. Testing cloud performance would enable us to choose a cloud deployment based on the requirements. In this paper, we present an innovative…

Performance · Computer Science 2015-09-03 Li Chen , Pooja Jain , Kingsum Chow , Emad Guirguis , Tony Wu