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Recent improvements in high-throughput genotyping and sequencing technologies have afforded the collection of massive, genome-wide datasets of DNA information from hundreds of thousands of individuals. These datasets, in turn, provide…

Populations and Evolution · Quantitative Biology 2014-12-19 Pier Francesco Palamara

At time 0, start a time-continuous binary branching process, where particles give birth to a single particle independently (at a possibly time-dependent rate) and die independently (at a possibly time-dependent and age-dependent rate). A…

Probability · Mathematics 2017-10-09 Amaury Lambert

We describe the simulation method of modelling the population evolution using Monte Carlo based on the Penna model. Individuals in the populations are represented by their diploid genomes. Genes expressed after the minimum reproduction age…

Genomics · Quantitative Biology 2009-01-13 Agnieszka Laszkiewicz , Przemyslaw Biecek , Katarzyna Bonkowska , Stanislaw Cebrat

Consider a branching process with a homogeneous reproduction law. Sampling a single cell uniformly from the population at a time $T > 0$ and looking along the sampled cell's ancestral lineage, we find that the reproduction law is…

Populations and Evolution · Quantitative Biology 2022-05-30 David Cheek , Samuel G. G. Johnston

We consider a general class of Markovian models describing the growth in a randomly fluctuating environment of a clonal biological population having several phenotypes related by stochastic switching. Phenotypes differ e.g. by the level of…

Populations and Evolution · Quantitative Biology 2022-01-25 J. Unterberger

The goal of this article is to contribute towards the conceptual and quantitative understanding of the evolutionary benefits for (microbial) populations to maintain a seed bank (consisting of dormant individuals) when facing fluctuating…

Probability · Mathematics 2024-07-02 Jochen Blath , Felix Hermann , Martin Slowik

We propose in this article a brief description of the work, over almost a decade, resulting from a collaboration between mathematicians and biologists from four different research laboratories, identifiable as the co-authors of the articles…

Populations and Evolution · Quantitative Biology 2023-05-30 Olivier Mazet , Camille Noûs

Neurons within a population are strongly correlated, but how to simply capture these correlations is still a matter of debate. Recent studies have shown that the activity of each cell is influenced by the population rate, defined as the…

Neurons and Cognition · Quantitative Biology 2016-12-26 Christophe Gardella , Olivier Marre , Thierry Mora

We model evolution of plants in a world, made up of different locations, with multiple environments (mutually exclusive and collectively exhaustive subsets of locations). Each environment (landmass) has temperature, rainfall, and other…

Populations and Evolution · Quantitative Biology 2019-05-27 Alexander , Khazatsky , Albert Yu , Zihao Zhao , Gabe Zuckerman

Consider a multitype coalescent process in which each block has a colour in $\{1,\ldots,d\}$. Individual blocks may change colour, and some number of blocks of various colours may merge to form a new block of some colour. We show that if…

Probability · Mathematics 2022-03-08 Samuel G. G. Johnston , Andreas E. Kyprianou , Tim Rogers

The sample frequency spectrum of a segregating site is the probability distribution of a sample of alleles from a genetic locus, conditional on observing the sample to have more than one clearly different phenotypes. We present a model for…

Probability · Mathematics 2014-05-13 Arka Bhattacharya

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

We investigate the behaviour of the genealogy of a Wright-Fisher population model under the influence of a strong seed-bank effect. More precisely, we consider a simple seed-bank age distribution with two atoms, leading to either classical…

Probability · Mathematics 2014-03-13 Jochen Blath , Bjarki Eldon , Adrián González Casanova , Noemi Kurt

The population density and per-generation dispersal rate of a population are central parameters in the study of evolution and ecology. The distribution of recent coalescent events between individuals in space can be used to estimate such…

Populations and Evolution · Quantitative Biology 2025-07-14 Francisco Campuzano Jiménez , Arthur Zwaenepoel , Els Lea R De Keyzer , Hannes Svardal

When two (possibly different in distribution) continuous-state branching processes with immigration are present, we study the relative frequency of one of them when the total mass is forced to be constant at a dense set of times. This leads…

Probability · Mathematics 2023-03-14 María Emilia Caballero , Adrián González Casanova , José-Luis Pérez

Life is a complex biological phenomenon represented by numerous chemical, physical and biological processes performed by a biothermodynamic system/cell/organism. Both living organisms and inanimate objects are subject to aging, a biological…

Other Quantitative Biology · Quantitative Biology 2018-01-25 Marko Popovic

We consider the spatial Lambda-Fleming-Viot process model for frequencies of genetic types in a population living in R^d, in the special case in which there are just two types of individual, labelled 0 and 1. At time zero, everyone in the…

Probability · Mathematics 2011-11-28 N. Berestycki , A. M. Etheridge , A. Veber

We introduce an interacting particle system which models the inherited sterility method. Individuals evolve on $\mathbb{Z}^d$ according to a contact process with parameter $\lambda>0$. With probability $p \in [0,1]$ an offspring is fertile…

Probability · Mathematics 2025-11-18 Sonia Velasco

Consider a population where individuals give birth at constant rate during their lifetimes to i.i.d. copies of themselves. Individuals bear clonally inherited types, but (neutral) mutations may happen at the birth events. The smallest…

Probability · Mathematics 2013-05-29 Cécile Delaporte

We extend the spatial $\Lambda$-Fleming-Viot process introduced in [Electron. J. Probab. 15 (2010) 162-216] to incorporate recombination. The process models allele frequencies in a population which is distributed over the two-dimensional…

Probability · Mathematics 2012-11-28 A. M. Etheridge , A. Véber