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Phase-contrast X-ray imaging can improve the visibility of weakly absorbing objects (e.g. soft tissues) by an order of magnitude or more compared to conventional radiographs. Previously, it has been shown that combining phase retrieval with…

Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…

Medical Physics · Physics 2023-10-18 Juan C. R. Luna , Mini Das

In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…

Medical Physics · Physics 2023-01-23 G. Muti , S. Riga , L. Berta , D. Curto , C. De Mattia , M. Felisi , F. Rizzetto , A. Torresin , A. Vanzulli , P. E. Colombo

Purpose: Developing photon-counting CT detectors requires understanding the impact of parameters such as converter material, absorption length and pixel size. We apply a novel linear-systems framework, incorporating spatial and energy…

Medical Physics · Physics 2020-03-03 Mats Persson , Adam Wang , Norbert J. Pelc

While drastic improvements in CT technology have occurred in the past 25 years, spatial resolution is one area where progress has been limited until recently. New photon counting CT systems, are capable of much better spatial resolution…

In this paper, we present our approach to systematically measure numerous performance parameters of MCP-PMTs. The experimental setups, the analyses and selected results are discussed. Although the techniques used may be different in other…

Instrumentation and Detectors · Physics 2024-07-08 A. Lehmann , M. Böhm , M. Götz , K. Gumbert , S. Krauss , D. Miehling , M. Pfaffinger

Multi-contrast magnetic resonance imaging is a significant and essential medical imaging technique.However, multi-contrast imaging has longer acquisition time and is easy to cause motion artifacts. In particular, the acquisition time for a…

Image and Video Processing · Electrical Eng. & Systems 2023-12-04 Yuxia Huang , Zhonghui Wu , Xiaoling Xu , Minghui Zhang , Shanshan Wang , Qiegen Liu

Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…

Human-Computer Interaction · Computer Science 2025-08-21 Mohit Sharma , Emma Nilsson , Martin Falk , Talha Bin Masood , Lee Jollans , Anders Persson , Tino Ebbers , Ingrid Hotz

Quantitative imaging is an important feature of spectral X-ray and CT systems, especially photon-counting CT (PCCT) imaging systems, which is achieved through material decomposition (MD) using spectral measurements. In this work, we present…

Medical Physics · Physics 2026-03-04 Sen Wang , Yirong Yang , Jooho Lee , Grant M. Stevens , Adam S. Wang

K-edge imaging is commonly used for viewing contrast pharmaceuticals in a variety of multi-energy x-ray imaging techniques, ranging from dual-energy and spectral computed tomography to fluoroscopy. When looking for the K-edge signal of a…

The use of photon counting detection technology has resulted in significant X-ray imaging research interest in recent years. Computed Tomography (CT) scanners can benefit from photon-counting detectors, which are new technology with the…

Instrumentation and Detectors · Physics 2024-01-08 K. Hameed , Rafidah Zainon , Mahbubunnabi Tamal

While contrast-enhanced CT (CECT) is standard for assessing abdominal aortic aneurysms (AAA), the required iodinated contrast agents pose significant risks, including nephrotoxicity, patient allergies, and environmental harm. To reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yuxuan Ou , Ning Bi , Jiazhen Pan , Jiancheng Yang , Boliang Yu , Usama Zidan , Regent Lee , Vicente Grau

Dual-energy computed tomography (CT) is to reconstruct images of an object from two projection datasets generated from two distinct x-ray source energy spectra. It can provide more accurate attenuation quantification than conventional CT…

Medical Physics · Physics 2018-05-15 Wenxiang Cong , Daniel Harrison , Yan Xi , Ge Wang

Photon detection efficiency is a key parameter of PMTs in high-precision neutrino and dark matter experiments, while most of these experiments are focus on quantum efficiency. More and more experiments are trying to know the detection…

Instrumentation and Detectors · Physics 2018-10-12 Hai-qiong Zhang , Zhi-min Wang , Feng-jiao Luo , An-bo Yang , Zhong-hua Qin , Chang-gen Yang , Yue-kun Heng

X-ray phase-contrast imaging has the potential to improve image contrast with lower dose by probing an object's refractive properties as well as its absorptive properties. To reconstruct a phase-contrast image from a raw dataset, a phase…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

For dose calculations in ion beam therapy, it is vital to accurately determine the relative stopping power (RSP) distribution within the treated volume. Currently, RSP values are extrapolated from Hounsfield units (HU), measured with x-ray…

While compressed sensing (CS) based reconstructions have been developed for low-dose CBCT, a clear understanding on the relationship between the image quality and imaging dose at low dose levels is needed. In this paper, we qualitatively…

Medical Physics · Physics 2015-06-03 Hao Yan , Laura Cervino , Xun Jia , Steve B. Jiang

The detection of objects in the presence of significant background noise is a problem of fundamental interest in sensing. In this work, we theoretically analyze a prototype target detection protocol, the quantum temporal correlation (QTC)…

Optics · Physics 2020-04-16 Han Liu , Bhashyam Balaji , Amr S. Helmy

Cone-beam computed tomography (CBCT) offers advantages over conventional fan-beam CT in that it requires a shorter time and less exposure to obtain images. CBCT has found a wide variety of applications in patient positioning for…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 S. Kida , S. Kaji , K. Nawa , T. Imae , T. Nakamoto , S. Ozaki , T. Ohta , Y. Nozawa , K. Nakagawa