Related papers: An Analysis by Synthesis Method that Allows Accura…
Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…
Motion-related artifacts are inevitable in Magnetic Resonance Imaging (MRI) and can bias automated neuroanatomical metrics such as cortical thickness. These biases can interfere with statistical analysis which is a major concern as motion…
We propose a method for estimating the bone mineral density (BMD) from a plain x-ray image. Dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) provide high accuracy in diagnosing osteoporosis; however, these…
Cervical dystonia (CD) is the most common form of dystonia, yet current assessment relies on subjective clinical rating scales, such as the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), which requires expertise, is subjective…
Intravascular ultrasound and optical coherence tomography are widely available for characterizing coronary stenoses and provide critical vessel parameters to optimize percutaneous intervention. Intravascular polarization-sensitive optical…
Osteoporosis causes progressive loss of bone density and strength, causing a more elevated risk of fracture than in normal healthy bones. It is estimated that some 1 in 3 women and 1 in 5 men over the age of 50 will experience osteoporotic…
Automated detection of sclerotic metastases (bone lesions) in Computed Tomography (CT) images has potential to be an important tool in clinical practice and research. State-of-the-art methods show performance of 79% sensitivity or…
Age-related bone loss and postmenopausal osteoporosis are disorders of bone remodelling, in which less bone is reformed than resorbed. Yet, this dysregulation of bone remodelling does not occur equally in all bone regions. Loss of bone is…
Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…
The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired…
The presence of a vertebral compression fracture is highly indicative of osteoporosis and represents the single most robust predictor for development of a second osteoporotic fracture in the spine or elsewhere. Less than one third of…
Deep-learning-based MR-to-CT synthesis can estimate the electron density of tissues, thereby facilitating PET attenuation correction in whole-body PET/MR imaging. However, whole-body MR-to-CT synthesis faces several challenges including the…
Personalized computed tomography (CT) dosimetry has great potential in assessing patient-specific radiation exposure, supporting risk assessment, and optimizing clinical protocols. The aim of this study is to evaluate the potential of…
Bone segmentation is an essential step for the preoperative planning of fracture trauma surgery. The automated segmentation of fractured bone from computed tomography (CT) scans remains challenging, due to the large differences of fractures…
Limited DXA access hinders osteoporosis screening. This proof-of-concept study proposes using widely available knee X-rays for opportunistic Bone Mineral Density (BMD) estimation via deep learning, emphasizing robust uncertainty…
The latest advances in computer-assisted precision medicine are making it feasible to move from population-wide models that are useful to discover aggregate patterns that hold for group-based analysis to patient-specific models that can…
Accuracy validation of cortical thickness measurement is a difficult problem due to the lack of ground truth data. To address this need, many methods have been developed to synthetically induce gray matter (GM) atrophy in an MRI via…
Objective: To demonstrate the effectiveness of using a deep learning-based approach for a fully automated slice-based measurement of muscle mass for assessing sarcopenia on CT scans of the abdomen without any case exclusion criteria.…
MRI-based entorhinal cortical thickness (eCT) measurements predict cognitive decline in Alzheimer's disease (AD) with low cost and minimal invasiveness. Two prominent imaging paradigms, FreeSurfer (FS) and Advanced Normalization Tools…
Osteoporosis induced fractures occur worldwide about every 3 seconds. Vertebral compression fractures are early signs of the disease and considered risk predictors for secondary osteoporotic fractures. We present a detection method to…