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This paper constructs dynamical models and estimation algorithms for the concentration of target molecules in a fluid flow using an array of novel biosensors. Each biosensor is constructed out of protein molecules embedded in a synthetic…
Light-emitting metasurfaces provide a compact, integrated solution for simultaneous light generation and beam shaping, making them a promising candidate for advanced photonic applications. However, existing approaches for tailoring…
The disruption of protein structures by denaturants like urea is well studied, though its molecular mechanisms remain unclear. Using Molecular Dynamics (MD) simulations, we investigated how urea affects the structural stability of Bovine…
Spatial gradients of diffusible signalling molecules play crucial roles in controlling diverse cellular behaviour such as cell differentiation, tissue patterning and chemotaxis. In this paper, we report the design and testing of a…
Advances in methods of biological data collection are driving the rapid growth of comprehensive datasets across clinical and research settings. These datasets provide the opportunity to monitor biological systems in greater depth and at…
In situ polymerization and micropatterning of hydrogels on-chip opens the potential for many applications such as tracking and controlling the diffusion of molecules, stimulants, inhibitors, as well as nutrients and drugs, from their source…
A method is presented for fabrication of femtosecond laser written waveguides in glass to remove the need for polishing of substrates after processing. It is shown that by amplitude masking the fabrication laser beam near the sample edge…
The elasticity of PDMS has played a central role in advancing important microfluidic technologies, ranging from early valves to sophisticated organ-on-a-chip systems. However, most deformable microfluidic devices are based on geometries…
Super-resolution imaging using sub-diffraction field localization by micron sized transparent beads (microspheres) was recently demonstrated [1]. Practical applications in microscopy require control over the positioning of the microspheres.…
Whispering gallery mode (WGM) lasers are well-known for their small sizes, low thresholds and narrow linewidths, and have been the subject of research and development for more than two decades. However most of the initial reports and…
Atomic devices such as atomic clocks and optically-pumped magnetometers rely on the interrogation of atoms contained in a cell whose inner content has to meet high standards of purity and accuracy. Glass-blowing techniques and craftsmanship…
Molecular sieves, such as nanoporous AlPO_4-5, can host a wide variety of laser active dyes. We embedded pyridine 2 molecules as a representative of a commercially available dye which fits into the channel pores of the host matrix. Many…
Plasma-based mid-infrared (MIR) laser generation has garnered significant interest owing to its advantage of high output power, continuous wavelength tunability, and ultrashort pulse durations. However, existing methodologies predominantly…
Viscosity is a key property of cell membranes that controls mobility of embedded proteins and membrane remodeling. Measuring it is challenging because existing approaches involve complex experimental designs and/or models, and the…
The possibility of performing time-resolved spectroscopic studies in the molecular fingerprinting region or extending the cut-off wavelength of high-harmonic generation has recently boosted the development of efficient mid-infrared…
In the demanding biosensing environment, improving selection efficiency strategies has become an issue of great significance. DNA minicircles containing between 200 and 400 base-pairs, also named microDNA, are representative of the…
Colloidosomes are created in the laboratory from a Pickering emulsion of water droplets in oil. The colloidosomes have approximately the same diameter and by choosing (hairy) particles of different diameters it is possible to control the…
We review the computation models for biofilm and bacteria cells, providing perspectives on biofilm's various properties and potential serving as engineering living materials (ELMs), considering the omnipresence of such biological matter.…
A novel microfabricated, all-electrical measurement platform is presented for a direct, accurate and rapid determination of the thermal conductivity and diffusivity of liquid and solid materials. The measurement approach is based on the…
The development of ultrahigh quality factor (Q) microresonators has been driving such technologies as cavity quantum electrodynamics (QED), high-precision sensing, optomechanics, and optical frequency comb generation. Here we report…