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Related papers: Microscope Based HER2 Scoring System

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Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

This paper describes a novel system for automatic classification of images obtained from Anti-Nuclear Antibody (ANA) pathology tests on Human Epithelial type 2 (HEp-2) cells using the Indirect Immunofluorescence (IIF) protocol. The IIF…

Cell Behavior · Quantitative Biology 2014-04-15 Arnold Wiliem , Conrad Sanderson , Yongkang Wong , Peter Hobson , Rodney F. Minchin , Brian C. Lovell

Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression…

Machine Learning · Computer Science 2023-10-24 Matheus del-Valle , Emerson Soares Bernardes , Denise Maria Zezell

Identifying type 2 diabetes mellitus can be challenging, particularly for primary care physicians. Clinical decision support systems incorporating artificial intelligence (AI-CDSS) can assist medical professionals in diagnosing type 2…

Machine Learning · Computer Science 2026-02-13 Mujeeb Ur Rehman , Imran Rehan , Sohail Khalid

It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Peide Zhu , Linbin Lu , Zhiqin Chen , Xiong Chen

The importance of rapid and accurate histologic analysis of surgical tissue in the operating room has been recognized for over a century. Our standard-of-care intraoperative pathology workflow is based on light microscopy and H\&E…

Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Saimunur Rahman , Lei Wang , Changming Sun , Luping Zhou

Recently, there has been great interest in developing Artificial Intelligence (AI) enabled computer-aided diagnostics solutions for the diagnosis of skin cancer. With the increasing incidence of skin cancers, low awareness among a growing…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Manu Goyal , Thomas Knackstedt , Shaofeng Yan , Saeed Hassanpour

The AUTO-PCOS Classification Challenge seeks to advance the diagnostic capabilities of artificial intelligence (AI) in identifying Polycystic Ovary Syndrome (PCOS) through automated classification of healthy and unhealthy ultrasound frames.…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Atharva Divekar , Atharva Sonawane

Cervical spondylosis, a complex and prevalent condition, demands precise and efficient diagnostic techniques for accurate assessment. While MRI offers detailed visualization of cervical spine anatomy, manual interpretation remains…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Lianming Wu , Kun Wang , Jianqi Sun , Hongxing Shen

Real-time computer-aided diagnosis using artificial intelligence (AI), with images, can help oncologists diagnose cancer with high accuracy and in an early phase. We reviewed real-time AI-based analyzed images for decision-making in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Leila Bagheriye , Johan Kwisthout

Supervised deep learning has shown state-of-the-art performance for medical image segmentation across different applications, including histopathology and cancer research; however, the manual annotation of such data is extremely laborious.…

Breast cancer early detection is crucial for improving patient outcomes. The Institut Catal\`a de la Salut (ICS) has launched the DigiPatICS project to develop and implement artificial intelligence algorithms to assist with the diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 David Anglada-Rotger , Ferran Marqués , Montse Pardàs

The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won…

Quantitative Methods · Quantitative Biology 2016-06-21 Dayong Wang , Aditya Khosla , Rishab Gargeya , Humayun Irshad , Andrew H. Beck

Introduction: Nottingham grading system is a major prognostic factor for invasive breast carcinoma (IBC). Its determination requires the evaluation of the mitotic score (MS) which is subject to low intra- and inter-observer reproducibility.…

Immunohistochemistry (IHC) plays a crucial role in pathology as it detects the over-expression of protein in tissue samples. However, there are still fewer machine learning model studies on IHC's impact on accurate cancer grading. We…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Jun Wang , Yu Mao , Yufei Cui , Nan Guan , Chun Jason Xue

Histopathological image analysis is the gold standard to diagnose cancer. Carcinoma is a subtype of cancer that constitutes more than 80% of all cancer cases. Squamous cell carcinoma and adenocarcinoma are two major subtypes of carcinoma,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Swathi Prabhua , Keerthana Prasada , Antonio Robels-Kelly , Xuequan Lu

Breast ultrasound diagnosis typically proceeds from global lesion localization to local sign assessment and then evidence integration to assign a BI-RADS category and determine benignity or malignancy. Many existing methods rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Yali Zhu , Kang Zhou , Dingbang Wu , Gaofeng Meng

While artificial intelligence (AI) algorithms continue to rival human performance on a variety of clinical tasks, the question of how best to incorporate these algorithms into clinical workflows remains relatively unexplored. We…

Dermatological conditions affect 1.9 billion people globally, yet accurate diagnosis remains challenging due to limited specialist availability and complex clinical presentations. Family history significantly influences skin disease…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Satya Narayana Panda , Vaishnavi Kukkala , Spandana Iyer