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Personalized medicine has become an important part of medicine, for instance predicting individual drug responses based on genomic information. However, many current statistical methods are not tailored to this task, because they overlook…

Applications · Statistics 2019-10-03 Shih-Ting Huang , Yannick Düren , Kristoffer H. Hellton , Johannes Lederer

Clinical dataset labels are rarely certain as annotators disagree and confidence is not uniform across cases. Typical aggregation procedures, such as majority voting, obscure this variability. In simple experiments on medical imaging…

We study the problem of learning to choose from m discrete treatment options (e.g., news item or medical drug) the one with best causal effect for a particular instance (e.g., user or patient) where the training data consists of passive…

Machine Learning · Statistics 2017-08-02 Nathan Kallus

Ordering the expected outcomes across a collection of clusters after performing a covariate adjustment commonly arises in many applied settings, such as healthcare provider evaluation. Regression parameters in such covariate adjustment…

Methodology · Statistics 2025-11-21 Nicholas C. Henderson , Nicholas Hartman

We consider the problem of ranking objects from noisy pairwise comparisons, for example, ranking tennis players from the outcomes of matches. We follow a standard approach to this problem and assume that each object has an unobserved…

Social and Information Networks · Computer Science 2025-12-18 Daniel Sánchez Catalina , George T. Cantwell

In Recommender System (RS), explanations help users understand why items are recommended and can enhance a system's transparency, persuasiveness, engagement, and trust, which are known as explanation goals. However, evaluating the…

Information Retrieval · Computer Science 2025-12-17 André Levi Zanon , Marcelo Garcia Manzato , Leonardo Rocha

In this paper, we present a novel approach to identify feature specific expressions of opinion in product reviews with different features and mixed emotions. The objective is realized by identifying a set of potential features in the review…

Information Retrieval · Computer Science 2012-09-19 Subhabrata Mukherjee , Pushpak Bhattacharyya

For automated assessment of knee MRI scans, both accuracy and interpretability are essential for clinical use and adoption. Traditional radiomics rely on predefined features chosen at the population level; while more interpretable, they are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Yaxi Chen , Simin Ni , Shuai Li , Shaheer U. Saeed , Aleksandra Ivanova , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress…

Machine Learning · Computer Science 2018-03-05 Dev Goyal , Zeeshan Syed , Jenna Wiens

Identifying clinically relevant biomarkers and developing predictive models are central challenges in biomedical research. Biomarkers are commonly used for disease screening, and some provide information not only on the presence or absence…

Methodology · Statistics 2025-08-21 Kazuharu Harada , Shuichi Kawano , Masataka Taguri

The aim of this paper is to firmly establish subjective fiducial inference as a rival to the more conventional schools of statistical inference, and to show that Fisher's intuition concerning the importance of the fiducial argument was…

Statistics Theory · Mathematics 2021-04-08 Russell J. Bowater

Clinical evidence encompasses the associations and impacts between patients, interventions (such as drugs or physiotherapy), problems, and outcomes. The goal of recommending clinical evidence is to provide medical practitioners with…

Computation and Language · Computer Science 2023-04-05 Maolin Luo , Xiang Zhang

Recommendation algorithms typically build models based on historical user-item interactions (e.g., clicks, likes, or ratings) to provide a personalized ranked list of items. These interactions are often distributed unevenly over different…

Information Retrieval · Computer Science 2021-03-16 Ziwei Zhu , Jianling Wang , James Caverlee

The paper introduces a new estimation method for the standard linear regression model. The procedure is not driven by the optimisation of any objective function rather, it is a simple weighted average of slopes from observation pairs. The…

Econometrics · Economics 2024-02-27 Felix Chan , Laszlo Matyas

Reliable determination of sensory thresholds is the holy grail of signal detection theory. However, there exists no gold standard for the estimation of thresholds based on neurophysiological parameters, although a reliable estimation method…

Quantitative Methods · Quantitative Biology 2019-10-01 Achim Schilling , Richard Gerum , Patrick Krauss , Claus Metzner , Konstantin Tziridis , Holger Schulze

While much of the causal inference literature has focused on addressing internal validity biases, both internal and external validity are necessary for unbiased estimates in a target population of interest. However, few generalizability…

Methodology · Statistics 2023-04-07 Irina Degtiar , Tim Layton , Jacob Wallace , Sherri Rose

We propose novel estimators for categorical and continuous treatments by using an optimal covariate balancing strategy for inverse probability weighting. The resulting estimators are shown to be consistent and asymptotically normal for…

Methodology · Statistics 2025-09-08 Seong-ho Lee , Yanyuan Ma , Xavier de Luna

Matching in causal inference from observational data aims to construct treatment and control groups with similar distributions of covariates, thereby reducing confounding and ensuring an unbiased estimation of treatment effects. This…

Artificial Intelligence · Computer Science 2025-04-15 Sahil Shikalgar , Md. Noor-E-Alam

In this paper we study approaches for dealing with treatment when developing a clinical prediction model. Analogous to the estimand framework recently proposed by the European Medicines Agency for clinical trials, we propose a…

The restricted polynomially-tilted pairwise interaction (RPPI) distribution gives a flexible model for compositional data. It is particularly well-suited to situations where some of the marginal distributions of the components of a…

Methodology · Statistics 2023-05-15 Janice L. Scealy , Kassel L. Hingee , John T. Kent , Andrew T. A. Wood