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Positron emission tomography (PET) is widely used for clinical diagnosis. As PET suffers from low resolution and high noise, numerous efforts try to incorporate anatomical priors into PET image reconstruction, especially with the…
Purpose: To investigate whether synthetically generated fractal data can be used to train deep learning (DL) models for dynamic MRI reconstruction, thereby avoiding the privacy, licensing, and availability limitations associated with…
Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated for during image reconstruction. The development of advanced…
Objective: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a larger angle of acceptance. However, this extended angle…
Magnetic resonance imaging (MRI) and positron emission tomography (PET) are increasingly used in multimodal analysis of neurodegenerative disorders. While MRI is broadly utilized in clinical settings, PET is less accessible. Many studies…
Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…
Low-dose CT imaging requires reconstruction from noisy indirect measurements which can be defined as an ill-posed linear inverse problem. In addition to conventional FBP method in CT imaging, recent compressed sensing based methods exploit…
Patient motion is well-known for degrading image quality during medical imaging. Especially positron emission tomography (PET) is susceptible to motion due to its usually long scan times. In hybrid PET/MRI (magnetic resonance imaging),…
Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…
Positron emission tomography (PET) is widely utilized for cancer detection due to its ability to visualize functional and biological processes in vivo. PET images are usually reconstructed from histogrammed raw data (sinograms) using…
Parametric images provide insight into the spatial distribution of physiological parameters, but they are often extremely noisy, due to low SNR of tomographic data. Direct estimation from projections allows accurate noise modeling,…
Synthetic PET images are valuable for quantitative imaging workflow development, scalable virtual imaging trials, and deep learning model training, but conventional physics-based simulation approaches are computationally intensive, limited…
Positron Emission Tomography (PET) imaging is a vital tool in medical diagnostics, offering detailed insights into molecular processes within the human body. However, PET images often suffer from complicated noise, which can obscure…
[$^{18}$F]fluorodeoxyglucose (FDG) positron emission tomography (PET) has emerged as a crucial tool in identifying the epileptic focus, especially in cases where magnetic resonance imaging (MRI) diagnosis yields indeterminate results. FDG…
Due to various physical degradation factors and limited counts received, PET image quality needs further improvements. The denoising diffusion probabilistic models (DDPM) are distribution learning-based models, which try to transform a…
Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…
We introduce Neural Deformation Graphs for globally-consistent deformation tracking and 3D reconstruction of non-rigid objects. Specifically, we implicitly model a deformation graph via a deep neural network. This neural deformation graph…
Dynamic positron emission tomography imaging (dPET) provides temporally resolved images of a tracer enabling a quantitative measure of physiological processes. Voxel-wise physiologically-based pharmacokinetic (PBPK) modeling of the time…
Objective Positron emission tomography (PET) allows imaging of patho-physiological information as a form of rate constants from a dynamic image. The rate constant image(s) may be affected from noise on the dynamic image. We introduced an…
Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…