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This article studies experimental design in settings where the experimental units are large aggregate entities (e.g., markets), and only one or a small number of units can be exposed to the treatment. In such settings, randomization of the…

Methodology · Statistics 2025-04-24 Alberto Abadie , Jinglong Zhao

Leveraging external controls -- relevant individual patient data under control from external trials or real-world data -- has the potential to reduce the cost of randomized controlled trials (RCTs) while increasing the proportion of trial…

Methodology · Statistics 2022-07-13 Yanyao Yi , Ying Zhang , Yu Du , Ting Ye

Identifying and controlling bias is a key problem in empirical sciences. Causal diagram theory provides graphical criteria for deciding whether and how causal effects can be identified from observed (nonexperimental) data by covariate…

Artificial Intelligence · Computer Science 2012-02-20 Johannes Textor , Maciej Liskiewicz

Recent studies show that Natural Language Processing (NLP) technologies propagate societal biases about demographic groups associated with attributes such as gender, race, and nationality. To create interventions and mitigate these biases…

Computation and Language · Computer Science 2022-10-17 Sunipa Dev , Emily Sheng , Jieyu Zhao , Aubrie Amstutz , Jiao Sun , Yu Hou , Mattie Sanseverino , Jiin Kim , Akihiro Nishi , Nanyun Peng , Kai-Wei Chang

This article extends the widely-used synthetic controls estimator for evaluating causal effects of policy changes to quantile functions. The proposed method provides a geometrically faithful estimate of the entire counterfactual quantile…

Econometrics · Economics 2022-01-03 Florian Gunsilius

Observational healthcare data offer the potential to estimate causal effects of medical products on a large scale. However, the confidence intervals and p-values produced by observational studies only account for random error and fail to…

Applications · Statistics 2024-05-02 Jami J. Mulgrave , David Madigan , George Hripcsak

It is not always clear how to adjust for control data in causal inference, balancing the goals of reducing bias and variance. We show how, in a setting with repeated experiments, Bayesian hierarchical modeling yields an adaptive procedure…

Methodology · Statistics 2025-01-23 Andrew Gelman , Matthijs Vákár

Comparison and contrast are the basic means to unveil causation and learn which treatments work. To build good comparison groups, randomized experimentation is key, yet often infeasible. In such non-experimental settings, we illustrate and…

Methodology · Statistics 2024-01-30 Ambarish Chattopadhyay , Jose R. Zubizarreta

A common concern with Bayesian methodology in scientific contexts is that inferences can be heavily influenced by subjective biases. As presented here, there are two types of bias for some quantity of interest: bias against and bias in…

Statistics Theory · Mathematics 2019-03-06 Michael Evans , Yang Guo

In multiple testing several criteria to control for type I errors exist. The false discovery rate, which evaluates the expected proportion of false discoveries among the rejected null hypotheses, has become the standard approach in this…

Methodology · Statistics 2023-11-03 Jacobo de Uña-Álvarez

Invariant causal prediction provides a useful framework for identifying causal predictors of a response using heterogeneous data from multiple environments. One valuable property of the original invariant causal prediction method is that it…

Methodology · Statistics 2026-05-21 Jinzhou Li , Jelle J Goeman

This survey analyses the role of data-driven methodologies for pandemic modelling and control. We provide a roadmap from the access to epidemiological data sources to the control of epidemic phenomena. We review the available methodologies…

Systems and Control · Electrical Eng. & Systems 2021-08-23 Teodoro Alamo , Daniel G. Reina , Pablo Millán Gata , Victor M. Preciado , Giulia Giordano

One of the most important branches of nonlinear control theory is the so-called sliding-mode. Its aim is the design of a (nonlinear) feedback law that brings and maintains the state trajectory of a dynamic system on a given sliding surface.…

Systems and Control · Electrical Eng. & Systems 2021-09-14 Mauro Bisiacco , Gianluigi Pillonetto

In prior work we have introduced an asymptotic threshold of sufficient randomness for causal inference from observational data. In this paper we extend that prior work in three main ways. First, we show how to empirically estimate a lower…

Methodology · Statistics 2023-09-07 Brian Knaeble , Braxton Osting , Placede Tshiaba

Estimating the causal effect of a treatment or health policy with observational data can be challenging due to an imbalance of and a lack of overlap between treated and control covariate distributions. In the presence of limited overlap,…

Methodology · Statistics 2025-03-24 Martha Barnard , Jared D. Huling , Julian Wolfson

Testing for causation, defined as the preceding impact of the past values of one variable on the current value of another one when all other pertinent information is accounted for, is increasingly utilized in empirical research of the…

Econometrics · Economics 2021-06-22 Abdulnasser Hatemi-J

In this paper, we adopt results in nonlinear time series analysis for causal inference in dynamical settings.~Our motivation is policy analysis with panel data, particularly through the use of "synthetic control" methods. These methods…

Methodology · Statistics 2020-03-03 Yi Ding , Panos Toulis

We consider the issue of biases in scholarly research, specifically, in peer review. There is a long standing debate on whether exposing author identities to reviewers induces biases against certain groups, and our focus is on designing…

Methodology · Statistics 2020-01-01 Ivan Stelmakh , Nihar B. Shah , Aarti Singh

We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample selection and both type I (false positive) and type II…

Applications · Statistics 2021-12-28 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

We develop a feedback control method for networked epidemic spreading processes. In contrast to most prior works which consider mean field, open-loop control schemes, the present work develops a novel framework for feedback control of…

Optimization and Control · Mathematics 2017-03-23 Nicholas J. Watkins , Cameron Nowzari , George J. Pappas