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Breast cancer is a heterogeneous disease with different molecular subtypes, clinical behavior, treatment responses as well as survival outcomes. The development of a reliable, accurate, available and inexpensive method to predict the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Mohaddeseh Chegini , Ali Mahloojifar

Medical image labels are often organized by taxonomies (e.g., organ - tissue - subtype), yet standard self-supervised learning (SSL) ignores this structure. We present a hierarchy-preserving contrastive framework that makes the label tree a…

Quantitative Methods · Quantitative Biology 2025-11-07 Alif Elham Khan

Accurate survival prediction is crucial for development of precision cancer medicine, creating the need for new sources of prognostic information. Recently, there has been significant interest in exploiting routinely collected clinical and…

Machine Learning · Computer Science 2021-03-23 Sejin Kim , Michal Kazmierski , Benjamin Haibe-Kains

The goal in extreme multi-label classification (XMC) is to tag an instance with a small subset of relevant labels from an extremely large set of possible labels. In addition to the computational burden arising from large number of training…

Machine Learning · Statistics 2020-07-02 Erik Schultheis , Mohammadreza Qaraei , Priyanshu Gupta , Rohit Babbar

Automation-assisted cervical screening via Pap smear or liquid-based cytology (LBC) is a highly effective cell imaging based cancer detection tool, where cells are partitioned into "abnormal" and "normal" categories. However, the success of…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Ling Zhang , Le Lu , Isabella Nogues , Ronald M. Summers , Shaoxiong Liu , Jianhua Yao

Hierarchical classification is a crucial task in many applications, where objects are organized into multiple levels of categories. However, conventional classification approaches often neglect inherent inter-class relationships at…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Julius Ott , Nastassia Vysotskaya , Huawei Sun , Lorenzo Servadei , Robert Wille

When evaluating the performance of clinical machine learning models, one must consider the deployment population. When the population of patients with observed labels is only a subset of the deployment population (label selection), standard…

Machine Learning · Computer Science 2022-09-20 Conor K. Corbin , Michael Baiocchi , Jonathan H. Chen

In this work we present a clustering technique called \textit{multi-level conformal clustering (MLCC)}. The technique is hierarchical in nature because it can be performed at multiple significance levels which yields greater insight into…

Machine Learning · Statistics 2020-06-25 Ilia Nouretdinov , James Gammerman , Matteo Fontana , Daljit Rehal

Deep learning for radiologic image analysis is a rapidly growing field in biomedical research and is likely to become a standard practice in modern medicine. On the publicly available NIH ChestX-ray14 dataset, containing X-ray images that…

Image and Video Processing · Electrical Eng. & Systems 2026-02-25 Daniel J. Strick , Carlos Garcia , Anthony Huang , Thomas Gardos

Technological and computational advances continuously drive forward the broad field of deep learning. In recent years, the derivation of quantities describing theuncertainty in the prediction - which naturally accompanies the modeling…

Machine Learning · Computer Science 2022-05-31 Christoph Koller , Göran Kauermann , Xiao Xiang Zhu

Spectral clustering is a celebrated algorithm that partitions objects based on pairwise similarity information. While this approach has been successfully applied to a variety of domains, it comes with limitations. The reason is that there…

Statistics Theory · Mathematics 2018-05-24 Kwangjun Ahn , Kangwook Lee , Changho Suh

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Evaluating AI-generated medical image segmentations for clinical acceptability poses a significant challenge, as traditional pixelagreement metrics often fail to capture true diagnostic utility. This paper introduces Hierarchical Clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jiaxi Sheng , Leyi Yu , Haoyue Li , Yifan Gao , Xin Gao

CNNs, RNNs, GCNs, and CapsNets have shown significant insights in representation learning and are widely used in various text mining tasks such as large-scale multi-label text classification. However, most existing deep models for…

Information Retrieval · Computer Science 2019-06-13 Hao Peng , Jianxin Li , Qiran Gong , Senzhang Wang , Lifang He , Bo Li , Lihong Wang , Philip S. Yu

Multi-label classification is a common challenge in various machine learning applications, where a single data instance can be associated with multiple classes simultaneously. The current paper proposes a novel tree-based method for…

Methodology · Statistics 2024-05-01 Chhavi Tyagi , Wenge Guo

One important characteristic of modern fault classification systems is the ability to flag the system when faced with previously unseen fault types. This work considers the unknown fault detection capabilities of deep neural network-based…

Machine Learning · Computer Science 2024-03-27 Nurettin Sergin , Jiayu Huang , Tzyy-Shuh Chang , Hao Yan

The imperative for early detection of type 2 diabetes mellitus (T2DM) is challenged by its asymptomatic onset and dependence on suboptimal clinical diagnostic tests, contributing to its widespread global prevalence. While research into…

Machine Learning · Computer Science 2024-12-17 Sanjana Gundapaneni , Zhuo Zhi , Miguel Rodrigues

Multi-label classification of chest X-ray images is frequently performed using discriminative approaches, i.e. learning to map an image directly to its binary labels. Such approaches make it challenging to incorporate auxiliary information…

Artificial Intelligence · Computer Science 2021-03-11 Anjany Sekuboyina , Daniel Oñoro-Rubio , Jens Kleesiek , Brandon Malone

Hyperdimensional computing (HDC) is a method to perform classification that uses binary vectors with high dimensions and the majority rule. This approach has the potential to be energy-efficient and hence deemed suitable for…

Machine Learning · Computer Science 2023-10-13 Zhanglu Yan , Shida Wang , Kaiwen Tang , Weng-Fai Wong

Optimal performance is critical for decision-making tasks from medicine to autonomous driving, however common performance measures may be too general or too specific. For binary classifiers, diagnostic tests or prognosis at a timepoint,…