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Synthetic biology is a recent area of biological engineering, whose aim is to provide cells with novel functionalities. A number of important results regarding the development of control circuits in synthetic biology have been achieved…

Systems and Control · Electrical Eng. & Systems 2024-11-11 Antón Pardo , Sandra Díaz Seoane , Dorin A. Ionescu , Antonis Papachristodoulou , Alejandro F. Villaverde

Biopolymer looping is a dynamic process that occurs ubiquitously in cells for gene regulation, protein folding, etc. In cellular environments, biopolymers are often subject to tensions which are either static, or temporally fluctuating far…

Soft Condensed Matter · Physics 2012-02-07 Jaeoh Shin , Wokyung Sung

By analytically solving some simple models of phase-ordering kinetics, we suggest a mechanism for the onset of non-equilibrium behaviour in colloid-polymer mixtures. These mixtures can function as models of atomic systems; their physics…

Soft Condensed Matter · Physics 2016-08-31 R. M. L. Evans , W. C. K. Poon

Organic electrochemical transistors formed by in operando electropolymerization of the semiconducting channel are increasingly becoming recognized as a simple and effective implementation of synapses in neuromorphic hardware. However, very…

Engineered living materials (ELMs) are the most relevant contemporary revolution in materials science and engineering. These ELMs aim to outperform current examples of "smart", active or multifunctional materials, enabling countless…

Biological Physics · Physics 2021-10-19 Andrés Díaz Lantada , Jan G. Korvink , Monsur Islam

A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical…

Biological Physics · Physics 2021-05-11 Na Liu

Developing successful scaffolds requires clinicians to adopt a multidisciplinary approach in order to understand and stimulate the natural bone regeneration process. A variety of natural and synthetic biomaterials, including naturally…

Tissues and Organs · Quantitative Biology 2016-10-28 Elaine R. Durham , Giuseppe Tronci , Xuebin Yang , David J. Wood , Stephen J. Russell

Active processes in living systems generate nonequilibrium forces that deform embedded passive macromolecules. To understand how such dynamics influence polymer conformation, we study a flexible passive chain in an active nematic fluid.…

Soft Condensed Matter · Physics 2025-09-30 Zahra K. Valei , Davide Marenduzzo , Tyler N. Shendruk

We employ a multiscale approach to model the translocation of biopolymers through nanometer size pores. Our computational scheme combines microscopic Langevin molecular dynamics (MD) with a mesoscopic lattice Boltzmann (LB) method for the…

Biological Physics · Physics 2011-11-10 Maria Fyta , Simone Melchionna , Efthimios Kaxiras , Sauro Succi

We provide a non-equilibrium thermodynamic description of the life-cycle of a droplet based, chemically feasible, system of protocells. By coupling the protocells metabolic kinetics with its thermodynamics, we demonstrate how the system can…

Polymers consisting of more than one type of monomer, known as copolymers, are vital to both living and synthetic systems. Copolymerisation has been studied theoretically in a number of contexts, often by considering a Markov process in…

Polymers with active segments constitute prospective future materials and are used as a model for some biological systems such as chromatin. The directions of the active forces are typically introduced with temporal or spatial correlations…

Soft Condensed Matter · Physics 2024-11-25 Adam H. T. P. Höfler , Iurii Chubak , Christos N. Likos , Jan Smrek

The equilibrium statistical mechanics of classical directed polymers in 2 dimensions is well known to be equivalent to the imaginary-time quantum dynamics of a 1+1-dimensional many-particle system, with polymer configurations corresponding…

Soft Condensed Matter · Physics 2013-05-30 D. Zeb Rocklin , Shina Tan , Paul M. Goldbart

Multicomponent phase separation is a routine occurrence in both living and synthetic systems. Thermodynamics provides a straightforward path to determine the phase boundaries that characterize these transitions for systems at equilibrium.…

Statistical Mechanics · Physics 2025-12-08 Yu-Jen Chiu , Daniel Evans , Ahmad K. Omar

The mechanics of complex soft matter often cannot be understood in the classical physical frame of flexible polymers or rigid rods. The underlying constituents are semiflexible polymers, whose finite bending stiffness ($\kappa$) leads to…

The physiological tradition of biological research analyzes biological systems using reduced descriptions much as an engineer uses a 'black box' description of an amplifier. Simple models have been used by physiologists for a very long…

Other Quantitative Biology · Quantitative Biology 2012-07-06 Bob Eisenberg

The presence of nanoparticles in a diblock copolymer leads to changes in the morphology and properties of the matrix and can produce highly organized hybrid materials. The resulting material properties depend not only on the polymer…

Soft Condensed Matter · Physics 2018-05-30 Javier Diaz , Marco Pinna , Andrei Zvelindovsky , Adelchi Asta , Ignacio Pagonabarraga

Entangled polymers are an important class of materials for their toughness, processability, and functionalizability. However, physically detailed modeling of highly entangled polymers can prove challenging, especially as one considers…

Soft Condensed Matter · Physics 2024-10-28 Vickie Chen , Brandon Wang , Joseph D. Peterson

Soft colloids allow to explore high density states well beyond random close packing. An important open question is whether softness controls the dynamics under these dense conditions. While experimental works reported conflicting results,…

Soft Condensed Matter · Physics 2021-06-08 Nicoletta Gnan , Emanuela Zaccarelli

This position paper argues that next-generation non-equilibrium-inspired generative models will provide the essential foundation for better modeling real-world complex dynamical systems. While many classical generative algorithms draw…

Computational Engineering, Finance, and Science · Computer Science 2025-05-27 Jiazhen Liu , Ruikun Li , Huandong Wang , Zihan Yu , Chang Liu , Jingtao Ding , Yong Li
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